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pro vyhledávání: '"Aleksandra Levina"'
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
The essential protein kinase PDK1 is activated by phospoinositide-mediated dimerization and trans-autophosphorylation. Here, the authors show that in the absence of PIP3 or PI(3,4)P2 phosphoinositides, PDK1 is maintained in an inactive, autoinhibited
Externí odkaz:
https://doaj.org/article/12cf17b4eda64639a643128b30b79f8c
Publikováno v:
Nature communications. 13(1)
3-phosphoinositide-dependent kinase 1 (PDK1) is an essential serine/threonine protein kinase, which plays a crucial role in cell growth and proliferation. It is often referred to as a ‘master’ kinase due to its ability to activate at least 23 dow
3-phosphoinositide-dependent kinase 1 (PDK1) is an essential serine/threonine protein kinase, which plays a crucial role in cell growth and proliferation. It is often referred to as a ‘master’ kinase due to its ability to activate at least 23 dow
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::90ce55777545087c11f8b71513050011
https://doi.org/10.1101/2021.10.08.463254
https://doi.org/10.1101/2021.10.08.463254