Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Aleksey V. Belyaev"'
Publikováno v:
Biomechanics and Modeling in Mechanobiology. 22:785-808
Autor:
Aleksey V Belyaev
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0183093 (2017)
Isolation of microparticles and biological cells from mixtures and suspensions is a central problem in a variety of biomedical applications. This problem, for instance, is of an immense importance for microfluidic devices manipulating with whole bloo
Externí odkaz:
https://doaj.org/article/e433d6f98c394e9083a9bad25e2e9675
Autor:
Aleksey V. Belyaev
Publikováno v:
Biophys J
The largest blood glycoprotein von Willebrand factor (VWF) responds to hydrodynamic stresses in the bloodstream with abrupt conformation changes, thus increasing its adhesivity to platelets and collagen. Arterial and microvascular hemostasis relies o
Autor:
Daria O Yurkova, Simone Melchionna, Emeline Laborie, Olivier Languin-Cattoën, Fabio Sterpone, Philippe Derreumaux, Aleksey V. Belyaev
Publikováno v:
Polymers
Volume 13
Issue 22
Polymers, Vol 13, Iss 3912, p 3912 (2021)
Volume 13
Issue 22
Polymers, Vol 13, Iss 3912, p 3912 (2021)
Von Willebrand Factor (vWf) is a giant multimeric extracellular blood plasma involved in hemostasis. In this work we present multi-scale simulations of its three-domains fragment A1A2A3. These three domains are essential for the functional regulation
Autor:
Aleksey V. Belyaev
Publikováno v:
Russian Journal of Numerical Analysis and Mathematical Modelling. 34:241-251
Hemostasis is one of the most important protective mechanisms that functions to maintain vascular integrity and prevent bleeding. In arterial and microvascular circulation, where the near-wall shear stress is relatively high, the hemostatic response
Autor:
M. A. Kaznacheev, Aleksey V. Belyaev
Publikováno v:
Moscow University Physics Bulletin. 74:400-406
Blood platelets play a key role in hemostasis and thrombosis. In the present work, a mathematical model of adhesive interaction between a non-activated platelet and an adhesive substrate is proposed. The cell is represented as a solid non-deformable
Publikováno v:
Physics of Fluids. 34:049902
Autor:
Aleksey V. Belyaev, Jonathan M. Gibbins, Mikhail A. Panteleev, Vitaly Volpert, Joanne L. Dunster
Publikováno v:
Physics of Life Reviews. :116-119
Publikováno v:
Biochemistry (Moscow), Supplement Series A: Membrane and Cell Biology. 12:315-326
Platelets are unique cells of human body: they lack nucleus, are rather small in size (1–2 μm) and involved in several physiological functions, including hemostasis, immunity and angiogenesis. Platelets play a key role in the initiation of thrombo
Publikováno v:
Physics of Fluids. 33:093314
Aneurysms of saccular shape are usually associated with a slow, almost stagnant blood flow, as well as a consequent emergence of blood clots. Despite the practical importance, there is a lack of computational models that could combine platelet aggreg