Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Aleksandra, Wojtala"'
Autor:
Olga Alster, Anna Bielak-Zmijewska, Grazyna Mosieniak, Maria Moreno-Villanueva, Wioleta Dudka-Ruszkowska, Aleksandra Wojtala, Monika Kusio-Kobiałka, Zbigniew Korwek, Alexander Burkle, Katarzyna Piwocka, Jan K Siwicki, Ewa Sikora
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e104964 (2014)
Nibrin plays an important role in the DNA damage response (DDR) and DNA repair. DDR is a crucial signaling pathway in apoptosis and senescence. To verify whether truncated nibrin (p70), causing Nijmegen Breakage Syndrome (NBS), is involved in DDR and
Externí odkaz:
https://doaj.org/article/113bedff0d2a48deac13c1fd2b904068
Autor:
Merel J W, Adjobo-Hermans, Ria, de Haas, Peter H G M, Willems, Aleksandra, Wojtala, Sjenet E, van Emst-de Vries, Jori A, Wagenaars, Mariel, van den Brand, Richard J, Rodenburg, Jan A M, Smeitink, Leo G, Nijtmans, Leonid A, Sazanov, Mariusz R, Wieckowski, Werner J H, Koopman
Publikováno v:
Biochimica et biophysica acta. Bioenergetics. 1861(8)
Mutations in NDUFS4, which encodes an accessory subunit of mitochondrial oxidative phosphorylation (OXPHOS) complex I (CI), induce Leigh syndrome (LS). LS is a poorly understood pediatric disorder featuring brain-specific anomalies and early death. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::17f057b315e2d62d5f878aaa0c00d4c5
https://pubmed.ncbi.nlm.nih.gov/32335026
https://pubmed.ncbi.nlm.nih.gov/32335026
Autor:
Leo G.J. Nijtmans, Mariël A.M. van den Brand, Jori A. L. Wagenaars, Leonid A. Sazanov, Werner J.H. Koopman, Jan A.M. Smeitink, Merel J. W. Adjobo-Hermans, Sjenet E. van Emst-de Vries, Mariusz R. Wieckowski, Richard J. Rodenburg, Peter H.G.M. Willems, Aleksandra Wojtala, Ria de Haas
Publikováno v:
Biochimica et Biophysica Acta. Bioenergetics, 1861
Biochimica et Biophysica Acta. Bioenergetics, 1861, 8
Biochimica et Biophysica Acta. Bioenergetics, 1861, 8
Mutations in NDUFS4, which encodes an accessory subunit of mitochondrial oxidative phosphorylation (OXPHOS) complex I (CI), induce Leigh syndrome (LS). LS is a poorly understood pediatric disorder featuring brain-specific anomalies and early death. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbeb3235af78648702b370eecd47a8b4
https://hdl.handle.net/2066/220251
https://hdl.handle.net/2066/220251
Autor:
Małgorzata Partyka, Mariusz R. Wieckowski, Monika Prill, Alain Sewer, Karolina Drabik, Julia Hoeng, Bernadeta Michalska, Jędrzej Szymański, Paulina Patalas-Krawczyk, Marco van der Toorn, Stephanie Johne, Jarosław Walczak, Jerzy Duszyński, Joanna Szczepanowska, Aleksandra Wojtala, Dominika Malinska, Manuel C. Peitsch, Karsta Luettich
Publikováno v:
Food and Chemical Toxicology. 115:1-12
Mitochondrial dysfunction caused by cigarette smoke is involved in the oxidative stress-induced pathology of airway diseases. Reducing the levels of harmful and potentially harmful constituents by heating rather than combusting tobacco may reduce mit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef086138bacf4d604ff36cddb887a5fb
https://doi.org/10.1016/j.fct.2018.02.013
https://doi.org/10.1016/j.fct.2018.02.013
Autor:
Aleksandra Wojtala, Vilma A. Sardão, Maciej Pronicki, Paweł Kowalski, Jerzy Duszyński, Mariusz R. Wieckowski, Joanna Szczepanowska, Agnieszka Karkucinska-Wieckowska
Publikováno v:
Mitochondrion. 37:62-79
