Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Aleksandra Z. Kijac"'
Autor:
Chad M. Rienstra, Klaus Schulten, Stephen G. Sligar, Andrew J. Nieuwkoop, Amy Y. Shih, Aleksandra Z. Kijac
Publikováno v:
Biochemistry. 49:9190-9198
Nanodiscs are examples of discoidal nanoscale lipid-protein particles that have been extremely useful for the biochemical and biophysical characterization of membrane proteins. They are discoidal lipid bilayer fragments encircled and stabilized by tw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88cb31bcc9a901f24d47eb178829a753
https://doi.org/10.1021/bi1013722
https://doi.org/10.1021/bi1013722
Autor:
Rebecca L. Davis-Harrison, Stephen G. Sligar, Emad Tajkhorshid, James H. Morrissey, Chad M. Rienstra, Aleksandra Z. Kijac, Vincent S. Pureza, Y. Z. Ohkubo
Publikováno v:
Journal of Thrombosis and Haemostasis. 7:169-172
The clotting cascade requires the assembly of protease-cofactor complexes on membranes with exposed anionic phospholipids. Despite their importance, protein-membrane interactions in clotting remain relatively poorly understood. Calcium ions are known
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5618df497720100960d542a1e65912dd
https://doi.org/10.1111/j.1538-7836.2009.03390.x
https://doi.org/10.1111/j.1538-7836.2009.03390.x
Publikováno v:
Biochemistry. 46:13696-13703
Cytochrome P450 (CYP) 3A4 contributes to the metabolism of approximately 50% of commercial drugs by oxidizing a large number of structurally diverse substrates. Like other endoplasmic reticulum-localized P450s, CYP3A4 contains a membrane-anchoring N-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fd94bdd6477abbc7b6a12880686d375
https://doi.org/10.1021/bi701411g
https://doi.org/10.1021/bi701411g
Publikováno v:
Biophysical Journal. 91:3819-3828
Nanodiscs are an example of discoidal nanoscale self-assembled lipid/protein particles similar to nascent high-density lipoproteins, which reduce the risk of coronary artery disease. The major protein component of high-density lipoproteins is human a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf623386d7f094e21c28c573a91fe7eb
https://doi.org/10.1529/biophysj.106.087072
https://doi.org/10.1529/biophysj.106.087072