Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Aleksandra Redzicka"'
Autor:
Jakub Mikus, Piotr Świątek, Patrycja Przybyła, Edward Krzyżak, Aleksandra Marciniak, Aleksadra Kotynia, Aleksandra Redzicka, Benita Wiatrak, Paulina Jawień, Tomasz Gębarowski, Łukasz Szczukowski
Publikováno v:
Molecules, Vol 28, Iss 14, p 5479 (2023)
Secure and efficient treatment of diverse pain and inflammatory disorders is continually challenging. Although NSAIDs and other painkillers are well-known and commonly available, they are sometimes insufficient and can cause dangerous adverse effects
Externí odkaz:
https://doaj.org/article/9678f42607a34b699dd94b8ddca70f65
Autor:
Aleksandra Redzicka, Benita Wiatrak, Izabela Jęśkowiak-Kossakowska, Andrzej Kochel, Remigiusz Płaczek, Żaneta Czyżnikowska
Publikováno v:
Pharmaceuticals, Vol 16, Iss 6, p 804 (2023)
In the present study, we characterize the biological activity of a newly designed and synthesized series of 15 compounds 2-[2-hydroxy-3-(4-substituted-1-piperazinyl)propyl] derivatives of pyrrolo[3,4-c]pyrrole 3a–3o. The compounds were obtained wit
Externí odkaz:
https://doaj.org/article/d27fdeddf76e4ac7b66d62e45bd5eacf
Autor:
Łukasz Szczukowski, Jadwiga Maniewska, Benita Wiatrak, Paulina Jawień, Edward Krzyżak, Aleksandra Kotynia, Aleksandra Marciniak, Maciej Janeczek, Aleksandra Redzicka
Publikováno v:
Membranes, Vol 13, Iss 3, p 349 (2023)
Despite the widespread and easy access to NSAIDs, effective and safe treatment of various inflammatory disorders is still a serious challenge because of the severe adverse effects distinctive to these drugs. The Mannich base derivatives of pyrrolo[3,
Externí odkaz:
https://doaj.org/article/ab4973f35a5a4adc8b930c8c69f3db4a
Autor:
Anna Wójcicka, Aleksandra Redzicka
Publikováno v:
Pharmaceuticals, Vol 14, Iss 4, p 354 (2021)
Pyrrolo[3,4-c]pyridine is one of the six structural isomers of the bicyclic ring system containing a pyrrole moiety fused to a pyridine nucleus. The broad spectrum of pharmacological properties of pyrrolo[3,4-c]pyridine derivatives is the main reason
Externí odkaz:
https://doaj.org/article/eb2ac6eadf414133ab46b4e9ec5b490a
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 3, p 1410 (2021)
In the present paper, we describe the biological activity of the newly designed and synthesized series N-substituted 3,4-pyrroledicarboximides 2a–2p. The compounds 2a–2p were obtained in good yields by one-pot, three-component condensation of pyr
Externí odkaz:
https://doaj.org/article/93022466ca00427aa512f759b3d6abb3
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 3
International Journal of Molecular Sciences, Vol 22, Iss 1410, p 1410 (2021)
Volume 22
Issue 3
International Journal of Molecular Sciences, Vol 22, Iss 1410, p 1410 (2021)
In the present paper, we describe the biological activity of the newly designed and synthesized series N-substituted 3,4-pyrroledicarboximides 2a–2p. The compounds 2a–2p were obtained in good yields by one-pot, three-component condensation of pyr
Autor:
Łukasz Szczukowski, Aleksandra Marciniak, Benita Wiatrak, Tomasz Gębarowski, Edward Krzyżak, Aleksandra Redzicka, Piotr Świątek, Katarzyna Gębczak
Publikováno v:
Bioorganic chemistry. 102
Novel Mannich base analogues of pyrrolo[3,4-d]pyridazinone 7a,b-13a,b are designed and synthesized as potential anti-inflammatory agents. The title compounds are obtained via convenient one-pot synthesis with good yields. Their structures and propert
Autor:
Aleksandra Redzicka, Anna Wójcicka
Publikováno v:
Pharmaceuticals, Vol 14, Iss 354, p 354 (2021)
Pharmaceuticals
Pharmaceuticals
Pyrrolo[3,4-c]pyridine is one of the six structural isomers of the bicyclic ring system containing a pyrrole moiety fused to a pyridine nucleus. The broad spectrum of pharmacological properties of pyrrolo[3,4-c]pyridine derivatives is the main reason
Autor:
Łukasz Szczukowski, Żaneta Czyżnikowska, Aleksandra Redzicka, Benita Wiatrak, Katarzyna Gębczak, Andrzej Kochel
Publikováno v:
Bioorganicmedicinal chemistry. 27(17)
In the present paper we describe the biological activity of newly designed and synthesized series of pyrrolo[3,4-c]pyrrole Mannich bases (7a-n). The Mannich bases were obtained in good yields by one-pot, three-component condensation of pyrrolo[3,4-c]
Publikováno v:
X-ray Structure Analysis Online. 34:55-56