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PGC-1α agonism induces fetal hemoglobin and exerts antisickling effects in sickle cell disease.

Autor: Sun Y; Section of Hematology-Medical Oncology, Department of Medicine, Boston Medical Center, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA., Benmhammed H; Section of Hematology-Medical Oncology, Department of Medicine, Boston Medical Center, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA., Al Abdullatif S; Single Cell Sequencing Core Facility, Department of Medicine, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA., Habara A; Imam Abdulrahman Bin Faisal University, Department of Clinical Biochemistry, Dammam, Saudi Arabia., Fu E; Sargent College of Health and Rehabilitation Sciences, Boston University, Boston, MA, USA., Brady J; Sargent College of Health and Rehabilitation Sciences, Boston University, Boston, MA, USA., Williams C; Single Cell Sequencing Core Facility, Department of Medicine, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA., Ilinski A; Section of Hematology-Medical Oncology, Department of Medicine, Boston Medical Center, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA., Sharma A; Section of Hematology-Medical Oncology, Department of Medicine, Boston Medical Center, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA., Mahdaviani K; Section of Hematology-Medical Oncology, Department of Medicine, Boston Medical Center, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA., Alekseyev YO; Department of Pathology and Laboratory Medicine, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA., Campbell JD; Division of Computational Biomedicine, Department of Medicine, Boston Medical Center, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA., Steinberg MH; Section of Hematology-Medical Oncology, Department of Medicine, Boston Medical Center, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA., Cui S; Section of Hematology-Medical Oncology, Department of Medicine, Boston Medical Center, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA.

Publikováno v: Science advances [Sci Adv] 2024 Aug 02; Vol. 10 (31), pp. eadn8750. Date of Electronic Publication: 2024 Jul 31.

Transmission Dynamics and Rare Clustered Transmission Within an Urban University Population Before Widespread Vaccination.

Autor: Turcinovic J; Department of Virology, Immunology, and Microbiology, Chobanian & Avedisian School of Medicine.; National Emerging Infectious Diseases Laboratories.; Program in Bioinformatics., Kuhfeldt K; Student Health Services., Sullivan M; Student Health Services., Landaverde L; Department of Biomedical Engineering.; Precision Diagnostics Center.; BU Clinical Testing Laboratory, Research Department., Platt JT; Student Health Services., Alekseyev YO; Department of Pathology and Laboratory Medicine., Doucette-Stamm L; BU Clinical Testing Laboratory, Research Department., Hamer DH; National Emerging Infectious Diseases Laboratories.; Precision Diagnostics Center.; Department of Global Health, School of Public Health.; Section of Infectious Disease, Department of Medicine, Chobanian & Avedisian School of Medicine.; Center for Emerging Infectious Disease Policy and Research, Boston University, Massachusetts., Klapperich C; Department of Biomedical Engineering.; Precision Diagnostics Center.; BU Clinical Testing Laboratory, Research Department., Landsberg HE; Student Health Services., Connor JH; Department of Virology, Immunology, and Microbiology, Chobanian & Avedisian School of Medicine.; National Emerging Infectious Diseases Laboratories.; Program in Bioinformatics.; Center for Emerging Infectious Disease Policy and Research, Boston University, Massachusetts.

Publikováno v: The Journal of infectious diseases [J Infect Dis] 2024 Feb 14; Vol. 229 (2), pp. 485-492.

Heat Inactivation of Nipah Virus for Downstream Single-Cell RNA Sequencing Does Not Interfere with Sample Quality.

Autor: Hume AJ; Department of Virology, Immunology and Microbiology, Chobanian & Avedisian School of Medicine, Boston University, Boston, MA 02118, USA.; National Emerging Infectious Diseases Laboratories, Boston University, Boston, MA 02218, USA., Olejnik J; Department of Virology, Immunology and Microbiology, Chobanian & Avedisian School of Medicine, Boston University, Boston, MA 02118, USA.; National Emerging Infectious Diseases Laboratories, Boston University, Boston, MA 02218, USA., White MR; Department of Virology, Immunology and Microbiology, Chobanian & Avedisian School of Medicine, Boston University, Boston, MA 02118, USA.; National Emerging Infectious Diseases Laboratories, Boston University, Boston, MA 02218, USA., Huang J; Center for Regenerative Medicine of Boston University and Boston Medical Center, Boston, MA 02118, USA.; The Pulmonary Center and Department of Medicine, Chobanian & Avedisian School of Medicine, Boston University, Boston, MA 02118, USA., Turcinovic J; Department of Virology, Immunology and Microbiology, Chobanian & Avedisian School of Medicine, Boston University, Boston, MA 02118, USA.; National Emerging Infectious Diseases Laboratories, Boston University, Boston, MA 02218, USA., Heiden B; Department of Virology, Immunology and Microbiology, Chobanian & Avedisian School of Medicine, Boston University, Boston, MA 02118, USA.; National Emerging Infectious Diseases Laboratories, Boston University, Boston, MA 02218, USA., Bawa PS; Center for Regenerative Medicine of Boston University and Boston Medical Center, Boston, MA 02118, USA., Williams CJ; Department of Medicine, Single Cell Sequencing Core Facility, Chobanian & Avedisian School of Medicine, Boston University, Boston, MA 02118, USA., Gorham NG; Microarray and Sequencing Resource Core Facility, Chobanian & Avedisian School of Medicine, Boston University, Boston, MA 02118, USA., Alekseyev YO; Department of Pathology and Laboratory Medicine, Chobanian & Avedisian School of Medicine, Boston University, Boston, MA 02118, USA., Connor JH; Department of Virology, Immunology and Microbiology, Chobanian & Avedisian School of Medicine, Boston University, Boston, MA 02118, USA.; National Emerging Infectious Diseases Laboratories, Boston University, Boston, MA 02218, USA., Kotton DN; Center for Regenerative Medicine of Boston University and Boston Medical Center, Boston, MA 02118, USA.; The Pulmonary Center and Department of Medicine, Chobanian & Avedisian School of Medicine, Boston University, Boston, MA 02118, USA., Mühlberger E; Department of Virology, Immunology and Microbiology, Chobanian & Avedisian School of Medicine, Boston University, Boston, MA 02118, USA.; National Emerging Infectious Diseases Laboratories, Boston University, Boston, MA 02218, USA.

Publikováno v: Pathogens (Basel, Switzerland) [Pathogens] 2024 Jan 09; Vol. 13 (1). Date of Electronic Publication: 2024 Jan 09.