Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Aleksandra Dyś"'
Autor:
Anna Ronowska, Andrzej Szutowicz, Hanna Bielarczyk, Sylwia Gul-Hinc, Joanna Klimaszewska-Łata, Aleksandra Dyś, Marlena Zyśk, Agnieszka Jankowska-Kulawy
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 12 (2018)
Brain neurons, to support their neurotransmitter functions, require a several times higher supply of glucose than non-excitable cells. Pyruvate, the end product of glycolysis, through pyruvate dehydrogenase complex reaction, is a principal source of
Externí odkaz:
https://doaj.org/article/6ab28e4ada614c72940a51303627420d
Autor:
Aleksandra Dyś, Artur Lehmann, Anna Szczoczarz, Konrad Boblewski, Aleksandra Marchwińska, Barbara Lewko, Apolonia Rybczyńska
Publikováno v:
Pharmacological Reports. 71:478-484
Background The Ca2+ triggered insulin exocytosis in β cells of the pancreatic islets may be the result of Ca2+ influx through L-type voltage dependent calcium channels (VDCC) localized in the plasma membrane, as well as of liberation of Ca2+ from in
Autor:
Apolonia Rybczyńska, Artur Lehmann, Aleksandra Dyś, Aleksandra Marchwińska, Konrad Boblewski, Barbara Lewko
Publikováno v:
Pharmacological Reports. 69:709-713
Background The calcium-sensing receptor (CaR) has been found not only in parathyroid glands but also in other tissues, e.g. in β cells of the pancreatic islets. Therefore, CaR might likely mediate the mechanism of insulin secretion. The present stud
Autor:
Hanna Bielarczyk, S. Gul-Hinc, Anna Ronowska, Andrzej Szutowicz, Aleksandra Dyś, Joanna Klimaszewska-Łata, Marlena Zyśk, Agnieszka Jankowska-Kulawy
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 12 (2018)
Frontiers in Cellular Neuroscience
Frontiers in Cellular Neuroscience
Brain neurons, to support their neurotransmitter functions, require a several times higher supply of glucose than non-excitable cells. Pyruvate, the end product of glycolysis, through pyruvate dehydrogenase complex reaction, is a principal source of
Autor:
S. Gul-Hinc, Aleksandra Dyś, Marlena Zyśk, Anna Ronowska, Andrzej Szutowicz, Beata Gapys, Monika Sakowicz-Burkiewicz, Hanna Bielarczyk
Publikováno v:
Journal of Alzheimer's disease : JAD. 56(3)
Pyruvate dehydrogenase reaction utilizing glucose-derived pyruvate is an almost exclusive source of acetyl-CoA in different cell mitochondrial compartments of the brain. In neuronal mitochondria, the largest fraction of acetyl-CoA is utilized for ene
Autor:
Tadeusz Pawelczyk, Aleksandra Dyś, Andrzej Szutowicz, Marlena Zyśk, Hanna Bielarczyk, S. Gul-Hinc, Anna Ronowska, Joanna Klimaszewska-Łata
Publikováno v:
Biochemical Society Transactions. 42:1101-1106
Intramitochondrial decarboxylation of glucose-derived pyruvate by PDHC (pyruvate dehydrogenase complex) is a principal source of acetyl-CoA, for mitochondrial energy production and cytoplasmic synthetic pathways in all types of brain cells. The inhib
Autor:
S. Gul-Hinc, Aleksandra Dyś, Anna Ronowska, Marlena Zyśk, Hanna Bielarczyk, Joanna Klimaszewska-Łata, Andrzej Szutowicz
Publikováno v:
Neurochemical Research
There are several systemic and intracerebral pathologic conditions, which limit provision and utilization of energy precursor metabolites in neuronal cells. Energy deficits cause excessive depolarization of neuronal cells triggering glutamate-zinc ev
Autor:
Anna Ronowska, Andrzej Szutowicz, Joanna Klimaszewska-Łata, Piotr Romianowski, Agnieszka Jankowska-Kulawy, Aleksandra Dyś, Tadeusz Pawelczyk, Hanna Bielarczyk
Publikováno v:
Neurochemistry International. 56:143-151
Excessive accumulation of zinc in the brain is one of putative factors involved in pathomechanism of cholinergic encephalopathies. The aim of this work was to investigate whether short-term increase of zinc concentration in the extracellular space ma
Autor:
Agnieszka, Jankowska-Kulawy, Sylwia, Gul-Hinc, Hanna, Bielarczyk, Janusz B, Suszkiw, Tadeusz, Pawełczyk, Aleksandra, Dyś, Andrzej, Szutowicz
Publikováno v:
Acta neurobiologiae experimentalis. 68(4)
Age-dependent accumulation of lead in brain has been implicated in the pathomechanisms of Alzheimer's disease. The aim of this work was to investigate whether cholinotoxic effects of lead may result from alterations in acetyl-CoA metabolism. One day
Autor:
Aleksandra Dyś, S. Gul-Hinc, Hanna Bielarczyk, Anna Ronowska, Agnieszka Jankowska-Kulawy, Andrzej Szutowicz
Publikováno v:
Pharmacological Reports. 63:1272-1273