Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Alena M. Langsjoen"'
Publikováno v:
The Permanente Journal. 23
CONTEXT Heart failure (HF) is rapidly increasing in incidence and is often present in patients receiving long-term statin therapy. OBJECTIVE To test whether or not patients with HF on long-term statin therapy respond to discontinuation of statin ther
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b1a261a895d07fcc3d0b42da0dcc495d
https://doi.org/10.7812/tpp/18.257
https://doi.org/10.7812/tpp/18.257
Publikováno v:
The Permanente journal. 23
CONTEXT: Heart failure (HF) is rapidly increasing in incidence and is often present in patients receiving long-term statin therapy. OBJECTIVE: To test whether or not patients with HF on long-term statin therapy respond to discontinuation of statin th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1c21343b7105d7b173920fe7e6804323
https://pubmed.ncbi.nlm.nih.gov/31496499
https://pubmed.ncbi.nlm.nih.gov/31496499
Autor:
Alena M. Langsjoen, Peter H. Langsjoen
Publikováno v:
Clinical Pharmacology in Drug Development. 3:13-17
The bioavailability of the reduced form of coenzyme Q10 (ubiquinol) was compared to oxidized coenzyme Q10 (ubiquinone) with identical soft gel capsule excipients by measuring steady state plasma coenzyme Q10 (CoQ10 ) levels in 12 healthy volunteers.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b6bad120116ad879580eb1a52d00e3c
https://doi.org/10.1002/cpdd.73
https://doi.org/10.1002/cpdd.73
Autor:
Tomohito Hamazaki, Alena M. Langsjoen, Peter H. Langsjoen, Tetsuyuki Kobayashi, Harumi Okuyama, Yoko Hashimoto, Satoshi Yoshida, Naoki Ohara
Publikováno v:
Pharmacology. 98(3-4)
Background: Positive associations have been observed between cardiovascular disease (CVD) and type 2 diabetes mellitus (DM), but their causal relationship has not been clarified. Nevertheless, guidelines from relevant medical societies recommend usin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5f14649dde7d6567c2218a5f7d62eb1
https://pubmed.ncbi.nlm.nih.gov/27251151
https://pubmed.ncbi.nlm.nih.gov/27251151
Autor:
Peter H. Langsjoen, Alena M. Langsjoen
Publikováno v:
BioFactors. 32:119-128
Patients with CHF, NYHA class IV, often fail to achieve adequate plasma CoQ10 levels on supplemental ubiquinone at dosages up to 900 mg/day. These patients often have plasma total CoQ10 levels of less than 2.5 microg/ml and have limited clinical impr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbe6154fc9fc49d491346bcf7846c02d
https://doi.org/10.1002/biof.5520320114
https://doi.org/10.1002/biof.5520320114
Publikováno v:
BioFactors. 25:147-152
Fifty consecutive new cardiology clinic patients who were on statin drug therapy (for an average of 28 months) on their initial visit were evaluated for possible adverse statin effects (myalgia, fatigue, dyspnea, memory loss, and peripheral neuropath
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a89e94ca370934c02a833e57a2828ea
https://doi.org/10.1002/biof.5520250116
https://doi.org/10.1002/biof.5520250116
Autor:
Peter H. Langsjoen, Alena M. Langsjoen
Publikováno v:
The Asia Pacific Heart Journal. 7:160-168
The vitamin-like nutrient CoQ 10 (ubiquinone), discovered in 1957 and first used in human illness in 1967, has a crucial role in cellular ATP production as the coenzyme for mitochondrial complexes I, II and III. CoQ 10 is also a lipid soluble antioxi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d4ae50fef7513af7473323e8b30024b7
https://doi.org/10.1016/s1328-0163(98)90022-7
https://doi.org/10.1016/s1328-0163(98)90022-7
Autor:
Peter H, Langsjoen, Alena M, Langsjoen
Publikováno v:
Clinical pharmacology in drug development. 3(1)
The bioavailability of the reduced form of coenzyme Q10 (ubiquinol) was compared to oxidized coenzyme Q10 (ubiquinone) with identical soft gel capsule excipients by measuring steady state plasma coenzyme Q10 (CoQ10 ) levels in 12 healthy volunteers.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ada66305767f7bec7c816a5df34a45fb
https://pubmed.ncbi.nlm.nih.gov/27128225
https://pubmed.ncbi.nlm.nih.gov/27128225
Autor:
Peter H. Langsjoen, Alena M. Langsjoen
Publikováno v:
BioFactors (Oxford, England). 18(1-4)
The depletion of the essential nutrient CoQ10 by the increasingly popular cholesterol lowering drugs, HMG CoA reductase inhibitors (statins), has grown from a level of concern to one of alarm. With ever higher statin potencies and dosages, and with a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54d1b948b0d2eac4fb9810de0a11cd92
https://pubmed.ncbi.nlm.nih.gov/14695925
https://pubmed.ncbi.nlm.nih.gov/14695925
Autor:
Alena M. Langsjoen, Peter H. Langsjoen
Publikováno v:
BioFactors (Oxford, England). 9(2-4)
The clinical experience in cardiology with CoQ10 includes studies on congestive heart failure, ischemic heart disease, hypertensive heart disease, diastolic dysfunction of the left ventricle, and reperfusion injury as it relates to coronary artery by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58114d81ecf3abff5952cf0de2447cfc
https://pubmed.ncbi.nlm.nih.gov/10416041
https://pubmed.ncbi.nlm.nih.gov/10416041