The mitochondrial respiratory chain, and in particular, complex I, is a major source of reactive oxygen species (ROS) in cells. Elevated levels of ROS are associated with an imbalance between the rate of ROS formation and the capacity of the antioxid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f762356fd8804beec5f1627900a1433
https://doi.org/10.1016/j.mito.2017.07.002
https://doi.org/10.1016/j.mito.2017.07.002
Autor:
Aleksandra Wojtala, Paulo J. Oliveira, Mariusz R. Wieckowski, Ignacio Vega-Naredo, Susana F. Sampaio, Ana F. Branco
Publikováno v:
Archives of Toxicology. 90:1669-1684
The adaptor protein p66Shc modulates cellular redox status integrating oxidative stress with mitochondrial stress responses. Upon oxidative stress, p66Shc is translocated to mitochondria or mitochondria-associated membranes in a multi-step process, r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07c757948850af90a6600a6c36b2da5d
https://doi.org/10.1007/s00204-015-1583-9
https://doi.org/10.1007/s00204-015-1583-9
Autor:
Aleksandra Wojtala, Magdalena Lebiedzinska-Arciszewska, Mariusz R. Wieckowski, Paulo J. Oliveira, Cláudia M. Deus, Cátia V. Diogo
Publikováno v:
European journal of clinical investigation. 47(1)
Background Patients with diabetes are at a high risk of developing both micro- and macrovascular disease. Hyperglycaemia seems to be the main factor in the pathogenesis of diabetic cardiomyopathy, often based on increased oxidative stress. Carvedilol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf311e573786dc7320e4ad92a84883ab
https://pubmed.ncbi.nlm.nih.gov/27805735
https://pubmed.ncbi.nlm.nih.gov/27805735
Autor:
Małgorzata Partyka, Marco van der Toorn, Karsta Luettich, Mariusz R. Wieckowski, Jarosław Walczak, Julia Hoeng, Monika Pril, Bernadeta Michalska, Stephanie Johne, Manuel C. Peitsch, Jędrzej Szymański, Karolina Drabik, Joanna Szczepanowska, Paulina Patalas-Krawczyk, Jerzy Duszyński, Aleksandra Wojtala, Dominika Malinska
Publikováno v:
Toxicology Letters. 280:S261-S262
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::78056e5cafbfe5cdede403bbb24bc766
https://doi.org/10.1016/j.toxlet.2017.07.928
https://doi.org/10.1016/j.toxlet.2017.07.928
Autor:
Aleksandra, Wojtala, Massimo, Bonora, Dominika, Malinska, Paolo, Pinton, Jerzy, Duszynski, Mariusz R, Wieckowski
Publikováno v:
Methods in enzymology. 542
Mitochondria are considered one of the main sources of reactive oxygen species (ROS). The overgeneration of ROS can evoke an intracellular state of oxidative stress, leading to permanent cell damage. Thus, the intracellular accumulation of ROS may no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6d92f3e533af48964e10a7ae801ff95f
https://pubmed.ncbi.nlm.nih.gov/24862270
https://pubmed.ncbi.nlm.nih.gov/24862270
Autor:
Anna Bielak-Zmijewska, Wioleta Dudka-Ruszkowska, Katarzyna Piwocka, Zbigniew Korwek, Grazyna Mosieniak, Jan Konrad Siwicki, Aleksandra Wojtala, Ewa Sikora, Monika Kusio-Kobialka, Alexander Bürkle, Maria Moreno-Villanueva, Olga Alster
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e104964 (2014)
PLoS ONE
PLoS ONE
Nibrin plays an important role in the DNA damage response (DDR) and DNA repair. DDR is a crucial signaling pathway in apoptosis and senescence. To verify whether truncated nibrin (p70), causing Nijmegen Breakage Syndrome (NBS), is involved in DDR and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8c5204131c5684a7b9ac9b6b2eedb70
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/25119968/?tool=EBI
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/25119968/?tool=EBI