Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Aleksandra J. Ozga"'
Publikováno v:
Cell Reports, Vol 31, Iss 8, Pp - (2020)
Summary: Generating robust CD4+ T-helper cell type 1 (Th1) responses is essential for protective vaccine-induced type 1 immunity. Here, we examine whether immunization formulation associated with enhanced vaccine efficacy promotes antigen targeting a
Externí odkaz:
https://doaj.org/article/9420a957baf34ddb9e5d4ea8ab298466
Publikováno v:
Immunity
Chemokines are chemotactic cytokines that regulate the migration of immune cells. Chemokines function as cues for the coordinated recruitment of immune cells into and out of tissue and also guide the spatial organization and cellular interactions of
Publikováno v:
Cell Reports, Vol 31, Iss 8, Pp-(2020)
Cell reports
Cell reports
SUMMARY Generating robust CD4+ T-helper cell type 1 (Th1) responses is essential for protective vaccine-induced type 1 immunity. Here, we examine whether immunization formulation associated with enhanced vaccine efficacy promotes antigen targeting an
Autor:
Thorsten R. Mempel, Philippe Dehio, Andrew D. Luster, Aleksandra J. Ozga, Rachel L. Servis, Mateus E. Lopes, Mauro Di Pilato, Jeffrey Lian, Melvyn T. Chow
Publikováno v:
Immunity
CD8(+) T cells responding to chronic infection adapt an altered differentiation program that provides some restrain on pathogen replication yet limits immunopathology. This adaptation is imprinted in stem-like cells and propagated to their progeny. U
Autor:
Shannon N. Geels, Michela Corsini, Martin Thelen, Vinidhra Mani, Esteban Carrizosa, Aleksandra J. Ozga, Jasper N. Prüßmann, Shivashankar Othy, Ademi Zhakyp, Francesco Marangoni, Thorsten R. Mempel, Ross D. Warner, Mauro Di Pilato
Publikováno v:
Cell, vol 184, iss 15
Foxp3+ T regulatory (Treg) cells promote immunological tumor tolerance, but how their immune-suppressive function is regulated in the tumor microenvironment (TME) remains unknown. Here, we used intravital microscopy to characterize the cellular inter
Autor:
Aleksandra J. Ozga, Jens V. Stein, Beatrice Bolinger, Virginie Galati-Fournier, Ed Palmer, Simone Keck, Angela J.T. Bosch, Ondrej Stepanek
Publikováno v:
Cell. Immunol.
While autoimmune T cells are present in most individuals, only a minority of the population suffers from an autoimmune disease. To better appreciate the limits of T cell tolerance, we carried out experiments to determine how many autoimmune T cells a
Autor:
Jennifer A. Lo, Melvyn T. Chow, Aleksandra J. Ozga, Genevieve M. Boland, Dennie T. Frederick, David E. Fisher, Andrew D. Luster, Gordon J. Freeman, Rachel L. Servis
Publikováno v:
Immunity
Summary Despite compelling rates of durable clinical responses to programmed cell death-1 (PD-1) blockade, advances are needed to extend these benefits to resistant tumors. We found that tumor-bearing mice deficient in the chemokine receptor CXCR3 re
Publikováno v:
Journal of immunological methods
Recercat. Dipósit de la Recerca de Catalunya
instname
Recercat. Dipósit de la Recerca de Catalunya
instname
Reactive lymph nodes (LNs) are sites where pMHC-loaded dendritic cells (DCs) interact with rare cognate T cells, leading to their clonal expansion. While DC interactions with T cell subsets critically shape the ensuing immune response, surprisingly l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95f75fd851d1a2f2c8a57fe783b1c889
http://hdl.handle.net/10230/27845
http://hdl.handle.net/10230/27845
Publikováno v:
Computational and mathematical methods in medicine
Computational and Mathematical Methods in Medicine
Recercat. Dipósit de la Recerca de Catalunya
instname
Computational and Mathematical Methods in Medicine, Vol 2012 (2012)
Computational and Mathematical Methods in Medicine
Recercat. Dipósit de la Recerca de Catalunya
instname
Computational and Mathematical Methods in Medicine, Vol 2012 (2012)
Deep tissue imaging has become state of the art in biology, but now the problem is to quantify spatial information in a global, organ-wide context. Although access to the raw data is no longer a limitation, the computational tools to extract biologic