Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Aleksandra, Lawera"'
Autor:
Richard M. Salmon, Jingxu Guo, Jennifer H. Wood, Zhen Tong, John S. Beech, Aleksandra Lawera, Minmin Yu, David J. Grainger, Jill Reckless, Nicholas W. Morrell, Wei Li
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
The molecular basis of activin receptor-like kinase 1 (ALK1)-mediated endothelial bone morphogenetic protein (BMP) signalling is not fully understood. Here, the authors present crystal structures of the BMP10:ALK1 and prodomain-bound BMP9:ALK1 comple
Externí odkaz:
https://doaj.org/article/c95928c8f6c04cf69fb1889c1608aeab
Autor:
Guillaume Bompard, Juliette van Dijk, Julien Cau, Yoann Lannay, Guillaume Marcellin, Aleksandra Lawera, Siem van der Laan, Krzysztof Rogowski
Publikováno v:
Cell Reports, Vol 25, Iss 10, Pp 2866-2877.e5 (2018)
Summary: Tubulin glutamylation is a reversible posttranslational modification that accumulates on stable microtubules (MTs). While abnormally high levels of this modification lead to a number of disorders such as male sterility, retinal degeneration,
Externí odkaz:
https://doaj.org/article/60f5568afcb149a18d27eb9561072d9a
Autor:
Krzysztof Rogowski, Julien Cau, Juliette van Dijk, Aleksandra Lawera, Siem van der Laan, Guillaume Marcellin, Guillaume Bompard, Yoann Lannay
Publikováno v:
Cell Reports
Cell Reports, Elsevier Inc, 2018, 25 (10), pp.2866-2877.e5. ⟨10.1016/j.celrep.2018.10.095⟩
Cell Reports, Vol 25, Iss 10, Pp 2866-2877.e5 (2018)
Cell Reports, Elsevier Inc, 2018, 25 (10), pp.2866-2877.e5. ⟨10.1016/j.celrep.2018.10.095⟩
Cell Reports, Vol 25, Iss 10, Pp 2866-2877.e5 (2018)
Summary: Tubulin glutamylation is a reversible posttranslational modification that accumulates on stable microtubules (MTs). While abnormally high levels of this modification lead to a number of disorders such as male sterility, retinal degeneration,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd096ed1bfdeae978ebac674caf1d12f
https://hal.archives-ouvertes.fr/hal-01974905
https://hal.archives-ouvertes.fr/hal-01974905
Autor:
Nicholas W. Morrell, John Wharton, Richard M. Salmon, Matthias Haimel, Joshua Hodgson, Wei Li, Stefan Gräf, Aleksandra Lawera, Martin R. Wilkins, Charaka Hadinnapola, Marta Bleda, Emilia M. Swietlik, Paul D. Upton
Publikováno v:
Fundamental mechanisms of pulmonary arterial hypertension.
Most heritable cases of pulmonary arterial hypertension (PAH) are explained by mutations in BMPR2, which encodes the bone morphogenetic protein type 2 receptor (BMPR-II). Additionally, mutations in the endothelial type 1 receptor, ALK1, can cause PAH
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c54ed8cb2122b6505cbcc6d0a976a3c5
https://doi.org/10.1136/thorax-2018-212555.47
https://doi.org/10.1136/thorax-2018-212555.47
Autor:
He, Jiang, Richard M, Salmon, Paul D, Upton, Zhenquan, Wei, Aleksandra, Lawera, Anthony P, Davenport, Nicholas W, Morrell, Wei, Li
Publikováno v:
The Journal of Biological Chemistry
BMP10 is highly expressed in the developing heart and plays essential roles in cardiogenesis. BMP10 deletion in mice results in embryonic lethality because of impaired cardiac development. In adults, BMP10 expression is restricted to the right atrium
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cf010b21cc8ac5c067f1d62dc511d8cf
https://pubmed.ncbi.nlm.nih.gov/26631724
https://pubmed.ncbi.nlm.nih.gov/26631724
Autor:
Michel O. Steinmetz, Susana Montenegro Gouveia, Aleksandra Lawera, Anna Akhmanova, Srinivas Honnappa, Kurt Wüthrich, Neel Sarovar Bhavesh, Fred F. Damberger, Frederik J.A. van Rijssel, Ilya Grigoriev, Hatim Jawhari, Ilian Jelesarov, Rubén M. Buey, Anke Weisbrich, Fritz K. Winkler
Publikováno v:
Cell
Cell, 138(2), 366-376. Cell Press
Cell, 138(2), 366-376. Cell Press
SummaryMicrotubules are filamentous polymers essential for cell viability. Microtubule plus-end tracking proteins (+TIPs) associate with growing microtubule plus ends and control microtubule dynamics and interactions with different cellular structure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82e5f26976460cb09c1444dbb25efdc9
https://pubmed.ncbi.nlm.nih.gov/19632184
https://pubmed.ncbi.nlm.nih.gov/19632184