Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Alena Rudolph"'
Autor:
Martín Fañanás-Mastral, Yange Huang, Manuel Perez, Alena Rudolph, Anne M. Meuwese, Ben L. Feringa, Tim den Hartog, Adriaan J. Minnaard
Publikováno v:
ACS Catalysis, 5(2), 560-574. AMER CHEMICAL SOC
The enantioselective 1,6-addition to unsaturated carbonyl compounds otters unique opportunities to study the range of selectivities one can obtain using Cu catalysis. Here, a substrate-reagent approach to obtain structural information on the mechanis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b81614179be79653a595f975fe80fe2b
https://research.rug.nl/en/publications/dca1ecb2-a8fe-408b-9110-09f4308b7ba2
https://research.rug.nl/en/publications/dca1ecb2-a8fe-408b-9110-09f4308b7ba2
Autor:
Bernard Feringa, Pieter H. Bos, Martin Fananas Mastral, Syuzanna R. Harutyunyan, Alena Rudolph, Manuel Perez
Publikováno v:
Angewandte Chemie-International Edition, 51(8), 1922-1925. WILEY-V C H VERLAG GMBH
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c492995eec08fcc09b1d1a80f19c574
https://doi.org/10.1002/anie.201107840
https://doi.org/10.1002/anie.201107840
Publikováno v:
Angewandte Chemie-International Edition, 50(26), 5834-5838. WILEY-V C H VERLAG GMBH
The convenient one-pot procedure includes conjugate addition of alkylmagnesium bromides to α,β-unsaturated esters and subsequent oxidative cyclization.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::418131b4c7a6b72b5a19f82b83f1282f
https://doi.org/10.1002/ange.201102069
https://doi.org/10.1002/ange.201102069
Autor:
Alena Rudolph, Pieter H. Bos, Ben L. Feringa, Manuel Perez, Syuzanna R. Harutyunyan, Martín Fañanás-Mastral
Publikováno v:
Nature Chemistry, 3(5), 377-381. Nature Publishing Group
Carbon-carbon bond formation is the basis for the biogenesis of nature's essential molecules. Consequently, it lies at the heart of the chemical sciences. Chiral catalysts have been developed for asymmetric C-C bond formation to yield single enantiom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f7f5418b23f800b3b953dcdc712c3a2
https://doi.org/10.1038/nchem.1009
https://doi.org/10.1038/nchem.1009
Publikováno v:
Tetrahedron Letters. 54:7059-7061
A new synthetic strategy towards the C27–C35 subunit of Eribulin (1) has been devised to include a protected 1,2-amino alcohol at C34–C35. Early introduction of the C35 amino group in the synthesis of 1 increases the efficiency of the route. This
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::488b29d7ad8b27cbc96cf8b1180a71b2
https://doi.org/10.1016/j.tetlet.2013.10.077
https://doi.org/10.1016/j.tetlet.2013.10.077
Autor:
Alena Rudolph, Mark Lautens
Publikováno v:
Angewandte Chemie International Edition. 48:2656-2670
Secondary, but second to none: The use of secondary alkyl halides in transition-metal-catalyzed cross-coupling reactions (see scheme) has advanced significantly over the last five years. Selected examples of these transformations are examined, includ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be2af9784984cf9f031321962d1636e8
https://doi.org/10.1002/anie.200803611
https://doi.org/10.1002/anie.200803611
Publikováno v:
The Journal of Organic Chemistry. 74:289-297
A palladium-catalyzed, norbornene-mediated ortho-alkylation reaction of aryl iodides with secondary alkyl halides is described. Intermolecular or intramolecular ortho-alkylation proceeds in a domino process with various termination steps, generating
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c76c989795c4c8780601226f7c58e6c0
https://doi.org/10.1021/jo802180h
https://doi.org/10.1021/jo802180h
Autor:
Alena Rudolph, Walter H. Chan, Chris Dockendorff, Matthew J. Fleming, Helen A. McManus, Jérémy Ruiz, Mark Lautens
Publikováno v:
Chemistry - A European Journal. 14:2112-2124
New enantioselective syntheses of the B/C hexahydrobenzo[c]phenanthridine alkaloids (+)-homochelidonine, (+)-chelamidine, (+)-chelidonine, (+)-chelamine, and (+)-norchelidonine are described. Our rapid and convergent route to this class of natural pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b53fc69d0e4d7f98bbe958976ce5614
https://doi.org/10.1002/chem.200701775
https://doi.org/10.1002/chem.200701775
Publikováno v:
Journal of the American Chemical Society, 132(41), 14349-14351. AMER CHEMICAL SOC
Cu-TolBINAP-catalyzed conjugate addition of Grignard reagents to 4-chloro-α,β-unsaturated esters, thioesters, and ketones leads to 4-chloro-3-alkyl-substituted thioesters and ketones in up to 84% yield and up to 96% ee upon protonation of the corre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::934aa19686c26c928b9bdcaad8f53f2b
https://research.rug.nl/en/publications/d60c3b8f-b464-439b-82e3-3df1f20b9057
https://research.rug.nl/en/publications/d60c3b8f-b464-439b-82e3-3df1f20b9057
Autor:
Syuzanna R. Harutyunyan, Valentin Hornillos, Martín Fañanás-Mastral, Manuel Perez, Alena Rudolph, Pieter H. Bos, Ben L. Feringa
Publikováno v:
ChemInform. 44
A highly efficient, regio- and enantioselective Cu(I)/phosphoramidite-catalyzed asymmetric allylic alkylation of allyl ethers with organolithium reagents is reported (see scheme). The use of organolithium reagents is essential for this catalytic C-C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::02ce1d78e21ece46c30c5692368d3ffc
https://doi.org/10.1002/chin.201310021
https://doi.org/10.1002/chin.201310021