Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Aleksandra Babicheva"'
Autor:
Mingmei Xiong, Pritesh P. Jain, Jiyuan Chen, Aleksandra Babicheva, Tengteng Zhao, Mona Alotaibi, Nick H. Kim, Ning Lai, Amin Izadi, Marisela Rodriguez, Jifeng Li, Angela Balistrieri, Francesca Balistrieri, Sophia Parmisano, Xin Sun, Daniela Valdez‐Jasso, John Y‐J. Shyy, Patricia A. Thistlethwaite, Jian Wang, Ayako Makino, Jason X.‐J. Yuan
Publikováno v:
Pulmonary Circulation, Vol 11, Iss 4, Pp 1-17 (2021)
Pulmonary arterial hypertension is a progressive and fatal disease and rodents with experimental pulmonary hypertension (PH) are often used to study pathogenic mechanisms, identify therapeutic targets, and develop novel drugs for treatment. Here we d
Externí odkaz:
https://doaj.org/article/1cc8dfb4cf714cbb804698ca95dfda41
Autor:
Marisela Rodriguez, Jiyuan Chen, Pritesh P. Jain, Aleksandra Babicheva, Mingmei Xiong, Jifeng Li, Ning Lai, Tengteng Zhao, Moises Hernandez, Angela Balistrieri, Sophia Parmisano, Tatum Simonson, Ellen Breen, Daniela Valdez-Jasso, Patricia A. Thistlethwaite, John Y. -J. Shyy, Jian Wang, Joe G. N. Garcia, Ayako Makino, Jason X. -J. Yuan
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Excessive pulmonary artery (PA) smooth muscle cell (PASMC) proliferation and migration are implicated in the development of pathogenic pulmonary vascular remodeling characterized by concentric arterial wall thickening and arteriole muscularization in
Externí odkaz:
https://doaj.org/article/1995a8a050974260b9221a472c8505e7
Autor:
Pritesh P. Jain, Susumu Hosokawa, Mingmei Xiong, Aleksandra Babicheva, Tengteng Zhao, Marisela Rodriguez, Shamin Rahimi, Kiana Pourhashemi, Francesca Balistrieri, Ning Lai, Atul Malhotra, John Y.-J. Shyy, Daniela Valdez-Jasso, Patricia A. Thistlethwaite, Ayako Makino, Jason X.-J. Yuan
Publikováno v:
Pulmonary Circulation, Vol 10 (2020)
Hypoxic Pulmonary Vasoconstriction (HPV) is an important physiological mechanism of the lungs that matches perfusion to ventilation thus maximizing O 2 saturation of the venous blood within the lungs. This study emphasizes on principal pathways in th
Externí odkaz:
https://doaj.org/article/d3f232845d024d048532b4afcc9a8108
Autor:
Casey E. Romanoski, Xinshuai Qi, Shreya Sangam, Rebecca R. Vanderpool, Robert S. Stearman, Austin Conklin, Manuel Gonzalez-Garay, Franz Rischard, Ramon J. Ayon, Jian Wang, Tatum Simonson, Aleksandra Babicheva, Yinan Shi, Haiyang Tang, Ayako Makino, Yogendra Kanthi, Mark W. Geraci, Joe G.N. Garcia, Jason X.-J. Yuan, Ankit A. Desai
Publikováno v:
Pulmonary Circulation, Vol 10 (2020)
Using RNAseq, we identified a 61 gene-based circulating transcriptomic profile most correlated with four indices of pulmonary arterial hypertension severity. In an independent dataset, 13/61 (21%) genes were differentially expressed in lung tissues o
Externí odkaz:
https://doaj.org/article/e546fc30e21247319e378d3c525325af
Autor:
Kang Wu, Haiyang Tang, Ruizhu Lin, Shane G. Carr, Ziyi Wang, Aleksandra Babicheva, Ramon J. Ayon, Pritesh P. Jain, Mingmei Xiong, Marisela Rodriguez, Shamin Rahimi, Francesca Balistrieri, Shayan Rahimi, Daniela Valdez-Jasso, Tatum S. Simonson, Ankit A. Desai, Joe G.N. Garcia, John Y.-J. Shyy, Patricia A. Thistlethwaite, Jian Wang, Ayako Makino, Jason X.-J. Yuan
Publikováno v:
Pulmonary Circulation, Vol 10 (2020)
Platelet-derived growth factor is one of the major growth factors found in human and mammalian serum and tissues. Abnormal activation of platelet-derived growth factor signaling pathway through platelet-derived growth factor receptors may contribute
Externí odkaz:
https://doaj.org/article/e8aacfe17c21472f9cda3af4d960ce7d
Autor:
