Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Aleksandra Narczyk"'
Autor:
Aleksandra Narczyk, Sebastian Stecko
Publikováno v:
Organicbiomolecular chemistry. 18(30)
A method for the preparation of enantiopure β-tert-amino alcohols bearing a tetrasubstituted C-stereocenter, as well as their conversion into selected medicinally privileged heterocyclic systems (morpholines, aziridines, piperazines) is reported. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7bc1799031be837f74557fb1f89eeff
https://pubmed.ncbi.nlm.nih.gov/32700713
https://pubmed.ncbi.nlm.nih.gov/32700713
Publikováno v:
Organic & Biomolecular Chemistry. 17:2770-2775
Total synthesis of levetiracetam, an active ingredient of epilepsy treatment medications, is reported. The reported method is based on a one-pot dehydration/sigmatropic rearrangement of (R,E)-hept-4-en-3-ol carbamate to the corresponding allylamine d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edaf232fe927b65fdafb0e46239a1868
https://doi.org/10.1039/c9ob00111e
https://doi.org/10.1039/c9ob00111e
Autor:
Sebastian Stecko, Aleksandra Narczyk
Publikováno v:
Organicbiomolecular chemistry. 18(6)
The synthesis of α-aryl- and α-alkyl-substituted serine derivatives via [3,3]-sigmatropic rearrangement of allyl carbamates as a key step is reported. Allyl carbamates were obtained from the corresponding allyl alcohols. The former were prepared th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52ad8aa0a192c07998010b11149a5376
https://pubmed.ncbi.nlm.nih.gov/31995087
https://pubmed.ncbi.nlm.nih.gov/31995087
Publikováno v:
Organicbiomolecular chemistry. 16(21)
A synthesis of non-racemic β-alkyl-β-aryl allyl alcohols and their transformation into allylamines bearing a quaternary stereogenic center is reported. The allyl alcohols were prepared either by Cu-catalyzed enantioselective reduction of enones or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0c67a2d8755e05884dfbba03b6e8f8e
https://pubmed.ncbi.nlm.nih.gov/29745946
https://pubmed.ncbi.nlm.nih.gov/29745946