Conjugates of 3,5-Bis(arylidene)-4-piperidone and Sesquiterpene Lactones Have an Antitumor Effect via Resetting the Metabolic Phenotype of Cancer Cells.

Autor: Neganova ME; Institute of Physiologically Active Compounds at Federal Research Center of Problems of Chemical Physics and Medicinal Chemistry, Russian Academy of Sciences, 142432 Chernogolovka, Russia.; Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, 119991 Moscow, Russia., Aleksandrova YR; Institute of Physiologically Active Compounds at Federal Research Center of Problems of Chemical Physics and Medicinal Chemistry, Russian Academy of Sciences, 142432 Chernogolovka, Russia.; Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, 119991 Moscow, Russia., Sharova EV; Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, 119991 Moscow, Russia., Smirnova EV; Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, 119991 Moscow, Russia., Artyushin OI; Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, 119991 Moscow, Russia., Nikolaeva NS; Institute of Physiologically Active Compounds at Federal Research Center of Problems of Chemical Physics and Medicinal Chemistry, Russian Academy of Sciences, 142432 Chernogolovka, Russia., Semakov AV; Institute of Physiologically Active Compounds at Federal Research Center of Problems of Chemical Physics and Medicinal Chemistry, Russian Academy of Sciences, 142432 Chernogolovka, Russia., Schagina IA; Institute of Physiologically Active Compounds at Federal Research Center of Problems of Chemical Physics and Medicinal Chemistry, Russian Academy of Sciences, 142432 Chernogolovka, Russia., Akylbekov N; Laboratory of Engineering Profile 'Physical and Chemical Methods of Analysis', Korkyt Ata Kyzylorda University, Aiteke bi Str. 29A, 120014 Kyzylorda, Kazakhstan., Kurmanbayev R; Laboratory of Engineering Profile 'Physical and Chemical Methods of Analysis', Korkyt Ata Kyzylorda University, Aiteke bi Str. 29A, 120014 Kyzylorda, Kazakhstan., Orynbekov D; Laboratory of Engineering Profile 'Physical and Chemical Methods of Analysis', Korkyt Ata Kyzylorda University, Aiteke bi Str. 29A, 120014 Kyzylorda, Kazakhstan., Brel VK; Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, 119991 Moscow, Russia.

Publikováno v: Molecules (Basel, Switzerland) [Molecules] 2024 Jun 11; Vol. 29 (12). Date of Electronic Publication: 2024 Jun 11.

Perspectives of using microRNA-loaded nanocarriers for epigenetic reprogramming of drug resistant colorectal cancers.

Autor: Sukocheva OA; Cancer Center and Department of Radiation Oncology, The First Affiliated Hospital of Zhengzhou University, 1 Jianshedong Str., Zhengzhou 450052, China; The National Centre for Neuroimmunology and Emerging Diseases, Menzies Health Institute, Griffith University, Queensland, Australia; Discipline of Health Sciences, College of Nursing and Health Sciences, Flinders University, Bedford Park, SA 5042, Australia. Electronic address: olga.sukocheva@flinders.edu.au., Liu J; Cancer Center and Department of Radiation Oncology, The First Affiliated Hospital of Zhengzhou University, 1 Jianshedong Str., Zhengzhou 450052, China., Neganova ME; Institute of Physiologically Active Compounds of the Russian Academy of Sciences, 1, Severnii pr., Chernogolovka 142432, Russia., Beeraka NM; Cancer Center and Department of Radiation Oncology, The First Affiliated Hospital of Zhengzhou University, 1 Jianshedong Str., Zhengzhou 450052, China; Department of Human Anatomy, I.M. Sechenov First Moscow State Medical University (Sechenov University), 8/2 Trubetskaya Street, Moscow 119991, Russia; Center of Excellence in Molecular Biology and Regenerative Medicine (CEMR), Department of Biochemistry, JSS Academy of Higher Education and Research (JSS AHER), JSS Medical College, Mysuru, Karnataka, India., Aleksandrova YR; Institute of Physiologically Active Compounds of the Russian Academy of Sciences, 1, Severnii pr., Chernogolovka 142432, Russia., Manogaran P; Translational Research Laboratory, Department of Biotechnology, Bharathiar University, Coimbatore, Tamil Nadu 641046, India., Grigorevskikh EM; Department of Human Anatomy, I.M. Sechenov First Moscow State Medical University (Sechenov University), 8/2 Trubetskaya Street, Moscow 119991, Russia., Chubarev VN; Department of Human Anatomy, I.M. Sechenov First Moscow State Medical University (Sechenov University), 8/2 Trubetskaya Street, Moscow 119991, Russia., Fan R; Cancer Center and Department of Radiation Oncology, The First Affiliated Hospital of Zhengzhou University, 1 Jianshedong Str., Zhengzhou 450052, China. Electronic address: fccfanrt@zzu.edu.cn.

