Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Aleksey Chudnovskiy"'
Autor:
Moritz Wildgruber, Hakho Lee, Aleksey Chudnovskiy, Tae-Jong Yoon, Martin Etzrodt, Mikael J Pittet, Matthias Nahrendorf, Kevin Croce, Peter Libby, Ralph Weissleder, Filip K Swirski
Publikováno v:
PLoS ONE, Vol 4, Iss 5, p e5663 (2009)
Monocytes are circulating macrophage and dendritic cell precursors that populate healthy and diseased tissue. In humans, monocytes consist of at least two subsets whose proportions in the blood fluctuate in response to coronary artery disease, sepsis
Externí odkaz:
https://doaj.org/article/b8875df223a04622b898f2891ff108ba
Autor:
Sandra Nakandakari-Higa, Maria C. C. Canesso, Sarah Walker, Aleksey Chudnovskiy, Johanne T. Jacobsen, Jana Bilanovic, S. Martina Parigi, Karol Fiedorczuk, Elaine Fuchs, Angelina M. Bilate, Giulia Pasqual, Daniel Mucida, Yuri Pritykin, Gabriel D. Victora
Publikováno v:
bioRxiv
Cellular interactions are essential for tissue organization and functionality. In particular, immune cells rely on direct and usually transient interactions with other immune and non-immune populations to specify and regulate their function. To study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb5a34e0688be1fb7ea6d4286752e337
https://europepmc.org/articles/PMC10055214/
https://europepmc.org/articles/PMC10055214/
Proximity-dependent labeling identifies dendritic cells that prime the antitumor CD4+T cell response
Autor:
Aleksey Chudnovskiy, Sandra Nakandakari-Higa, Tiago BR Castro, Ang Cui, Chia-Hao Lin, Moshe Sade-Feldman, Brooke K. Phillips, Juhee Pae, Luka Mesin, Juliana Bortolatto, Lawrence D. Schweitzer, Giulia Pasqual, Li-Fan Lu, Nir Hacohen, Gabriel D. Victora
Dendritic cells (DCs) are uniquely capable of transporting tumoral antigens to tumor-draining lymph nodes (tdLNs), where they initiate antitumor immunity and mediate checkpoint blockade immunotherapy. Despite recent advances, the full phenotype of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::513747a094f78b3aeb1a979d91a2188e
https://doi.org/10.1101/2022.10.25.513771
https://doi.org/10.1101/2022.10.25.513771
Autor:
Gabriel Victora, Aleksey Chudnovskiy, Sandra Nakandakari-Higa, Tiago de Castro, Ang Cui, Chia-Hao Lin, Moshe Sade-Feldman, Brooke Phillips, Juhee Pae, Luka Mesin, Juliana Bortolatto, Lawrence Schweitzer, Giulia Pasqual, Li-Fan Lu, Nir Hacohen
Dendritic cells (DCs) are uniquely capable of transporting tumoral antigens to tumor-draining lymph nodes (tdLNs), where they initiate antitumor immunity and mediate checkpoint blockade immunotherapy. Despite recent advances, the full phenotype of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb2d7ca5ee420c9874c16103b377bbe3
https://doi.org/10.21203/rs.3.rs-2152423/v1
https://doi.org/10.21203/rs.3.rs-2152423/v1
Autor:
Thomas U. Marron, Sourav Ghosh, Raja M. Flores, Natalie Roy D’Amore, Boris Reizis, Margaret E. Kirkling, Andrew Leader, Laura Walker, Barbara Maier, Navpreet Tung, Nina Bhardwaj, Jessica LeBerichel, Christie Chang, Shrisha Maskey, John P. Finnigan, Andrea S. Wolf, Ephraim Kenigsberg, Aleksey Chudnovskiy, Miriam Merad, Steven T. Chen, Brian D. Brown, Adeeb Rahman, Carla V. Rothlin
Publikováno v:
Nature. 580:257-262
Checkpoint blockade therapies have improved cancer treatment, but such immunotherapy regimens fail in a large subset of patients. Conventional type 1 dendritic cells (DC1s) control the response to checkpoint blockade in preclinical models and are ass
Publikováno v:
Curr Opin Immunol
Antigen presentation is the key first step in the establishment of an antigen-specific T cell response. Among professional antigen presenting cells (APCs), dendritic cells (DCs) are the major population responsible for the priming of both CD4(+) and
Autor:
Abolfozl Arab, Norihiro Yamaguchi, Benjamin N. Ostendorf, Lou Baudrier, Aleksey Chudnovskiy, Bernardo Tavora, Benjamin Prizer, Hani Goodarzi, Elisa de Stanchina, Xiphias Ge Zhu, Rebecca C. Timson, Kıvanç Birsoy, Henrik Molina, Søren Heissel, Yuyang Liu, Gabriel D. Victora
Publikováno v:
Cell Metab
Summary Pancreatic ductal adenocarcinoma (PDAC) cells require substantial metabolic rewiring to overcome nutrient limitations and immune surveillance. However, the metabolic pathways necessary for pancreatic tumor growth in vivo are poorly understood
Autor:
Lawrence D. Schweitzer, Jeroen M. J. Tas, Marianna Agudelo, Giulia Pasqual, Ang Cui, Nir Hacohen, Aleksey Chudnovskiy, Gabriel D. Victora
Publikováno v:
Nature. 553:496-500
Interactions between different cell types are essential for multiple biological processes, including immunity, embryonic development and neuronal signalling. Although the dynamics of cell-cell interactions can be monitored in vivo by intravital micro
Autor:
Miriam Merad, J D Mocco, Christopher Faries, Johan Björkegren, Romain Remark, Ahmed J. Awad, El-ad David Amir, Letizia Amadori, Seunghee Kim-Schulze, Zichen Wang, Jennifer Li, Roza Shamailova, Christian Pina, Dawn M. Fernandez, Christopher Hill, Nicolas F. Fernandez, Avi Ma'ayan, Peter L. Faries, Chiara Giannarelli, Aleksey Chudnovskiy, Sacha Gnjatic, Nayaab S Khan, Christine K. Wong, Noah Moss, Adeeb Rahman
SUMMARYAtherosclerosis is driven by multifaceted contributions of the immune system within the circulation and at vascular focal sites. Yet the specific immune dysregulations within the atherosclerotic lesions that lead to clinical cerebro- and cardi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2586e5b26f6e770021ff5bcee033ccf
https://doi.org/10.1101/721688
https://doi.org/10.1101/721688
Autor:
Barbara, Maier, Andrew M, Leader, Steven T, Chen, Navpreet, Tung, Christie, Chang, Jessica, LeBerichel, Aleksey, Chudnovskiy, Shrisha, Maskey, Laura, Walker, John P, Finnigan, Margaret E, Kirkling, Boris, Reizis, Sourav, Ghosh, Natalie Roy, D'Amore, Nina, Bhardwaj, Carla V, Rothlin, Andrea, Wolf, Raja, Flores, Thomas, Marron, Adeeb H, Rahman, Ephraim, Kenigsberg, Brian D, Brown, Miriam, Merad
Publikováno v:
Nature. 580(7802)
Checkpoint blockade therapies have improved cancer treatment, but such immunotherapy regimens fail in a large subset of patients. Conventional type 1 dendritic cells (DC1s) control the response to checkpoint blockade in preclinical models and are ass