Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Aleksandra Romaniuk-Drapala"'
Autor:
Aleksandra Romaniuk-Drapala, Paulina Skupin-Mrugalska, Olga Garbuzenko, Arash Hatefi, Tamara Minko
Publikováno v:
Cancer Cell International, Vol 24, Iss 1, Pp 1-14 (2024)
Abstract Background Olaparib is a PARP inhibitor inducing synthetic lethality in tumors with deficient homologous recombination (HRD) caused by BRCA1/2 mutations. The FDA has approved monotherapy for first-line platinum-sensitive, recurrent high-grad
Externí odkaz:
https://doaj.org/article/2350485a9cd741f996cbc87a97309a02
Autor:
Aleksandra Romaniuk-Drapała, Ewa Totoń, Magdalena Taube, Malgorzata Idzik, Błażej Rubiś, Natalia Lisiak
Publikováno v:
Cancers, Vol 16, Iss 13, p 2481 (2024)
Breast cancer is one of the most frequently detected malignancies worldwide. It is responsible for more than 15% of all death cases caused by cancer in women. Breast cancer is a heterogeneous disease representing various histological types, molecular
Externí odkaz:
https://doaj.org/article/f1a00e76e5b349ac8c777d74bf7c6687
Autor:
Anna Budzianowska, Ewa Totoń, Aleksandra Romaniuk-Drapała, Małgorzata Kikowska, Jaromir Budzianowski
Publikováno v:
Life, Vol 13, Iss 2, p 556 (2023)
The aim of the study is to investigate whether the bioactive compounds isolated from P. lanceolata inflorescences, namely, phenylethanoid glucosides, acteoside, plantamajoside, and a flavonoid, isorhamnetin-3-O-rutinoside-4′-O-glucoside, possessed
Externí odkaz:
https://doaj.org/article/46cb6ea970ec49f68786f7f3f8ccc6a6
Autor:
Aleksandra Romaniuk-Drapała, Ewa Totoń, Natalia Konieczna, Marta Machnik, Wojciech Barczak, Dagmar Kowal, Przemysław Kopczyński, Mariusz Kaczmarek, Błażej Rubiś
Publikováno v:
Cells, Vol 10, Iss 4, p 867 (2021)
Telomerase is known to contribute to telomere maintenance and to provide cancer cell immortality. However, numerous reports are showing that the function of the enzyme goes far beyond chromosome ends. The study aimed to explore how telomerase downreg
Externí odkaz:
https://doaj.org/article/94b2ff0fa8964e498f8444fa1f7a88f3
Autor:
Magdalena Paczkowska, Justyna Chanaj-Kaczmarek, Aleksandra Romaniuk-Drapała, Błażej Rubiś, Daria Szymanowska, Joanna Kobus-Cisowska, Emilia Szymańska, Katarzyna Winnicka, Judyta Cielecka-Piontek
Publikováno v:
Journal of Clinical Medicine, Vol 9, Iss 4, p 1208 (2020)
Chelidonium majus (also known as celandine) contains pharmacologically active compounds such as isoquinoline alkaloids (e.g., chelidonine, sanguinarine), flavonoids, saponins, carotenoids, and organic acids. Due to the presence of isoquinoline alkalo
Externí odkaz:
https://doaj.org/article/9eec4ad1768b4116b240bf39ec84407c
Telomerase Inhibitor TMPyP4 Alters Adhesion and Migration of Breast-Cancer Cells MCF7 and MDA-MB-231
Autor:
Natalia Konieczna, Aleksandra Romaniuk-Drapała, Natalia Lisiak, Ewa Totoń, Anna Paszel-Jaworska, Mariusz Kaczmarek, Błażej Rubiś
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 11, p 2670 (2019)
Human telomeres were one of the first discovered and characterized sequences forming quadruplex structures. Association of these structures with oncogenic and tumor suppressor proteins suggests their important role in cancer development and therapy e
Externí odkaz:
https://doaj.org/article/ef32499debb4454db1c3699161cc58db