Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Aleksandra Ivanová"'
Autor:
Jiří Řehulka, Michal Jurášek, Pavel Dráber, Aleksandra Ivanová, Soňa Gurská, Kateřina Ječmeňová, Olena Mokshyna, Marián Hajdúch, Pavel Polishchuk, Pavel B. Drašar, Petr Džubák
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 39, Iss 1 (2024)
Estradiol dimers (EDs) possess significant anticancer activity by targeting tubulin dynamics. In this study, we synthesised 12 EDs variants via copper-catalysed azide-alkyne cycloaddition (CuAAC) reaction, focusing on structural modifications within
Externí odkaz:
https://doaj.org/article/c6ffcd1be2c54765a90525facd8c6a33
Autor:
Michal, Jurášek, Jiří, Řehulka, Lenka, Hrubá, Aleksandra, Ivanová, Soňa, Gurská, Olena, Mokshyna, Pavel, Trousil, Lukáš, Huml, Pavel, Polishchuk, Marián, Hajdúch, Pavel B, Drašar, Petr, Džubák
Publikováno v:
Bioorganic Chemistry. 131:106334
Microtubule dynamic is exceptionally sensitive to modulation by small-molecule ligands. Our previous work presented the preparation of microtubule-targeting estradiol dimer (ED) with anticancer activity. In the present study, we explore the effect of
Publikováno v:
Journal of Cheminformatics, Vol 15, Iss 1, Pp 1-11 (2023)
Abstract Docking of large compound collections becomes an important procedure to discover new chemical entities. Screening of large sets of compounds may also occur in de novo design projects guided by molecular docking. To facilitate these processes
Externí odkaz:
https://doaj.org/article/3a7d632969544228a1e857f6137518e0
Autor:
Rumen Harizanov, Mihaela Videnova, Ognyan Mikov, Iskren Kaftandjiev, Aleksandra Ivanova, Eleonora Kaneva, Raina Borisova, Nina Tsvetkova, Iskra Rainova, Violeta Yakimova
Publikováno v:
Problems of Infectious and Parasitic Diseases, Vol 51, Iss 2 (2024)
INTRODUCTION: Infections caused by parasites still represent an important global health problem. Although parasitic infections are responsible for significant morbidity and mortality in developing countries, they are also prevalent in developed count
Externí odkaz:
https://doaj.org/article/cf0e3f0e84d94f7ea98f784b086d5673
Autor:
Ognyan Mikov, Sofia `Boneva-Bukovska, Nadya Ivanova-Aleksandrova, Milena Nikolova, Savina Stoitsova, Aleksandra Ivanova
Publikováno v:
Problems of Infectious and Parasitic Diseases, Vol 51, Iss 1 (2023)
Mosquitoes are a group of blood-sucking insects that plays a major role in disease transmission in both humans and animals. They can pose a heavy nuisance, or serve as vectors of numerous viruses and parasites on most continents, including Europe. Th
Externí odkaz:
https://doaj.org/article/740084c3be73450db92667df5c4a4685
Publikováno v:
Pharmacia, Vol 70, Iss 1, Pp 61-65 (2023)
Phlomis tuberosa L. (Lamiaceae) is a flowering perennial plant, native to Eurasia, and sparsely distributed in Bulgaria. The species has been proved to accumulate flavonoids, iridoids, phenolic glycosides, as well as essential oil. To now, there is n
Externí odkaz:
https://doaj.org/article/3358e00a961d42babbe6686954ff61c4
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 23, p 16927 (2023)
Pneumocystis jirovecii pneumonia (PCP) is a significant cause of morbidity and mortality in immunocompromised people. The widespread use of trimethoprim-sulfamethoxazole (TMP-SMZ) for the treatment and prophylaxis of opportunistic infections (includi
Externí odkaz:
https://doaj.org/article/7e6a8eda51de403885e8154e02d84f0e
Autor:
Rumen Harizanov, Iskra Rainova, Nina Tsvetkova, Iskren Kaftandjiev, Raina Borisova, Mihaela Videnova, Eleonora Kaneva, Ognyan Mikov, Aleksandra Ivanova, Violeta Yakimova
Publikováno v:
Problems of Infectious and Parasitic Diseases, Vol 50, Iss 2 (2023)
The aim of this report is to review and assess the dynamics of parasitic diseases in Bulgaria during 2020-2021. Materials and methods. The analysis is based on the annual reports of the Regional Health Inspectorates (RHIs) about the cases of regist
Externí odkaz:
https://doaj.org/article/9cd22da4a0524dc4a6876718be3014b9
Autor:
Eleonora Kaneva, Rumen Harizanov, Nina Tsvetkova, Iskren Kaftanjiev, Raina Borisova, Aleksandra Ivanova, Mihaela Videnova, Desislava Velcheva, Ivailo Alexiev, Reneta Dimitrova, Maria Pavlova, Ekaterina Aleksandrova
Publikováno v:
Problems of Infectious and Parasitic Diseases, Vol 50, Iss 2 (2023)
Enterobius vermicularis is an intestinal parasite with a cosmopolitan distribution and the disease which causes (enterobiasis) is one of the most common helminth infection worldwide. According to literature data it affects nearly 1 billion people and
Externí odkaz:
https://doaj.org/article/4d7d7559d3344844b25f90fe1ab8ec06
Autor:
Rumen Harizanov, Nina Tsvetkova, Aleksandra Ivanova, Raina Enikova, Mihaela Videnova, Iskra Rainova, Eleonora Kaneva, Iskren Kaftandjiev, Dimitar Strashimirov, Nina Yancheva-Petrova, Ivan Simeonovski, Viktoria Levterova, Nikolay Yanev
Publikováno v:
Biomedicines, Vol 11, Iss 7, p 1851 (2023)
Background: Pneumocystis pneumonia (PCP) commonly affects immunocompromised individuals, whereas in immunocompetent persons, it occurs relatively rarely, and in most cases, the Pneumocystis infection is detected as an asymptomatic colonization. The p
Externí odkaz:
https://doaj.org/article/fbf5010653a34d2e92088cf0d13e7d92