Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Aleksandr P. Kalinovskii"'
Autor:
Dmitry I. Osmakov, Lyudmila V. Onoprienko, Aleksandr P. Kalinovskii, Sergey G. Koshelev, Vasiliy N. Stepanenko, Yaroslav A. Andreev, Sergey A. Kozlov
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 3, p 1413 (2024)
Tafalgin (Taf) is a tetrapeptide opioid used in clinical practice in Russia as an analgesic drug for subcutaneous administration as a solution (4 mg/mL; concentration of 9 mM). We found that the acid-sensing ion channels (ASICs) are another molecular
Externí odkaz:
https://doaj.org/article/23f362f711884a8887f22259b01696cc
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 22, p 16514 (2023)
α-Amylase is a generally acknowledged molecular target of a distinct class of antidiabetic drugs named α-glucosidase inhibitors. This class of medications is scarce and rather underutilized, and treatment with current commercial drugs is accompanie
Externí odkaz:
https://doaj.org/article/abcde771b42747e4bd95879a09a9cd4d
Autor:
Aleksandr P. Kalinovskii, Anton P. Pushkarev, Anastasia D. Mikhailenko, Denis S. Kudryavtsev, Olga A. Belozerova, Vladimir I. Shmygarev, Oleg N. Yatskin, Yuliya V. Korolkova, Sergey A. Kozlov, Dmitry I. Osmakov, Alexander Popov, Yaroslav A. Andreev
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 17, p 13148 (2023)
Acid-sensing ion channels (ASICs) are proton-gated ion channels that mediate nociception in the peripheral nervous system and contribute to fear and learning in the central nervous system. Sevanol was reported previously as a naturally-occurring ASIC
Externí odkaz:
https://doaj.org/article/f1f45347b7d24bdb9c1bc4fdbb292d54
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 10, p 8601 (2023)
Transient receptor potential vanilloid subtype 3 (TRPV3) is an ion channel with a sensory function that is most abundantly expressed in keratinocytes and peripheral neurons. TRPV3 plays a role in Ca2+ homeostasis due to non-selective ionic conductivi
Externí odkaz:
https://doaj.org/article/d819333a08b049bf82b65733313f0121
Autor:
Dmitry I. Osmakov, Aleksandr P. Kalinovskii, Olga A. Belozerova, Yaroslav A. Andreev, Sergey A. Kozlov
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 11, p 6031 (2022)
Plant lignans exhibit a wide range of biological activities, which makes them the research objects of potential use as therapeutic agents. They provide diverse naturally-occurring pharmacophores and are available for production by chemical synthesis.
Externí odkaz:
https://doaj.org/article/d75e74a2f1404b569d230e5f2e80c3ed
Autor:
Aleksandr P. Kalinovskii, Dmitry I. Osmakov, Sergey G. Koshelev, Kseniya I. Lubova, Yuliya V. Korolkova, Sergey A. Kozlov, Yaroslav A. Andreev
Publikováno v:
Biology, Vol 11, Iss 2, p 167 (2022)
Human neuroblastoma SH-SY5Y is a prominent neurobiological tool used for studying neuropathophysiological processes. We investigated acid-sensing (ASIC) and transient receptor potential vanilloid-1 (TRPV1) and ankyrin-1 (TRPA1) ion channels present i
Externí odkaz:
https://doaj.org/article/b2dd2677bae149c180511be10f0fcb10