Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Aleksandra Bebel"'
Publikováno v:
eLife, Vol 9 (2020)
Mobile genetic elements (MGEs) are a rich source of new enzymes, and conversely, understanding the activities of MGE-encoded proteins can elucidate MGE function. Here, we biochemically characterize three proteins encoded by a conserved operon carried
Externí odkaz:
https://doaj.org/article/0da69d8b640b47dabe556adea1980bef
Publikováno v:
eLife, Vol 5 (2016)
Bacterial Xer site-specific recombinases play an essential genome maintenance role by unlinking chromosome multimers, but their mechanism of action has remained structurally uncharacterized. Here, we present two high-resolution structures of Helicoba
Externí odkaz:
https://doaj.org/article/cc02f1a8843444c5a9a72ff87df08c89
Publikováno v:
eLife, Vol 9 (2020)
Mobile genetic elements (MGEs) are a rich source of new enzymes, and conversely, understanding the activities of MGE-encoded proteins can elucidate MGE function. Here, we biochemically characterize three proteins encoded by a conserved operon carried
Autor:
Banushree Kumar, Alison B. Hickman, Michael Chandler, Catherine Guynet, Natalia Rosalía Morero, Sachi Okamoto, Orsolya Barabas, Cecilia Zuliani, Aleksandra Bebel, Fred Dyda
Publikováno v:
Nucleic Acids Research
'Nucleic Acids Research ', vol: 46, pages: 4152-4163 (2018)
'Nucleic Acids Research ', vol: 46, pages: 4152-4163 (2018)
Transposable elements are efficient DNA carriers and thus important tools for transgenesis and insertional mutagenesis. However, their poor target sequence specificity constitutes an important limitation for site-directed applications. The insertion
Autor:
Lotte Lambertsen, Georgy Smyshlyaev, Orsolya Barabas, Aleksandra Bebel, Eike C. Schulz, Peer Bork, Carlos Rojas-Cordova, Kristoffer Forslund, Anna Rubio-Cosials, Ezgi Karaca
Publikováno v:
Cell
Cell 173(1), 208-220 (2018). doi:10.1016/j.cell.2018.02.032
Cell 173(1), 208-220 (2018). doi:10.1016/j.cell.2018.02.032
Summary Conjugative transposition drives the emergence of multidrug resistance in diverse bacterial pathogens, yet the mechanisms are poorly characterized. The Tn1549 conjugative transposon propagates resistance to the antibiotic vancomycin used for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0b15fced5d513dc176750a0dbb62fd5
Publikováno v:
'eLife ', vol: 5, pages: e19706-1-e19706-23 (2016)
eLife, Vol 5 (2016)
eLife
eLife, Vol 5 (2016)
eLife
Bacterial Xer site-specific recombinases play an essential genome maintenance role by unlinking chromosome multimers, but their mechanism of action has remained structurally uncharacterized. Here, we present two high-resolution structures of Helicoba
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38f6468d6b7aa7ee0ccfdcec106530ad
https://avesis.deu.edu.tr/publication/details/7a61a9a3-db75-4fe1-8bb5-097983e332d4/oai
https://avesis.deu.edu.tr/publication/details/7a61a9a3-db75-4fe1-8bb5-097983e332d4/oai
Publikováno v:
Breast Cancer Research : BCR
Introduction Two major high-penetrance breast cancer genes, BRCA1 and BRCA2, are responsible for approximately 20% of hereditary breast cancer (HBC) cases in Finland. Additionally, rare mutations in several other genes that interact with BRCA1 and BR