Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Aleksey Y. Ogurtsov"'
Autor:
Jung-Hyun Kim, Vladimir N. Noskov, Aleksey Y. Ogurtsov, Ramaiah Nagaraja, Nikolai Petrov, Mikhail Liskovykh, Brian P. Walenz, Hee-Sheung Lee, Natalay Kouprina, Adam M. Phillippy, Svetlana A. Shabalina, David Schlessinger, Vladimir Larionov
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract The rDNA clusters and flanking sequences on human chromosomes 13, 14, 15, 21 and 22 represent large gaps in the current genomic assembly. The organization and the degree of divergence of the human rDNA units within an individual nucleolar or
Externí odkaz:
https://doaj.org/article/3fe958d0148f47c1a2f569bdf90256d7
Autor:
Roger Karlsson, Francisco Salvà-Serra, Aleksey Y. Ogurtsov, Björn Andersson, Edward R. B. Moore, Beatriz Piñeiro-Iglesias, Gelio Alves, Daniel Jaén-Luchoro, Yi-Kuo Yu
Publikováno v:
Journal of the American Society for Mass Spectrometry. 33(6)
Fast and accurate identifications of pathogenic bacteria along with their associated antibiotic resistance proteins are of paramount importance for patient treatments and public health. While mass spectrometry has become an important, technique for d
Autor:
N. S. Petrov, Aleksey Y. Ogurtsov, Natalay Kouprina, Vladimir N. Noskov, David Schlessinger, Hee-Sheung Lee, Jung-Hyun Kim, Adam M. Phillippy, Ramaiah Nagaraja, Svetlana A. Shabalina, Vladimir Larionov, Mikhail Liskovykh, Brian P. Walenz
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Scientific Reports
Scientific Reports
The rDNA clusters and flanking sequences on human chromosomes 13, 14, 15, 21 and 22 represent large gaps in the current genomic assembly. The organization and the degree of divergence of the human rDNA units within an individual nucleolar organizer r
Autor:
Yulan Piao, Sergey Koren, Vladimir N. Noskov, Alexander T. Dilthey, Aleksey Y. Ogurtsov, Dawood B. Dudekula, Hee-Sheung Lee, Svetlana A. Shabalina, Adam M. Phillippy, Ramaiah Nagaraja, Vladimir Larionov, Koichi Utani, Jung-Hyun Kim, William H. Wood, David Schlessinger
Publikováno v:
Nucleic Acids Research
Despite the key role of the human ribosome in protein biosynthesis, little is known about the extent of sequence variation in ribosomal DNA (rDNA) or its pre-rRNA and rRNA products. We recovered ribosomal DNA segments from a single human chromosome 2
Autor:
Maxim Panov, Aleksey Y. Ogurtsov, Svetlana A. Shabalina, Ekaterina Savitskaya, Konstantin Severinov, Eugene V. Koonin, Bogdan Kirillov
Publikováno v:
Nucleic Acids Research
The choice of guide RNA (gRNA) for CRISPR-based gene targeting is an essential step in gene editing applications, but the prediction of gRNA specificity remains challenging. Lack of transparency and focus on point estimates of efficiency disregarding
Publikováno v:
PLoS ONE, Vol 5, Iss 11, p e15438 (2010)
Statistically meaningful comparison/combination of peptide identification results from various search methods is impeded by the lack of a universal statistical standard. Providing an E-value calibration protocol, we demonstrated earlier the feasibili
Externí odkaz:
https://doaj.org/article/c79557b80eac40259ae1b6f2bf3452da
Autor:
Olga V Matveeva, Yibin Kang, Alexey N Spiridonov, Pål Saetrom, Vladimir A Nemtsov, Aleksey Y Ogurtsov, Yury D Nechipurenko, Svetlana A Shabalina
Publikováno v:
PLoS ONE, Vol 5, Iss 4, p e10180 (2010)
Prediction of efficient oligonucleotides for RNA interference presents a serious challenge, especially for the development of genome-wide RNAi libraries which encounter difficulties and limitations due to ambiguities in the results and the requiremen
Externí odkaz:
https://doaj.org/article/3bdd37aa3d8642e8967042a48e66be12
Autor:
Aleksey Y Ogurtsov, Leonardo Mariño-Ramírez, Gibbes R Johnson, David Landsman, Svetlana A Shabalina, Nikolay A Spiridonov
Publikováno v:
PLoS ONE, Vol 3, Iss 10, p e3599 (2008)
BACKGROUND:Protein kinase (PK) genes comprise the third largest superfamily that occupy approximately 2% of the human genome. They encode regulatory enzymes that control a vast variety of cellular processes through phosphorylation of their protein su
Externí odkaz:
https://doaj.org/article/891bd63b9a204b9e9801bff78c9155e2
Publikováno v:
Proteomics
Mass spectrometry-based proteomics starts with identifications of peptides and proteins, which provide the bases for forming the next-level hypotheses whose "validations" are often employed for forming even higher level hypotheses and so forth. Scien
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3789cd20d2d856e13e26d4bcc44b8f3e
https://europepmc.org/articles/PMC6635056/
https://europepmc.org/articles/PMC6635056/
Autor:
Svetlana A. Shabalina, Olga V. Matveeva, Yury D. Nechipurenko, Nafisa N. Nazipova, Aleksey Y. Ogurtsov, Evgeniy Riabenko, Chikako Ragan
Publikováno v:
Bioinformatics. 32:i552-i558
Motivation: Target-specific hybridization depends on oligo-probe characteristics that improve hybridization specificity and minimize genome-wide cross-hybridization. Interplay between specific hybridization and genome-wide cross-hybridization has bee