Benoît Ranchoux, Lloyd D. Harvey, Ramon J. Ayon, Aleksandra Babicheva, Sebastien Bonnet, Stephen Y. Chan, Jason X.-J. Yuan, Vinicio de Jesus Perez
Publikováno v:
Pulmonary Circulation, Vol 8 (2018)
Endothelial dysfunction is a major player in the development and progression of vascular pathology in pulmonary arterial hypertension (PAH), a disease associated with small vessel loss and obstructive vasculopathy that leads to increased pulmonary va
Externí odkaz:
https://doaj.org/article/98de1057012f4a30b7b0c00cc1dc8bee
Autor:
Francesca Balistrieri, Jason X.-J. Yuan, Haiyang Tang, Xiaomin Wu, Tengteng Zhao, Ziyi Wang, Stephen M. Black, Aleksandra Babicheva, Ankit A. Desai, Jiyuan Chen, Pritesh P. Jain, Ramon J. Ayon, Daniela Valdez-Jasso, Joe G.N. Garcia, Ayako Makino, Marisela Rodriguez, Linda Wu, Keeley S. Ravellette, Jian Wang, John Y.-J. Shyy, Patricia A. Thistlethwaite, Xin Sun
Publikováno v:
Am J Physiol Cell Physiol
Piezo is a mechanosensitive cation channel responsible for stretch-mediated Ca2+ and Na+ influx in multiple types of cells. Little is known about the functional role of Piezo1 in the lung vasculature and its potential pathogenic role in pulmonary art
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7baebf821b4c32c93ea1d97ae6db0c72
https://doi.org/10.1152/ajpcell.00147.2021
https://doi.org/10.1152/ajpcell.00147.2021
Autor:
Amin Izadi, Marisela Rodriguez, Nick H. Kim, Ning Lai, Jian Wang, Sophia Parmisano, Pritesh P. Jain, Mingmei Xiong, Patricia A. Thistlethwaite, Xin Sun, Jiyuan Chen, Aleksandra Babicheva, Ayako Makino, John Y.-J. Shyy, Mona Alotaibi, Daniela Voldez-Jasso, Jifeng Li, Angela Balistrieri, Francesca Balistrieri, Tengteng Zhao, Jason X.-J. Yuan
Publikováno v:
Pulmonary circulation, vol 11, iss 4
Pulmonary Circulation
Pulmonary Circulation, Vol 11 (2021)
Pulmonary Circulation
Pulmonary Circulation, Vol 11 (2021)
Pulmonary arterial hypertension is a progressive and fatal disease and rodents with experimental pulmonary hypertension (PH) are often used to study pathogenic mechanisms, identify therapeutic targets, and develop novel drugs for treatment. Here we d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef9c9e96a1feff2e57f80b259ad49f6c
https://doi.org/10.1177/20458940211041512
https://doi.org/10.1177/20458940211041512
Autor:
Shamin Rahimi, Marisela Rodriguez, Ayako Makino, John Y.-J. Shyy, Ning Lai, Jiyuan Chen, Patricia A. Thistlethwaite, Mingmei Xiong, Francesca Balistrieri, Tengteng Zhao, Shane G. Carr, Jian Wang, Aleksandra Babicheva, Shayan Rahimi, Qiuyu Zheng, Shanshan Song, Tatum S. Simonson, Jason X.-J. Yuan, Pritesh P. Jain, Amin Izadi, Daniela Valdez-Jasso
Publikováno v:
Br J Pharmacol
British journal of pharmacology, vol 178, iss 17
British journal of pharmacology, vol 178, iss 17
BACKGROUND AND PURPOSE: Halofuginone is a febrifugine derivative originally isolated from Chinese traditional herb Chang Shan that exhibits anti-hypertrophic, anti-fibrotic and anti-proliferative effects. We sought to investigate whether halofuginone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::499ef3d96595495d79afa1e34ae53292
https://doi.org/10.1111/bph.15442
https://doi.org/10.1111/bph.15442
Autor:
Pritesh P, Jain, Susumu, Hosokawa, Aleksandra, Babicheva, Tengteng, Zhao, Jiyuan, Chen, Patricia A, Thistlethwaite, Ayako, Makino, Jason X-J, Yuan
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2472
Pulmonary arterial hypertension (PAH) is a severe disease characterized by sustained vasoconstriction, concentric wall thickening and vascular remodeling leading to increased pulmonary vascular resistance, causing right heart failure and death. Acute
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::45ee39c6ca6b66cf4ef6306207baeea2
https://pubmed.ncbi.nlm.nih.gov/35674903
https://pubmed.ncbi.nlm.nih.gov/35674903