Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Aleksandra Rusin"'
Autor:
Ellen Phillips, Naseer Ahmad, Li Sun, James Iben, Christopher J Walkey, Aleksandra Rusin, Tony Yuen, Clifford J Rosen, Ian M Willis, Mone Zaidi, Deborah L Johnson
Publikováno v:
eLife, Vol 11 (2022)
MAF1, a key repressor of RNA polymerase (pol) III-mediated transcription, has been shown to promote mesoderm formation in vitro. Here, we show that MAF1 plays a critical role in regulating osteoblast differentiation and bone mass. Global deletion of
Externí odkaz:
https://doaj.org/article/21c7d77c7c1c4131ace5a7b64a9a61c7
Autor:
Joanna Jazowiecka-Rakus, Aleksander Sochanik, Aleksandra Rusin, Agata Hadryś, Wojciech Fidyk, Nancy Villa, Masmudur M. Rahman, Ewa Chmielik, Lina S. Franco, Grant McFadden
Publikováno v:
Molecular Therapy: Oncolytics, Vol 18, Iss , Pp 335-350 (2020)
Oncolytic viruses can target neoplasms, triggering oncolytic and immune effects. Their delivery to melanoma lesions remains challenging. Bone-marrow-derived mesenchymal stem cells (MSCs) were shown to be permissive for oncolytic myxoma virus (MYXV),
Externí odkaz:
https://doaj.org/article/973a4d0f85a740e7b0773c2c8df8449e
Publikováno v:
Molecules, Vol 19, Iss 11, Pp 18558-18573 (2014)
The need to find new EGFR inhibitors for use in combination with radiotherapy in the treatment of solid tumors has drawn our attention to compounds derived from genistein, a natural isoflavonoid. The antiproliferative potential of synthetic genistein
Externí odkaz:
https://doaj.org/article/683a05289a7d4fc8af81e479a8129083
Autor:
Wieslaw Szeja, Grzegorz Grynkiewicz, Tadeusz Bieg, Piotr Swierk, Anna Byczek, Katarzyna Papaj, Radosław Kitel, Aleksandra Rusin
Publikováno v:
Molecules, Vol 19, Iss 6, Pp 7072-7093 (2014)
A series of glycoconjugates, derivatives of genistein containing a C-glycosylated carbohydrate moiety, were synthesized and their anticancer activity was tested in vitro in the human cell lines HCT 116 and DU 145. The target compounds 15–17 were sy
Externí odkaz:
https://doaj.org/article/73c89522c53a4f90a9b022dac9b5366f
Publikováno v:
Journal of Chemistry, Vol 2013 (2013)
This paper presents our attempt to investigate scopes and the limitations of olefin cross-metathesis (CM) reaction in the synthesis of complex C-glycosides of genistein and evaluation of their antiproliferative activities. Novel genistein glycoconjug
Externí odkaz:
https://doaj.org/article/dec71accff0c499a8ad44309a757c1a7
Autor:
Aleksandra Rusin, Maria E. Ruiz Echartea, Darlene G. Skapura, Karen Berman deRuiz, Christel M. Davis, Eric A. Ehli, Sandra L. Grimm, Christian Coarfa, Salma Kaochar
Publikováno v:
Cancer Research. 83:2580-2580
Background: Uveal melanoma (UM) originates from melanocytes residing in the uveal tract of an eye. Despite effective local control, approximately half of patients develop metastatic disease resistant to systemic chemotherapy and presenting poor respo
Autor:
Dallin Lowder, Jin Na Shin, Maria E. Ruiz-Echartea, Darlene Skapura, Jenny Deng, Aleksandra Rusin, Christel Davis, Erik Ehli, Cristian Coarfa, Michael Ittmann, Salma Kaochar
Publikováno v:
Cancer Research. 83:442-442
Background: Prostate cancer (PC) is the single most common and second most lethal cancer in men. Despite therapeutic advances in androgen receptor (AR)-targeting agents, progression to lethal, drug-resistant, castration-resistant prostate cancer (CRP
Autor:
Ellen Phillips, Naseer Ahmad, Li Sun, James Iben, Christopher J Walkey, Aleksandra Rusin, Tony Yuen, Clifford J Rosen, Ian M Willis, Mone Zaidi, Deborah L Johnson
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2065e638fec5eabe3da6ed0846310839
https://doi.org/10.7554/elife.74740.sa2
https://doi.org/10.7554/elife.74740.sa2
Publikováno v:
J Biol Chem
MAF1 homolog, negative regulator of RNA polymerase III (MAF1) is a key repressor of RNA polymerase (pol) III-dependent transcription and functions as a tumor suppressor. Its expression is frequently down-regulated in primary human hepatocellular carc
Autor:
Ellen Busschers, Christopher J. Walkey, Deborah L. Johnson, Naseer Ahmad, Clifford J. Rosen, Aleksandra Rusin, Li Sun, Mone Zaidi, James R. Iben, Tony Yuen, Ian M. Willis
Maf1, a key repressor of RNA polymerase III-mediated transcription, has been shown to promote mesoderm formation in vitro. Here, we show, for the first time, that Maf1 plays a critical role in the regulation of osteoblast differentiation and bone mas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d9fc538deec94750db36785f06adc10
https://doi.org/10.1101/2021.11.09.467887
https://doi.org/10.1101/2021.11.09.467887