Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Alena Yermalovich"'
Autor:
Alena Yermalovich, Zarin Mohsenin, Bruno Giotti, Douglas Wheeler, Kelly Xu, Alexander Tsankov, Matthew Meyerson
Publikováno v:
Cancer Research. 83:4583-4583
Cancer genome sequencing studies have identified multiple novel tumor suppressor genes, including the FTSJD1 or CMTR2 gene that is subject to statistically significant levels of both nonsense and frameshift mutations in lung adenocarcinoma. However,
Autor:
Patricia Sousa, Trista E. North, Ronald Mathieu, Pavlos Missios, R. Grant Rowe, Michael A. Morse, George Q. Daley, Edroaldo Lummertz da Rocha, Alena Yermalovich, Deepak Kumar Jha, Mark D. Fleming, William Marion, Jessica Barragan
Publikováno v:
Journal of Experimental Medicine. 216:527-538
Leukemia phenotypes vary with age of onset. Delineating mechanisms of age specificity in leukemia could improve disease models and uncover new therapeutic approaches. Here, we used heterochronic transplantation of leukemia driven by MLL/KMT2A translo
Autor:
Areum Han, areum Han, Alena Yermalovich, Vanessa Lundin, Daniel Pearson, Brianna Hilton, Arianna Markel, Patricia Sousa, Michael Morse, Yosra Zhang, Bahareh Derafshi, Stephanie Chou, John Atwater, Yang Tang, Jenna Frame, Mariam Hachimi, Caroline Kubaczka, Phoebe Hunter, Yu Huang, Vivian Morris, Ran Jing, Jihan Osborne, Trista North, Thorsten Schlaeger, George Daley
Publikováno v:
Experimental Hematology. 111:S93
Autor:
Daisy A. Robinton, Daniel S. Pearson, Jihan K. Osborne, Michael J. Chen, Sean B. Wilson, Melissa A. Kinney, Helen Montie, Alexander N. Combes, Areum Han, Melissa H. Little, Alena Yermalovich, Patricia Sousa, George Q. Daley
Publikováno v:
Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
In humans and in mice the formation of nephrons during embryonic development reaches completion near the end of gestation, after which no new nephrons are formed. The final nephron complement can vary 10-fold, with reduced nephron number predisposing
Autor:
Alena Yermalovich, Jenna M. Frame, Mariam Hachimi, Michael A. Morse, George Q. Daley, Brianna Hilton, Thorsten M. Schlaeger, Patricia Sousa, Yosra Zhang, Daniel S. Pearson, Vanessa Lundin, Jihan K. Osborne, Areum Han, Trista E. North, Yu Chung Huang, Vivian Morris, Ran Jing, Pheobe Hunter, John Atwater, Caroline Kubaczka
Publikováno v:
Blood. 136:3-3
Erythropoiesis is an intricate process by which lineage-committed erythroid progenitors become mature red blood cells. Reticulocytes are terminal-staged, immature red blood cells with residual RNA after enucleation. In the absence of pathology, retic
Autor:
Michael J. Chen, Alexander N. Combes, Daisy A. Robinton, Melissa A. Kinney, Areum Han, Patricia Sousa, Melissa H. Little, Alena Yermalovich, George Q. Daley, Daniel S. Pearson, Sean B. Wilson, Jihan K. Osborne, Helen Montie
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-1 (2020)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Autor:
R Grant, Rowe, Edroaldo, Lummertz da Rocha, Patricia, Sousa, Pavlos, Missios, Michael, Morse, William, Marion, Alena, Yermalovich, Jessica, Barragan, Ronald, Mathieu, Deepak Kumar, Jha, Mark D, Fleming, Trista E, North, George Q, Daley
Publikováno v:
The Journal of Experimental Medicine
Rowe and colleagues show that hematopoietic cells with MLL translocations undergoing leukemogenesis in neonatal mice yield mixed-lineage early B-lymphoid/myeloid leukemia while identical cells in adults generate myeloid leukemia, demonstrating that t
Autor:
Jihan K. Osborne, Patricia Sousa, Areum Han, Kemi E. Akinnola, Sutheera Ratanasirintrawoot, Jessica Barragan, Trista E. North, Melissa A. Kinney, Linda T. Vo, Alena Yermalovich, Kaloyan M. Tsanov, Daniel S. Pearson, Ross J. Metzger, George Q. Daley
Publikováno v:
Cell reports
SUMMARY The molecular mechanisms that govern the choreographed timing of organ development remain poorly understood. Our investigation of the role of the Lin28a and Lin28b paralogs during the developmental process of branching morphogenesis establish
Autor:
Sun A. Kim, Gavin Meredith, Shann Ching Chen, Yuan Chieh Ku, Reiko Nishihara, Juhong Yang, Ho-Chou Tu, Zhi Rong Qian, Srinivas R. Viswanathan, Kentaro Inamura, George Q. Daley, Charles S. Fuchs, Yasutaka Sukawa, Kosuke Mima, Alena Yermalovich, Teppei Morikawa, Hao Zhu, Grace S. LaPier, Sarah Schwitalla, Shuji Ogino
Publikováno v:
Genes & Development. 29:1074-1086
Colorectal cancer (CRC) remains a major contributor to cancer-related mortality. LIN28A and LIN28B are highly related RNA-binding protein paralogs that regulate biogenesis of let-7 microRNAs and influence development, metabolism, tissue regeneration,
Autor:
Alena Yermalovich, Achia Urbach, Patricia Sousa, Masayuki Oginuma, Thorsten M. Schlaeger, Daisy A. Robinton, Areum Han, Antony Rodriguez, George Q. Daley, Edroaldo Lummertz da Rocha, Olivier Pourquié, Jérome Chal
Publikováno v:
Developmental Cell. 48:396-405.e3
The heterochronic genes Lin28a/b and let-7 regulate invertebrate development, but their functions in patterning the mammalian body plan remain unexplored. Here, we describe how Lin28/let-7 influence caudal vertebrae number during body axis formation.