Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Alena Karpusenko"'
Autor:
Robert Riehn, Shuang Fang Lim, Carlos Ortiz, Preston Countryman, Maedeh Roushan, Hong Wang, Alena Karpusenko, Parminder Kaur
Publikováno v:
Biomicrofluidics. 8(3)
We present an analytic technique for probing protein-catalyzed transient DNA loops that is based on nanofluidic channels. In these nanochannels, DNA is forced in a linear configuration that makes loops appear as folds whose size can easily be quantif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c7e4735c9b894c43c6e5caeb94ef6c2
https://pubmed.ncbi.nlm.nih.gov/25379073
https://pubmed.ncbi.nlm.nih.gov/25379073
Autor:
Joshua H. Carpenter, Alena Karpusenko, Junhan Pan, Robert Riehn, Chunda Zhou, Shuang Fang Lim
Publikováno v:
Journal of applied physics. 111(2)
We report an experimental investigation of the magnitude of length and density fluctuations in DNA that has been stretched in nanofluidic channels. We find that the experimental data can be described using a one-dimensional overdamped oscillator chai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abb2dfb7207e564d367f0db5178b8d04
https://pubmed.ncbi.nlm.nih.gov/22312183
https://pubmed.ncbi.nlm.nih.gov/22312183
Publikováno v:
Biomicrofluidics. 7:064105
We report the simultaneous mapping of multiple histone tail modifications on chromatin that has been confined to nanofluidic channels. In these channels, chromatin is elongated, and histone modification can be detected using fluorescently tagged mono
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4b75f7c4a686042f81144e6ddf91977
https://doi.org/10.1063/1.4833257
https://doi.org/10.1063/1.4833257
Autor:
Shuang Fang Lim, Tyra A. Lamar, Joseph A. Hook, Alena Karpusenko, John J. Sakon, Robert Riehn
Publikováno v:
Biomicrofluidics. 5:034106
We report the profiling of the 5-methyl cytosine distribution within single genomic-sized DNA molecules at a gene-relevant resolution. This method linearizes and stretches DNA molecules by confinement to channels with a dimension of about 250×200 nm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb0d8462cd44c74dc2dd474789805024
https://doi.org/10.1063/1.3613671
https://doi.org/10.1063/1.3613671
Publikováno v:
Applied Physics Letters. 98:253704
DNA confined to rigid nanotubes shows density fluctuations around its stretched equilibrium conformation. We report an experimental investigation of the length-scale dependent dynamics of these density fluctuations. We find that for highly elongated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3956b5921275527e2a74aa21149bda43
https://doi.org/10.1063/1.3602922
https://doi.org/10.1063/1.3602922