Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Aleksandra Szewczyk"'
Autor:
Aleksandra Szewczyk, Marta Andres-Mach, Mirosław Zagaja, Agnieszka Kaczmarczyk-Ziemba, Maciej Maj, Joanna Szala-Rycaj
Publikováno v:
Current Issues in Molecular Biology, Vol 45, Iss 3, Pp 2561-2579 (2023)
The aim of the study was to assess the effect of long-term administration of natural prebiotics: Jerusalem artichoke (topinambur, TPB) and inulin (INU) as well as one of the most popular antidepressants, fluoxetine (FLU), on the proliferation of neur
Externí odkaz:
https://doaj.org/article/eb0c4ff1316b4431ba5d0e211d4ea4c9
Autor:
Aleksandra Szewczyk, Mirosław Zagaja, Jarosław Bryda, Urszula Kosikowska, Dagmara Stępień-Pyśniak, Stanisław Winiarczyk, Marta Andres-Mach
Publikováno v:
Annals of Agricultural and Environmental Medicine, Vol 26, Iss 1, Pp 24-28 (2019)
Jerusalem artichoke ( Helianthus tuberosus Linne ) is a tuberous perennial plant of the Asteraceae family, which originates from North America, and is also known as wild sunflower or topinambur (TPB). It is characterized by good tolerance to frost, d
Externí odkaz:
https://doaj.org/article/fa237f9d24a84e0b94e4846f198db014
Autor:
Marcin Jakubiec, Michał Abram, Mirosław Zagaja, Marta Andres-Mach, Aleksandra Szewczyk, Gniewomir Latacz, Bartłomiej Szulczyk, Katarzyna Socała, Dorota Nieoczym, Piotr Wlaź, Cameron S. Metcalf, Karen Wilcox, Rafał M. Kamiński, Krzysztof Kamiński
Publikováno v:
Cells, Vol 11, Iss 12, p 1862 (2022)
In the present study, a focused combinatorial chemistry approach was applied to merge structural fragments of well-known TRPV1 antagonists with a potent anticonvulsant lead compound, KA-104, that was previously discovered by our group. Consequently,
Externí odkaz:
https://doaj.org/article/9d34a801f4aa4feab4747cefcea04a31
Publikováno v:
Brain Sciences, Vol 11, Iss 8, p 1014 (2021)
Seizures in about 40% of patients with epilepsy fail to respond to anti-seizure medication (ASM) and may lead to uncontrolled and prolonged seizures often inducing status epilepticus (SE). The aim of the study was to evaluate the impact of a long-ter
Externí odkaz:
https://doaj.org/article/eb5992c3a1a14ef0883fb675f713ce29
Autor:
Mirosław Zagaja, Aleksandra Szewczyk, Joanna Szala-Rycaj, Grzegorz Raszewski, Magdalena Chrościńska-Krawczyk, Michał Abram, Krzysztof Kamiński, Marta Andres-Mach
Publikováno v:
Molecules, Vol 26, Iss 11, p 3144 (2021)
C-11 is a hybrid compound derived from 2-(2,5-dioxopyrrolidin-1-yl) propanamide, with a wide spectrum of anticonvulsant activity and low neurotoxicity. The aim of this study was to determine the effects of C-11 on the protective action of various ant
Externí odkaz:
https://doaj.org/article/7263b3552423414a95fe678f303e9991
Publikováno v:
Annals of Agricultural and Environmental Medicine. 29:326-335
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c5cb554622fbcca5882826341199fe6
https://doi.org/10.26444/aaem/153448
https://doi.org/10.26444/aaem/153448
Autor:
Marta Andres-Mach, Mirosław Zagaja, Joanna Szala-Rycaj, Aleksandra Szewczyk, Michał Abram, Marcin Jakubiec, Katarzyna Ciepiela, Katarzyna Socała, Piotr Wlaź, Gniewomir Latacz, Nadia Khan, Krzysztof Kaminski
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 9; Pages: 8302
Epilepsy is a neurological disorder involving a number of disease syndromes with a complex etiology. A properly matched antiseizure drug (ASD) gives remission in up to 70% of patients. Nevertheless, there is still a group of about 30% of patients suf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53decfdbfce8268877ef7c4ee75db115
https://ruj.uj.edu.pl/xmlui/handle/item/311230
https://ruj.uj.edu.pl/xmlui/handle/item/311230
Autor:
Mirosław Zagaja, Anna Zagaja, Joanna Szala-Rycaj, Aleksandra Szewczyk, Marta Kinga Lemieszek, Grzegorz Raszewski, Marta Andres-Mach
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 7; Pages: 3492
Umbelliferone (7-hydroxycoumarin; UMB) is a coumarin with many biological properties, including antiepileptic activity. This study evaluated the effect of UMB on the ability of classical and novel antiepileptic drugs (e.g., lacosamide (LCM), levetira
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0767ac2b15377138e614f2c8f7a80fbe
Autor:
Krzysztof Kamiński, Marcin Jakubiec, Michał Abram, Mirosław Zagaja, Marta Andres-Mach, Aleksandra Szewczyk, Gniewomir Latacz, Bartłomiej Szulczyk, Katarzyna Socała, Dorota Nieoczym, Piotr Wlaź
Publikováno v:
Proceedings of 7th International Electronic Conference on Medicinal Chemistry.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5424577ee999906c6d4f860bf3c60e46
https://doi.org/10.3390/ecmc2021-11463
https://doi.org/10.3390/ecmc2021-11463
Autor:
Piotr Wlaź, Kinga Gawel, Camila V. Esguerra, Katarzyna Socała, Michał Abram, Dorota Nieoczym, Mirosław Zagaja, Bartłomiej Szulczyk, Gniewomir Latacz, Krzysztof Kamiński, Jarogniew J. Łuszczki, Aleksandra Szewczyk, Annamaria Lubelska, Mateusz Pieróg, Marta Andres-Mach, Marcin Jakubiec, Anna Rapacz
Publikováno v:
Neurotherapeutics
In our recent studies, we identified compound N-benzyl-2-(2,5-dioxopyrrolidin-1-yl)propanamide (AS-1) as a broad-spectrum hybrid anticonvulsant which showed potent protection across the most important animal acute seizure models such as the maximal e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::584bbd144a62a0d724635d308a7a724e
http://europepmc.org/articles/PMC7007424
http://europepmc.org/articles/PMC7007424