Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Alena A. Semenova"'
Autor:
Mikhail V. Dubinin, Irina B. Mikheeva, Anastasia E. Stepanova, Anastasia D. Igoshkina, Alena A. Cherepanova, Alena A. Semenova, Vyacheslav A. Sharapov, Igor I. Kireev, Konstantin N. Belosludtsev
Publikováno v:
Biomolecules, Vol 14, Iss 3, p 316 (2024)
Duchenne muscular dystrophy is caused by loss of the dystrophin protein. This pathology is accompanied by mitochondrial dysfunction contributing to muscle fiber instability. It is known that mitochondria-targeted in vivo therapy mitigates pathology a
Externí odkaz:
https://doaj.org/article/5147bebf625f44df8404ef6370119d83
Autor:
Mikhail V. Dubinin, Darya A. Nedopekina, Anna I. Ilzorkina, Alena A. Semenova, Vyacheslav A. Sharapov, Eldar V. Davletshin, Natalia V. Mikina, Yuri P. Belsky, Anna Yu. Spivak, Vladimir S. Akatov, Natalia V. Belosludtseva, Jiankang Liu, Konstantin N. Belosludtsev
Publikováno v:
Membranes, Vol 13, Iss 6, p 563 (2023)
The present work shows the cytotoxic effects of novel conjugates of ursolic, oleanolic, maslinic, and corosolic acids with the penetrating cation F16 on cancer cells (lung adenocarcinoma A549 and H1299, breast cancer cell lines MCF-7 and BT474) and n
Externí odkaz:
https://doaj.org/article/e339fd2e58c7473da384490b7ffb9826
Autor:
Victor N. Samartsev, Ekaterina I. Khoroshavina, Evgeniya K. Pavlova, Mikhail V. Dubinin, Alena A. Semenova
Publikováno v:
Membranes, Vol 13, Iss 5, p 472 (2023)
It is now generally accepted that the role of bile acids in the organism is not limited to their participation in the process of food digestion. Indeed, bile acids are signaling molecules and being amphiphilic compounds, are also capable of modifying
Externí odkaz:
https://doaj.org/article/6580ab385ecb461d9200c9ea46e56c0b
Autor:
Mikhail V. Dubinin, Vyacheslav A. Sharapov, Alena A. Semenova, Lyudmila V. Parfenova, Anna I. Ilzorkina, Ekaterina I. Khoroshavina, Natalia V. Belosludtseva, Sergey V. Gudkov, Konstantin N. Belosludtsev
Publikováno v:
Membranes, Vol 12, Iss 9, p 866 (2022)
This paper demonstrates the membranotropic effect of modified levopimaric acid diene adducts on liver mitochondria and lecithin liposomes. We found that the derivatives dose-dependently reduced the efficiency of oxidative phosphorylation of mitochond
Externí odkaz:
https://doaj.org/article/dc620596d2484e668b44ca3d44c14494
Autor:
Natalia V. Belosludtseva, Vlada S. Starinets, Alena A. Semenova, Anastasia D. Igoshkina, Mikhail V. Dubinin, Konstantin N. Belosludtsev
Publikováno v:
Biology, Vol 11, Iss 3, p 380 (2022)
S-15176 difumarate salt, a derivative of the anti-ischemic metabolic drug trimetazidine, has been intensively studied for its impact on cellular metabolism in animal models of ischemia-reperfusion injury of the liver, heart, spinal cord, and other or
Externí odkaz:
https://doaj.org/article/ea188c6812934d85b5ada3f33ff0f63a
Autor:
Mikhail V. Dubinin, Alena A. Semenova, Darya A. Nedopekina, Eldar V. Davletshin, Anna Yu. Spivak, Konstantin N. Belosludtsev
Publikováno v:
Membranes, Vol 11, Iss 5, p 352 (2021)
This work demonstrates the effects of a newly synthesized conjugate of the plant triterpenoid betulin and the penetrating cation F16 used for mitochondrial targeting. The resulting F16-betulin conjugate revealed a mitochondria-targeted effect, decrea
Externí odkaz:
https://doaj.org/article/858a1a5832f24a6fb636b50da2395e68
Publikováno v:
CardioSomatics. 13:184-191
Objective. We aimed to assess the psychological state and personality-adaptive potential in patients with Takotsubo syndrome (TS), and to use the results to construct a prognostic model for the risk of developing the disease. Materials and methods. A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d6bc6a88e4bed28dfd92d225ecadc83
https://doi.org/10.17816/cs200183
https://doi.org/10.17816/cs200183
Publikováno v:
Biochemical and Biophysical Research Communications. 606:163-167
The present work shows that the rate of free respiration of liver mitochondria (in the absence of ATP synthesis (state 4) during the oxidation of succinate is 1.7 times higher than during the oxidation of glutamate with malate. In turn, in the case o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b37903642671ac3b53c21497f96ef144
https://doi.org/10.1016/j.bbrc.2022.03.099
https://doi.org/10.1016/j.bbrc.2022.03.099
Publikováno v:
Biochemistry (Moscow), Supplement Series A: Membrane and Cell Biology. 15:156-166
This study examines the effect of glucocorticoid deflazacort on the functioning of rat liver mitochondria. Deflazacort at concentrations up to 100 μM has been shown to have no effect on respiration and oxidative phosphorylation of rat liver mitochon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d349284a6d8f3455bc1b0ffbc250a13
https://doi.org/10.1134/s1990747821020033
https://doi.org/10.1134/s1990747821020033
Publikováno v:
Biochimie. 181:215-225
The paper shows that natural α,ω-dioic acid, α,ω-hexadecanedioic acid (HDA), is able to stimulate the respiration of succinate-fueled rat liver mitochondria in state 4 without induction of proton conductivity of the inner membrane. This effect of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d126192bd91606775bf1fc59c70777ef
https://doi.org/10.1016/j.biochi.2020.12.021
https://doi.org/10.1016/j.biochi.2020.12.021