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pro vyhledávání: '"Aleksandra V. Sagaidak"'
Autor:
Tatyana A. Grigoreva, Aleksandra V. Sagaidak, Svetlana V. Vorona, Daria S. Novikova, Vyacheslav G. Tribulovich
Publikováno v:
ACS medicinal chemistry letters. 13(12)
Since the problem of transporter-mediated multidrug resistance of tumor cells is becoming increasingly important in cancer therapy, it is necessary to modulate the activity of efflux transporters of the ABC family, among which P-glycoprotein is the b
Publikováno v:
European Journal of Pharmacology. 935:175327
ABC transporters play an essential role in the development of multidrug resistance and thus are of interest in the context of anticancer therapy. However, MDR1, BCRP and MRP1 are involved in a number of key processes that maintain the viability of th