Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Aleksey A. Moskovtsev"'
Autor:
Sergey A. Menzikov, Danila M. Zaichenko, Aleksey A. Moskovtsev, Sergey G. Morozov, Aslan A. Kubatiev
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
γ-Aminobutyric acid type A receptors (GABAARs) are members of the pentameric ligand-gated ion channel (pLGIC) family, which are widespread throughout the invertebrate and vertebrate central nervous system. GABAARs are engaged in short-term changes o
Externí odkaz:
https://doaj.org/article/5d96546cf7854bf0a324020fdab33eb0
Autor:
Sergey A. Menzikov, Danila M. Zaichenko, Aleksey A. Moskovtsev, Sergey G. Morozov, Aslan A. Kubatiev
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 3, p 2764 (2023)
Zinc ions (Zn2+) are concentrated in various brain regions and can act as a neuromodulator, targeting a wide spectrum of postsynaptic receptors and enzymes. Zn2+ inhibits the GABAARs, and its potency is profoundly affected by the subunit composition
Externí odkaz:
https://doaj.org/article/a36f257ac69f4ce593f8899e4b2c0bdb
Autor:
Sergey A. Menzikov, Danila M. Zaichenko, Aleksey A. Moskovtsev, Sergey G. Morozov, Aslan A. Kubatiev
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 10, p 5320 (2022)
γ-Aminobutyric acid type A receptors (GABAARs) mediate primarily inhibitory synaptic transmission in the central nervous system. Following fast-paced activation, which provides the selective flow of mainly chloride (Cl−) and less bicarbonate (HCO3
Externí odkaz:
https://doaj.org/article/4b843e31bff24ab4aaaba73a9dda94b3
Autor:
Larisa V Smolyaninova, Alexandra A Shiyan, Leonid V Kapilevich, Alexander V Lopachev, Tatiana N Fedorova, Tatiana S Klementieva, Aleksey A Moskovtsev, Aslan A Kubatiev, Sergei N Orlov
Publikováno v:
PLoS ONE, Vol 14, Iss 9, p e0222767 (2019)
It was shown previously that inhibition of the ubiquitous α1 isoform of Na+,K+-ATPase by ouabain sharply affects gene expression profile via elevation of intracellular [Na+]i/[K+]i ratio. Unlike other cells, neurons are abundant in the α3 isoform o
Externí odkaz:
https://doaj.org/article/148a9b22d6e8453586b9fcbe49093f2e
Autor:
Aslan Amirkhanovich Kubatiev, Sergey G. Morozov, Danila M. Zaichenko, Aleksey A. Moskovtsev, Menzikov Sa
Publikováno v:
The FEBS Journal. 288:699-712
Neuronal intracellular chloride concentration ([Cl- ]i ) is a crucial determinant of transmission mediated by the γ-aminobutyric acid type A receptor (GABAA R), which subserves synaptic and extrasynaptic inhibition as well as excitation. The Cl- ion
Autor:
Kubatiev Aa, Aleksey A. Moskovtsev, Alisa A. Sokolovskaya, Ekaterina A. Korneeva, Dmitry V. Kolesov, E. D. Virus
Publikováno v:
Microgravity Science and Technology. 32:35-45
One cause of thrombocytopenia in astronauts after spaceflight is decreased platelet production. To increase our understanding of thrombopoiesis in humans while in space, we investigated the effects of simulated microgravity, achieved using a random p
Autor:
Ekaterina A. Korneeva, E. D. Virus, Danila M. Zaichenko, Dmitry V. Kolesov, Aslan Amirkhanovich Kubatiev, Alisa A. Sokolovskaya, Aleksey A. Moskovtsev
Publikováno v:
International Journal of Molecular Sciences
Volume 21
Issue 3
International Journal of Molecular Sciences, Vol 21, Iss 3, p 855 (2020)
Volume 21
Issue 3
International Journal of Molecular Sciences, Vol 21, Iss 3, p 855 (2020)
Experiments from flight- and ground-based model systems suggest that unexpected alterations of the human lymphoblastoid cell line Jurkat, as well as effects on cell growth, metabolism, and apoptosis, can occur in altered gravity conditions. Using a d
Autor:
Sergey A, Menzikov, Danila M, Zaichenko, Aleksey A, Moskovtsev, Sergey G, Morozov, Aslan A, Kubatiev
Publikováno v:
The FEBS journalReferences. 288(2)
Neuronal intracellular chloride concentration ([Cl
Autor:
Aleksey A. Moskovtsev, Danila M. Zaichenko, Sophie G. Malakho, Tatyana S. Klementyeva, Andrey A. Mironov, Ruslan A. Soldatov, Mikhail V. Mesitov, Aslan A. Kubatiev, Alisa A. Sokolovskaya
Publikováno v:
Scientific Reports
The accumulation of misfolded proteins in the endoplasmic reticulum (ER) lumen due to the disruption of the homeostatic system of the ER leads to the induction of the ER stress response. Cellular stress-induced pathways globally transform genes expre
Autor:
Tatiana N. Fedorova, Leonid V. Kapilevich, Sergei N. Orlov, Larisa V. Smolyaninova, Aleksey A. Moskovtsev, Tatiana S. Klementieva, A. V. Lopachev, A. A. Shiyan, Kubatiev Aa
Publikováno v:
PLoS ONE. 2019. Vol. 14, № 9. P. e0222767 (1-23)
PLoS ONE, Vol 14, Iss 9, p e0222767 (2019)
PLoS ONE
PLoS ONE, Vol 14, Iss 9, p e0222767 (2019)
PLoS ONE
It was shown previously that inhibition of the ubiquitous α1 isoform of Na+,K+-ATPase by ouabain sharply affects gene expression profile via elevation of intracellular [Na+]i/[K+]i ratio. Unlike other cells, neurons are abundant in the α3 isoform o