Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Alena Y. Streletskaia"'
Autor:
Alena Y. Streletskaia, Viacheslav V. Senichkin, Tatiana A. Prikazchikova, Timofei S. Zatsepin, Boris Zhivotovsky, Gelina S. Kopeina
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
As an important regulator of apoptosis, Mcl-1 protein, a member of the Bcl-2 family, represents an attractive target for cancer treatment. The recent development of novel small molecule compounds has allowed Mcl-1-inhibitory therapy to proceed to cli
Externí odkaz:
https://doaj.org/article/fe281dc5d1934d109ba17179daeb6267
Autor:
Kopeina, Viacheslav V. Senichkin, Nikolay V. Pervushin, Alexey V. Zamaraev, Elena V. Sazonova, Anton P. Zuev, Alena Y. Streletskaia, Tatiana A. Prikazchikova, Timofei S. Zatsepin, Olga V. Kovaleva, Elena M. Tchevkina, Boris Zhivotovsky, Gelina S.
Publikováno v:
Cancers; Volume 14; Issue 1; Pages: 181
BH3 mimetics represent a promising tool in cancer treatment. Recently, the drugs targeting the Mcl-1 protein progressed into clinical trials, and numerous studies are focused on the investigation of their activity in various preclinical models. We in
Publikováno v:
Trends in Cell Biology. 29:549-562
Among cell death regulators, members of the Bcl-2 family are of interest because they are highly conserved across species and represent promising targets for anticancer therapy. This family and its associated proteins include more than 25 members, wi