Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Alena Shkumatava"'
Autor:
Barbara D. Fontana, Florian Reichmann, Ceinwen A. Tilley, Perrine Lavlou, Alena Shkumatava, Nancy Alnassar, Courtney Hillman, Karl Ægir Karlsson, William H. J. Norton, Matthew O. Parker
Publikováno v:
Translational Psychiatry, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Externalizing disorders (ED) are a cause of concern for public health, and their high heritability makes genetic risk factors a priority for research. Adhesion G-Protein-Coupled Receptor L3 (ADGRL3) is strongly linked to several EDs, and los
Externí odkaz:
https://doaj.org/article/af1d63eb851c490abd2dbe3aa798e77d
Autor:
Antoine Graindorge, Inês Pinheiro, Anna Nawrocka, Allison C. Mallory, Peter Tsvetkov, Noa Gil, Carlo Carolis, Frank Buchholz, Igor Ulitsky, Edith Heard, Mikko Taipale, Alena Shkumatava
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
RNA-interacting proteome can be identified by RNA affinity purification followed by mass spectrometry. Here the authors developed a different RNA-centric technology that combines high-throughput immunoprecipitation of RNA binding proteins and lucifer
Externí odkaz:
https://doaj.org/article/5e396512bb33457992f7bc69d0a77e2f
Publikováno v:
iScience, Vol 23, Iss 5, Pp - (2020)
Summary: CCCTC-binding factor (CTCF) is a conserved architectural protein that plays crucial roles in gene regulation and three-dimensional (3D) chromatin organization. To better understand mechanisms and evolution of vertebrate genome organization,
Externí odkaz:
https://doaj.org/article/3a422ca55eaf49ce9465bcc48df5536b
Autor:
Antoine Graindorge, Inês Pinheiro, Anna Nawrocka, Allison C. Mallory, Peter Tsvetkov, Noa Gil, Carlo Carolis, Frank Buchholz, Igor Ulitsky, Edith Heard, Mikko Taipale, Alena Shkumatava
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-1 (2020)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/50612a1967304f8d80162a06f09051f8
Publikováno v:
IUBMB Life. 75:458-470
LncRNAs represent an abundant group of noncoding transcripts, some of which carry out important regulatory functions. To survey the biological and molecular roles of lncRNAs, reliable strategies for their genetic inactivation are required. Several ln
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef2a1f75e6b01ad718678dbb42945317
https://doi.org/10.1002/iub.2690
https://doi.org/10.1002/iub.2690
Autor:
Hildur Sóley Sveinsdóttir, Christian Christensen, Haraldur Þorsteinsson, Perrine Lavalou, Matthew O. Parker, Alena Shkumatava, William H. J. Norton, Emile Andriambeloson, Stéphanie Wagner, Karl Ægir Karlsson
Publikováno v:
Neuropsychopharmacology.
ADHD is a highly prevalent neurodevelopmental disorder. The first-line therapeutic for ADHD, methylphenidate, can cause serious side effects including weight loss, insomnia, and hypertension. Therefore, the development of non-stimulant-based therapeu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fc0746b936bacb27f96a7a22df1a3b0
https://doi.org/10.1038/s41386-022-01505-z
https://doi.org/10.1038/s41386-022-01505-z
Autor:
Vikash Kumar, Xavier Sabaté-Cadenas, Isha Soni, Esther Stern, Vias Carine, Doron Ginsberg, Martin Dodel, Faraz K. Mardakheh, Alena Shkumatava, Eitan Shaulian
SummaryIdentification of key factors for cellular survival is a basis for therapy. We identified JUNI (linc01135) as a stress-regulated lncRNA, essential for cell survival and implicated in cancer. Besides regulating c-Jun expression we demonstrate c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0495ccc6de60f8d75458fa2498b15ba8
https://doi.org/10.1101/2022.06.21.496924
https://doi.org/10.1101/2022.06.21.496924
Autor:
Florian Constanty, Alena Shkumatava
Publikováno v:
Development. 148
The number of long noncoding RNAs (lncRNAs) with characterized developmental and cellular functions continues to increase, but our understanding of the molecular mechanisms underlying lncRNA functions, and how they are dictated by RNA sequences, rema
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25e75f687ffd17505686ef7d5f10c766
https://doi.org/10.1242/dev.182741
https://doi.org/10.1242/dev.182741
Publikováno v:
Trends in Biochemical Sciences
Trends in Biochemical Sciences, Elsevier, 2020, 45, pp.272-273. ⟨10.1016/j.tibs.2019.12.003⟩
Trends in Biochemical Sciences, 2020, 45 (3), pp.272-273. ⟨10.1016/j.tibs.2019.12.003⟩
Trends in Biochemical Sciences, Elsevier, 2020, 45, pp.272-273. ⟨10.1016/j.tibs.2019.12.003⟩
Trends in Biochemical Sciences, 2020, 45 (3), pp.272-273. ⟨10.1016/j.tibs.2019.12.003⟩
International audience
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16d13e607b359527dc3c7ad3b6e16ae8
https://hal.archives-ouvertes.fr/hal-03489898
https://hal.archives-ouvertes.fr/hal-03489898
Autor:
Robin C. Allshire, Madeleine Heep, Alena Shkumatava, Dónal O'Carroll, Yuka Kabayama, Lina Vasiliauskaitė, Yuvia A. Pérez-Rico, Ansgar Zoch, Rebecca V. Berrens, Juri Rappsilber, Atlanta G. Cook, Tania Auchynnikava, Theresa Schöpp
Publikováno v:
Nature
In mammals, the acquisition of the germline from the soma provides the germline with an essential challenge: the need to erase and reset genomic methylation1. In the male germline, RNA-directed DNA methylation silences young, active transposable elem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ce0128b501c405c72070577c37d9f09