Publikováno v: Seminars in cancer biology [Semin Cancer Biol] 2022 Nov; Vol. 86 (Pt 2), pp. 358-375. Date of Electronic Publication: 2022 May 24.

Synthesis and biological testing of 3,5-bis(arylidene)-4-piperidone conjugates with 2,5-dihydro-5H-1,2-oxaphospholenes.

Autor: Neganova ME; Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, Moscow 119991, Russia; Institute of Physiologically Active Compounds, Russian Academy of Sciences, Chernogolovka 142432, Russia., Aleksandrova YR; Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, Moscow 119991, Russia; Institute of Physiologically Active Compounds, Russian Academy of Sciences, Chernogolovka 142432, Russia., Nikolaeva NS; Institute of Physiologically Active Compounds, Russian Academy of Sciences, Chernogolovka 142432, Russia., Brel VK; Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, Moscow 119991, Russia. Electronic address: v_brel@mail.ru.

Publikováno v: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2022 Oct 15; Vol. 74, pp. 128940. Date of Electronic Publication: 2022 Aug 12.

The Role of a Pathological Interaction between β-amyloid and Mitochondria in the Occurrence and Development of Alzheimer's Disease.

Autor: Nikolaeva NS; Federal State Budgetary Institution of Science Institute of Physiologically Active Compounds of the Russian Academy of Sciences, Chernogolovka, 142432 Russia., Yandulova EY; Federal State Budgetary Institution of Science Institute of Physiologically Active Compounds of the Russian Academy of Sciences, Chernogolovka, 142432 Russia., Aleksandrova YR; Federal State Budgetary Institution of Science Institute of Physiologically Active Compounds of the Russian Academy of Sciences, Chernogolovka, 142432 Russia., Starikov AS; Federal State Budgetary Institution of Science Institute of Physiologically Active Compounds of the Russian Academy of Sciences, Chernogolovka, 142432 Russia., Neganova ME; Federal State Budgetary Institution of Science Institute of Physiologically Active Compounds of the Russian Academy of Sciences, Chernogolovka, 142432 Russia.

Publikováno v: Acta naturae [Acta Naturae] 2022 Jul-Sep; Vol. 14 (3), pp. 19-34.

The Hydroxamic Acids as Potential Anticancer and Neuroprotective Agents.

Autor: Neganova ME; Institute of Physiologically Active Compounds of Russian Academy of Sciences, Chernogolovka, Russian Federation., Klochkov SG; Institute of Physiologically Active Compounds of Russian Academy of Sciences, Chernogolovka, Russian Federation., Aleksandrova YR; Institute of Physiologically Active Compounds of Russian Academy of Sciences, Chernogolovka, Russian Federation., Aliev G; Institute of Physiologically Active Compounds of Russian Academy of Sciences, Chernogolovka, Russian Federation.

Publikováno v: Current medicinal chemistry [Curr Med Chem] 2021; Vol. 28 (39), pp. 8139-8162.