Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Aleksandra J. Recupero"'
Autor:
Pierre De Rossi, Toshihiro Nomura, Robert J. Andrew, Nicolas Y. Masse, Vandana Sampathkumar, Timothy F. Musial, Ari Sudwarts, Aleksandra J. Recupero, Thomas Le Metayer, Mitchell T. Hansen, Ha-Na Shim, Sofia V. Krause, David J. Freedman, Vytas P. Bindokas, Narayanan Kasthuri, Daniel A. Nicholson, Anis Contractor, Gopal Thinakaran
Publikováno v:
Cell Reports, Vol 30, Iss 10, Pp 3520-3535.e7 (2020)
Summary: BIN1, a member of the BAR adaptor protein family, is a significant late-onset Alzheimer disease risk factor. Here, we investigate BIN1 function in the brain using conditional knockout (cKO) models. Loss of neuronal Bin1 expression results in
Externí odkaz:
https://doaj.org/article/3ee20aa26dbb4398a318c588047a8aa8
Autor:
Baptiste Libé-Philippot, Ryohei Iwata, Aleksandra J Recupero, Keimpe Wierda, Martyna Ditkowska, Vaiva Gaspariunaite, Ben Vermaercke, Eugénie Peze-Heidsieck, Daan Remans, Cécile Charrier, Franck Polleux, Pierre Vanderhaeghen
Human-specific (HS) genes are potential drivers of brain evolution, but their impact on human neuron development and disease remains unclear. Here we studied HS genes SRGAP2B/C in human cortical projection neurons (CPNs) in vivo, using xenotransplant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8f4042380d2740de6d744a095abdf249
https://doi.org/10.1101/2023.03.01.530630
https://doi.org/10.1101/2023.03.01.530630
Autor:
Robert J. Andrew, Haley R. Kowalski, Thomas Guerbette, Steven L. Wagner, Pierre De Rossi, Lisa Laury-Kleintop, Richard C. Rice, Aleksandra J. Recupero, Phuong Nguyen, Sofia V. Krause, Gopal Thinakaran
Publikováno v:
Journal of Biological Chemistry. 294:4477-4487
Alzheimer's disease (AD) is pathologically characterized by the deposition of the β-amyloid (Aβ) peptide in senile plaques in the brain, leading to neuronal dysfunction and eventual decline in cognitive function. Genome-wide association studies hav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ee884159a138dac385e3916b423d4aa
https://doi.org/10.1074/jbc.ra118.006379
https://doi.org/10.1074/jbc.ra118.006379
Autor:
Narayanan Kasthuri, Robert J. Andrew, Thomas Le Metayer, Vytas P. Bindokas, Ha Na Shim, Gopal Thinakaran, Sofia V. Krause, David J. Freedman, Mitchell T. Hansen, Vandana Sampathkumar, Daniel A. Nicholson, Ari Sudwarts, Anis Contractor, Nicolas Y. Masse, Timothy F. Musial, Toshihiro Nomura, Pierre De Rossi, Aleksandra J. Recupero
Publikováno v:
Cell reports
Cell Reports, Vol 30, Iss 10, Pp 3520-3535.e7 (2020)
Cell Reports, Vol 30, Iss 10, Pp 3520-3535.e7 (2020)
SUMMARY BIN1, a member of the BAR adaptor protein family, is a significant late-onset Alzheimer disease risk factor. Here, we investigate BIN1 function in the brain using conditional knockout (cKO) models. Loss of neuronal Bin1 expression results in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a7407a457ffe8338cd75b9c89496a8d
https://pubmed.ncbi.nlm.nih.gov/32160554
https://pubmed.ncbi.nlm.nih.gov/32160554
Autor:
Toshihiro Nomura, Sofia V. Krause, Vytas P. Bindokas, Mitchell T. Hansen, Narayanan Kasthuri, Vandana Sampathkumar, Nicolase Y. Masse, Robert J. Andrew, Pierre De Rossi, Timothy F. Musial, Anis Contractor, David J. Freedman, Ha-Na Shim, Aleksandra J. Recupero, Daniel A. Nicholson, Ari Sudwarts, Gopal Thinakaran, Thomas Le Metayer
Publikováno v:
SSRN Electronic Journal.
BIN1, a member of the BAR adaptor protein family, is a significant late-onset Alzheimer’s disease risk factor. Here, we investigated BIN1 function in the brain using conditional knockout (cKO) models. The loss of neuronal Bin1 expression resulted i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::35d57d7b1b52e57f755d84e09fa8fcd2
https://doi.org/10.2139/ssrn.3443599
https://doi.org/10.2139/ssrn.3443599