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of 3
pro vyhledávání: '"Alena Drobiazko"'
Autor:
Aleksandr Andriianov, Silvia Trigüis, Alena Drobiazko, Nicolas Sierro, Nikolai V. Ivanov, Maria Selmer, Konstantin Severinov, Artem Isaev
Publikováno v:
Cell Reports, Vol 42, Iss 8, Pp 112972- (2023)
Summary: Bacteriophage T3 encodes a SAMase that, through cleavage of S-adenosyl methionine (SAM), circumvents the SAM-dependent type I restriction-modification (R-M) defense. We show that SAMase also allows T3 to evade the BREX defense. Although SAM
Externí odkaz:
https://doaj.org/article/a2b2ebd74e704a3d81f06bcecb7623d6
Autor:
Aleksandr Andriianov, Silvia Triguis, Alena Drobiazko, Nicolas Sierro, Nikolai V. Ivanov, Maria Selmer, Konstantin Severinov, Artem Isaev
Bacteriophage T3 encodes a SAMase that through cleavage of S-adenosyl-methionine (SAM) circumvents the SAM-dependent Type I Restriction-Modification defence of the host bacteriumEscherichia coli. Here, we show that the SAMase also allows T3 to evade
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d3fa4607b69c46d9c004bf629f3334b3
https://doi.org/10.1101/2023.02.27.530186
https://doi.org/10.1101/2023.02.27.530186
Autor:
Alena Drobiazko, Nicolas Sierro, Konstantin Severinov, Artem Isaev, Udi Qimron, Julia Gordeeva, Ido Yosef, Nikolai V. Ivanov
Publikováno v:
Nucleic Acids Research
BREX (for BacteRiophage EXclusion) is a superfamily of common bacterial and archaeal defence systems active against diverse bacteriophages. While the mechanism of BREX defence is currently unknown, self versus non-self differentiation requires methyl