Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Aleksandr E. Rubtsov"'
Publikováno v:
Russian Journal of General Chemistry. 91:2025-2030
The hydrolysis of substituted 3-(thien-2-yl)imino-3H-furan-2-ones in the presence of trifluoroacetic acid afforded a series of substituted 4-oxo-2-thienylaminobut-2-enoic acids. Anti-inflammatory activity and acute toxicity of the obtained substitute
Publikováno v:
Russian Journal of General Chemistry. 91:1623-1628
A method for the synthesis of substituted 4-(het)aryl-4-oxo-2-thienylaminobut-2-enoic acids containing a nitrile substituent in the thiophene ring was proposed. Intramolecular cyclization of the obtained compounds in the presence of propionic anhydri
Autor:
Aleksandr E. Rubtsov, Andrei V. Malkov
Publikováno v:
Synthesis. 53:2559-2569
The sustained interest in the synthesis of new analogues of 2,2′-bipyridines is supported by the importance of compounds featuring bipyridine core in diverse areas of chemical, biomedical and materials research, which is relayed into the developmen
Autor:
Aleksandr E. Rubtsov, Andrei V. Malkov
Publikováno v:
Synlett. 32:1397-1405
Asymmetric crotylation has firmly earned a place among the set of valuable synthetic tools for stereoselective construction of carbon skeletons. For a long time the field was heavily dominated by reagents bearing stoichiometric chiral auxiliaries, bu
Autor:
Nikolay S. Kondratyev, Vladimir Yu. Vaganov, Yasuaki Fukazawa, S. A. Shipilovskikh, Andrei V. Malkov, Steven E. Wheeler, Aleksandr E. Rubtsov
Publikováno v:
Advanced Synthesis & Catalysis. 362:5467-5474
Publikováno v:
Russian Journal of General Chemistry. 90:943-947
The intramolecular cyclization of substituted 4-oxo-4-(het)aryl-2-(thiophen-2-ylamino)but-2-enoic acids in the presence of acetic or propionic anhydride afforded a series novel substituted 3-(thien-2-yl)iminofuran-2(3H)-ones.
Publikováno v:
Russian Journal of General Chemistry. 90:809-814
The recyclization of 2-{[5-aryl-2-oxofuran-3(2H)-ylidene]amino}thiophene-3-carboxylic acids with cyano-acetic acid derivatives in the presence of t-BuOK afforded potassium 1-cyano-3-{[5-R1-4-R2-3-(ethoxycarbonyl)-thiophen-2-yl]amino}-1-R3-5-oxo-5-ary
Publikováno v:
Russian Journal of General Chemistry. 90:583-589
2-{[5-Aryl-2-oxofuran-3(2H)-ylidene]amino}thiophene-3-carboxylic acid derivatives reacted with substituted amines to give new N-substituted 4-aryl-4-oxo-2-[(3-thiophen-2-yl)amino]but-2-enamides. Antinociceptive activity of the synthesized compounds w
Publikováno v:
Green Chemistry
A short synthesis of N-acetylcolchinol using a greener pathway is reported where all the redox steps, except for the asymmetric reduction, were carried out electrochemically, replacing protocols that employ stoichiometric hazardous reagents.
Publikováno v:
European Journal of Organic Chemistry. 2020:3317-3319
Deoxygenation of heteroaromatic N-oxides is commonly accomplished using chemical or enzymatic methods. In this work, we report on an expedient protocol for electrochemical reduction of pyridine N-oxide derivatives under mild conditions. A diverse ran