Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Aleksandra Sokolowska-Wedzina"'
Autor:
Marta Poźniak, Natalia Porębska, Mateusz Adam Krzyścik, Aleksandra Sokołowska-Wędzina, Kamil Jastrzębski, Martyna Sochacka, Jakub Szymczyk, Małgorzata Zakrzewska, Jacek Otlewski, Łukasz Opaliński
Publikováno v:
Molecular Medicine, Vol 27, Iss 1, Pp 1-13 (2021)
Abstract Background Antibody drug conjugates (ADCs) represent one of the most promising approaches in the current immuno-oncology research. The precise delivery of cytotoxic drugs to the cancer cells using ADCs specific for tumor-associated antigens
Externí odkaz:
https://doaj.org/article/9140866be0fd45268595cc52c24c3f7b
Autor:
Łukasz Opaliński, Aleksandra Sokołowska-Wędzina, Martyna Szczepara, Małgorzata Zakrzewska, Jacek Otlewski
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract Fibroblast growth factors (FGFs) and their plasma membrane-localized receptors (FGFRs) play a key role in the regulation of developmental processes and metabolism. Aberrant FGFR signaling is associated with the progression of serious metabol
Externí odkaz:
https://doaj.org/article/d0a42b98f3c44e8faef0eb26810fe047
Autor:
Marta Pozniak, Aleksandra Sokolowska‐Wedzina, Kamil Jastrzebski, Jakub Szymczyk, Natalia Porebska, Mateusz Adam Krzyscik, Malgorzata Zakrzewska, Marta Miaczynska, Jacek Otlewski, Lukasz Opalinski
Publikováno v:
Molecular Oncology, Vol 14, Iss 9, Pp 1998-2021 (2020)
Fibroblast growth factor receptor 1 (FGFR1) transmits signals through the plasma membrane regulating essential cellular processes like division, motility, metabolism, and death. Overexpression of FGFR1 is observed in numerous tumors and thus constitu
Externí odkaz:
https://doaj.org/article/41add822f32c4099b544103cf1062b2c
Autor:
Mateusz Adam Krzyscik, Malgorzata Zakrzewska, Vigdis Sørensen, Aleksandra Sokolowska-Wedzina, Michal Lobocki, Karolina Weronika Swiderska, Daniel Krowarsch, Antoni Wiedlocha, Jacek Otlewski
Publikováno v:
ACS Omega, Vol 2, Iss 7, Pp 3792-3805 (2017)
Externí odkaz:
https://doaj.org/article/187efb47319e4e688b8c5315fd2347c4
Publikováno v:
PLoS ONE, Vol 13, Iss 2, p e0192194 (2018)
Fibroblast growth factor receptors (FGFRs) are promising targets for antibody-based cancer therapies, as their substantial overexpression has been found in various tumor cells. Aberrant activation of FGF receptor 2 (FGFR2) signaling through overexpre
Externí odkaz:
https://doaj.org/article/d73d37e30b2446d88396c627277803c3
Autor:
Jacek Otlewski, Malgorzata Zakrzewska, Aleksandra Borek, Julia Chudzian, Grzegorz Chodaczek, Aleksandra Sokolowska-Wedzina
Supplementary Materials and Methods - Description of affinity maturation procedure used in the study and of the preparation of scFvD2 diabody and scFvD2-Fc; Supplementary Figure S1 - Reactivity of scFv clones against Fc fragment; Supplementary Figure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a5886c73fdc612ef08d289909f7e515
https://doi.org/10.1158/1541-7786.22511946.v1
https://doi.org/10.1158/1541-7786.22511946.v1
Autor:
Jacek Otlewski, Malgorzata Zakrzewska, Aleksandra Borek, Julia Chudzian, Grzegorz Chodaczek, Aleksandra Sokolowska-Wedzina
Targeted delivery of anticancer drugs using antibodies specific for tumor-associated antigens represents one of the most important approaches in current immuno-oncology research. Fibroblast growth factor receptor 1 (FGFR1) has been demonstrated to be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f7fcc6f46d3dbe75b0bea3ff3f3e51b6
https://doi.org/10.1158/1541-7786.c.6540084.v1
https://doi.org/10.1158/1541-7786.c.6540084.v1
Autor:
Mateusz Adam Krzyścik, Marta Poźniak, Łukasz Opaliński, Natalia Porębska, Martyna Sochacka, Jakub Szymczyk, Kamil Jastrzębski, Aleksandra Sokolowska-Wedzina, Malgorzata Zakrzewska, Jacek Otlewski
Publikováno v:
Molecular Medicine
Molecular Medicine, Vol 27, Iss 1, Pp 1-13 (2021)
Molecular Medicine, Vol 27, Iss 1, Pp 1-13 (2021)
Background Antibody drug conjugates (ADCs) represent one of the most promising approaches in the current immuno-oncology research. The precise delivery of cytotoxic drugs to the cancer cells using ADCs specific for tumor-associated antigens enables s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dc7150349cfb8c1c6f8767d94635735
https://doi.org/10.1186/s10020-021-00306-2
https://doi.org/10.1186/s10020-021-00306-2
Autor:
Daria Nawrocka, Aleksandra Sokolowska-Wedzina, Karolina Jendryczko, Mateusz Adam Krzyscik, Natalia Porębska, Marta Pozniak, Malgorzata Zakrzewska, Lukasz Opalinski, Jacek Otlewski, Anna Szlachcic
Publikováno v:
Journal of Visualized Experiments.
Cancer is currently the second most common cause of death worldwide. The hallmark of cancer cells is the presence of specific marker proteins such as growth factor receptors on their surface. This feature enables development of highly selective thera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dc5a9e6cdae65d48d0fa9f5cab41080
https://doi.org/10.3791/61918
https://doi.org/10.3791/61918
Autor:
Malgorzata Zakrzewska, Lukasz Opalinski, Martyna Szczepara, Jacek Otlewski, Aleksandra Sokolowska-Wedzina
Publikováno v:
The International Journal of Biochemistry & Cell Biology. 89:193-198
Fibroblast growth factors (FGFs) and their plasma membrane-localized receptors (FGFRs) transduce signals that regulate developmental processes and metabolism. In numerous cancer types genetic aberrations of FGFR1 lead to its uncontrolled activation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1b38282ed65a366e875a8a42556774c
https://doi.org/10.1016/j.biocel.2017.06.015
https://doi.org/10.1016/j.biocel.2017.06.015