Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Alen Trubelja"'
Autor:
Gang Bao, Alen Trubelja
Publikováno v:
Extreme Mechanics Letters. 20:91-98
Living cells can sense mechanical forces or deformation, and convert them into biological responses. However, although many details of mechanical, chemical and biological interactions in cells have emerged over the past few decades, the exact molecul
Autor:
Daniel A. Hammer, Ann C. Gaffey, Zhichun Wang, Alen Trubelja, Pavan Atluri, Jason A. Burdick, Janna N. Sloand, Leo L. Wang, Chantel M. Venkataraman
Publikováno v:
Biomacromolecules. 18:77-86
While siRNA has tremendous potential for therapeutic applications, advancement is limited by poor delivery systems. Systemically, siRNAs are rapidly degraded, may have off-target silencing, and necessitate high working concentrations. To overcome thi
Autor:
Chantel M. Venkataraman, Ann C. Gaffey, Susan M. Schultz, Pavan Atluri, Alen Trubelja, Minna H. Chen, Jason A. Burdick, Chandra M. Sehgal, Jennifer J. Chung, Carol W. Chen
Publikováno v:
J Thorac Cardiovasc Surg
Objectives The ventricle undergoes adverse remodeling after myocardial infarction, resulting in abnormal biomechanics and decreased function. We hypothesize that tissue-engineered therapy could minimize postischemic remodeling through mechanical stre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94a45b1324439b88045471de78b10679
https://europepmc.org/articles/PMC7769598/
https://europepmc.org/articles/PMC7769598/
Autor:
George Hung, Anderson H. Ta, Ann C. Gaffey, Jason J. Han, Samantha J. Paulsen, Patrick V. Dinh, Renganaden Sooppan, Jordan S. Miller, Alen Trubelja, Chantel M. Venkataraman, Pavan Atluri
Publikováno v:
ResearcherID
The field of tissue engineering has advanced the development of increasingly biocompatible materials to mimic the extracellular matrix of vascularized tissue. However, a majority of studies instead rely on a multiday inosculation between engineered v
Autor:
Y. Joseph Woo, Alen Trubelja, Nimesh D. Desai, John R. Frederick, Wilson Y. Szeto, Joseph E. Bavaria, Alberto Pochettino, Elaine Yang
Publikováno v:
The Annals of Thoracic Surgery. 95:1808-1811
Femoral and axillary cannulation for arterial inflow in acute type A aortic dissection are the most commonly used cannulation strategies in current practice. More recently, our group and others have successfully used a central cannulation technique w
Autor:
R. Michael Greiwe, Comron Saifi, Christopher S. Ahmad, Charlie Yongpravat, Alen Trubelja, William N. Levine, Louis U. Bigliani, Thomas R. Gardner, Jonathan D. Lester
Publikováno v:
Journal of Shoulder and Elbow Surgery. 22:122-128
The relationships between reaming parameters for glenoid-implant surface area and bone loss in total shoulder arthroplasty have not been well established. The hypotheses of this study are: (1) for large version corrections, a large reaming depth of 5
Autor:
Ann C Gaffey, Minna H Chen, Alen Trubelja, Chantel M Venkataraman, Carol W Chen, Susan S, Chandra M Sehgal, Jason A Burdick, Pavan Atluri
Publikováno v:
Circulation. 132
The ventricle undergoes adverse remodeling, post-infarction. We developed an injectable shear-thinning hyaluronic acid hydrogel(STG) and endothelial progenitor cell construct(STG-EPC) to enhance vasculogenesis(shown previously) and mechanically stabi
Autor:
Renganaden V. Soopan, George Hung, Ann C. Gaffey, Chantel M. Venkataraman, Minna H. Chen, Christopher B. Rodell, Patrick V. Dinh, Jason A. Burdick, John W. MacArthur, Pavan Atluri, Alen Trubelja
Publikováno v:
The Journal of thoracic and cardiovascular surgery. 150(5)
The clinical translation of cell-based therapies for ischemic heart disease has been limited because of low cell retention (1%) within, and poor targeting to, ischemic myocardium. To address these issues, we developed an injectable hyaluronic acid (H
Publikováno v:
Journal of The Royal Society Interface. 14(131):20170137
Cancer remains one of the leading causes of death, albeit enormous efforts to cure the disease. To overcome the major challenges in cancer therapy, we need to have a better understanding of the tumour microenvironment (TME), as well as a more effecti
Autor:
Jason A. Burdick, Bryan B. Edwards, George Hung, Pavan Atluri, John W. MacArthur, Yasuhiro Shudo, Kenneth B. Margulies, Christopher Brusalis, Alexander S. Fairman, Y. Joseph Woo, Brendan P. Purcell, Mollie S. Davis, Anbin Mu, Jay Patel, William Hiesinger, Jeffrey E. Cohen, Alen Trubelja
Publikováno v:
Circulation. Heart failure. 7(4)
Background— Neuregulin-1β (NRG) is a member of the epidermal growth factor family possessing a critical role in cardiomyocyte development and proliferation. Systemic administration of NRG demonstrated efficacy in cardiomyopathy animal models, lead