Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Alena Semerádtová"'
Autor:
Olga Janouskova, Regina Herma, Alena Semeradtova, David Poustka, Michaela Liegertova, Hana Auer Malinska, Jan Maly
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Despite extensive study of extracellular vesicles (EVs), specifically exosomes (EXs) as biomarkers, important modulators of physiological or pathological processes, or therapeutic agents, relatively little is known about nonconventional sources of EX
Externí odkaz:
https://doaj.org/article/9cc16f27d2004212952e91850bd77298
Autor:
Michaela Liegertová, Alena Semerádtová, Michaela Kocholatá, Michaela Průšová, Lenka Němcová, Marcel Štofik, Sylvie Kříženecká, Jan Malý, Olga Janoušková
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract The slug Arion vulgaris has attracted major attention as one of the worst invasive herbivore pests in Europe and is renowned for the stiff mucus it secretes for locomotion. In this study we focused on the isolation and characterisation of ex
Externí odkaz:
https://doaj.org/article/f85a2389946043a0b868d4db4d2bef5d
Publikováno v:
Biosensors and Bioelectronics. 227:115155
Publikováno v:
Sensors and Actuators B: Chemical. 272:441-447
Recent developments in molecular evolution technologies have led to novel types of high-affinity recombinant protein binders (PB) able to substitute antibodies in many diagnostic and therapeutic applications. Despite almost a decade of research, they
Autor:
Kateřina Kolářová, Václav Šícha, Jindřich Matoušek, Alena Semerádtová, Monika Benkocká, Zdeňka Kolská
Publikováno v:
Applied Surface Science. 441:120-129
The surface of polystyrene foil (PS) was chemically modified. Firstly, the surface was pre-treated with Piranha solution. The activated surface was grafted by selected amino-compounds (cysteamine, ethylenediamine or chitosan) and/or subsequently graf
Autor:
Milan Kuchař, Jiří Smejkal, Natalya Panova, Jan Malý, Marcel Štofik, Petr Aubrecht, Alena Semerádtová, Petr Malý
Publikováno v:
Biosensors and Bioelectronics. 172:112784
Cell immunocapture microfluidic devices represent a rapidly developing field with many potential applications in medical diagnostics. The core of such approach lies in the cell binding to antibody coated surfaces through their surface receptors. Here
Autor:
Peter Sebo, Marek Maly, Dietmar Appelhans, Ondrej Stanek, Jan Frolik, Marcel Štofik, Dominika Wrobel, Jan Čermák, Lucie Červenková Št’astná, Jan Maly, Milan Kuchar, Petr Maly, Franka Ennen, Tereza Knapova, Alena Semerádtová
Publikováno v:
Macromolecular Bioscience. 16:553-566
For the design of a biohybrid structure as a ligand-tailored drug delivery system (DDS), it is highly sophisticated to fabricate a DDS based on smoothly controllable conjugation steps. This article reports on the synthesis and the characterization of
Autor:
Dominika Wrobel, Michaela Liegertová, Regina Herma, Marcel Štofik, Monika Müllerová, Marek Maly, Jan Maly, Dietmar Appelhans, Tomáš Strašák, Alena Semerádtová
Publikováno v:
International journal of pharmaceutics. 562
Non-viral gene delivery vectors studied in the gene therapy applications are often designed with the cationic nitrogen containing groups necessary for binding and cell release of nucleic acids. Disadvantage is a relatively high toxicity which restric
Autor:
Zdeňka Kolská, Petr Slepička, Ondřej Staněk, Jan Malý, Marcel Štofik, O. Neděla, Alena Semerádtová
Publikováno v:
Colloids and surfaces. B, Biointerfaces. 165
Herein, we report a novel concept of low-cost flexible platform for fluorescence-based biosensor. The surface of polyethylene naphthalate (PEN) foil was exposed to KrF excimer laser through a photolitographic contact mask. Laser initiated surface mod
Autor:
Dietmar Appelhans, Elzbieta Pedziwiatr-Werbicka, Jan Maly, Barbara Klajnert, Maria Bryszewska, Marek Maly, Alena Semerádtová, Marian Zaborski, Andrea Danani
Publikováno v:
Scopus-Elsevier
Dendrimers are artificial polymeric macromolecules which are widely considered to be a promising tool for future gene therapy applications. They have been used as efficient delivery vehicles for antisense oligonucleotides targeting the interior of ce