Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Alena Polášková"'
Autor:
Marie Brázdová, Vlastimil Tichý, Robert Helma, Pavla Bažantová, Alena Polášková, Aneta Krejčí, Marek Petr, Lucie Navrátilová, Olga Tichá, Karel Nejedlý, Martin L Bennink, Vinod Subramaniam, Zuzana Bábková, Tomáš Martínek, Matej Lexa, Matej Adámik
Publikováno v:
PLoS ONE, Vol 11, Iss 12, p e0167439 (2016)
Triplex DNA is implicated in a wide range of biological activities, including regulation of gene expression and genomic instability leading to cancer. The tumor suppressor p53 is a central regulator of cell fate in response to different type of insul
Externí odkaz:
https://doaj.org/article/b3f101886c88485e8b58765be1c7d627
Autor:
Lucie Holaňová, Pavla Bažantová, Petr Pečinka, Vlastimil Tichý, Lucie Navrátilová, Alena Polášková, Matej Adámik, Marie Brázdová
Publikováno v:
Biochemical and Biophysical Research Communications. 456:29-34
Site-specific DNA recognition and binding activity belong to common attributes of all three members of tumor suppressor p53 family proteins: p53, p63 and p73. It was previously shown that heavy metals can affect p53 conformation, sequence-specific bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ab54e99974425cb0d3cdee2a6e41653
https://doi.org/10.1016/j.bbrc.2014.11.027
https://doi.org/10.1016/j.bbrc.2014.11.027
Autor:
Matej Adámik, Marek Petr, Alena Polášková, Aneta Krejčí, Iva Kejnovská, Zuzana Dvořáková, Marie Brázdová, Lucie Navrátilová, Robert Helma, Michaela Vorlíčková
Publikováno v:
Bioscience Reports
We found that the p53 tumour suppressor protein binds specifically to the G-quadruplex DNA formed by MYC promoter sequence. We propose that p53 binding to G-quadruplexes can participate in regulation of p53 target genes.
G-quadruplexes are four-
G-quadruplexes are four-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de4c4051ec56c124219574646ce73352
https://doi.org/10.1042/bsr20160232
https://doi.org/10.1042/bsr20160232
Autor:
Martin L. Bennink, Robert Helma, Olga Tichá, Matej Lexa, Marek Petr, Pavla Bažantová, Marie Brázdová, Vinod Subramaniam, Karel Nejedlý, Lucie Navrátilová, Vlastimil Tichý, Aneta Krejčí, Matej Adámik, Tomáš Martínek, Alena Polášková, Zuzana Bábková
Publikováno v:
PLoS ONE, 11(12). Public Library of Science
PLoS ONE, Vol 11, Iss 12, p e0167439 (2016)
PLoS ONE, 11(12):e0167439. Public Library of Science
Brázdová, M, Tichý, V, Helma, R, Bažantová, P, Polášková, A, Krejčí, A, Petr, M, Navrátilová, L, Tichá, O, Nejedlý, K, Bennink, M L, Subramaniam, V, Bábková, Z, Martínek, T, Lexa, M & Adámik, M 2016, ' p53 Specifically Binds Triplex DNA In Vitro and in Cells ', PLoS ONE, vol. 11, no. 12, pp. e0167439 . https://doi.org/10.1371/journal.pone.0167439
PLoS ONE
PLoS ONE, Vol 11, Iss 12, p e0167439 (2016)
PLoS ONE, 11(12):e0167439. Public Library of Science
Brázdová, M, Tichý, V, Helma, R, Bažantová, P, Polášková, A, Krejčí, A, Petr, M, Navrátilová, L, Tichá, O, Nejedlý, K, Bennink, M L, Subramaniam, V, Bábková, Z, Martínek, T, Lexa, M & Adámik, M 2016, ' p53 Specifically Binds Triplex DNA In Vitro and in Cells ', PLoS ONE, vol. 11, no. 12, pp. e0167439 . https://doi.org/10.1371/journal.pone.0167439
PLoS ONE
Triplex DNA is implicated in a wide range of biological activities, including regulation of gene expression and genomic instability leading to cancer. The tumor suppressor p53 is a central regulator of cell fate in response to different type of insul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7f2d43b8fcd2cecf32bb44df522d265
https://doi.org/10.1371/journal.pone.0167439
https://doi.org/10.1371/journal.pone.0167439