Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Aleksandr Dubrovskiy"'
Autor:
Andrew Allen, Thomas C. Harding, Andrew D. Simmons, Juswinder Singh, William Pao, Zoe Weaver, Jeff Etter, Terry Van Dyke, Mitch Raponi, Sarah Jaw-Tsai, Kevin Lin, William Westlin, Russell C. Petter, Mariana Nacht, Deqiang Niu, Prasoon Chaturvedi, Dan van Kalken, Russell Karp, Thia St Martin, Michael Sheets, Zhigang Wang, Zhendong Zhu, Matthew Labenski, Aleksandr Dubrovskiy, Kwangho Lee, Jing Sun, Kadoaki Ohashi, Henry J. Haringsma, Robert Tjin Tham Sjin, Annette O. Walter
Supplementary Figure 10 - PDF file 333K, Analysis of multiple EGFR-related signaling pathways in parental NCI-H1975 and COR resistant clones by Western blotting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02218769c548c4860660a91b6fa35b2e
https://doi.org/10.1158/2159-8290.22530312.v1
https://doi.org/10.1158/2159-8290.22530312.v1
Autor:
Andrew Allen, Thomas C. Harding, Andrew D. Simmons, Juswinder Singh, William Pao, Zoe Weaver, Jeff Etter, Terry Van Dyke, Mitch Raponi, Sarah Jaw-Tsai, Kevin Lin, William Westlin, Russell C. Petter, Mariana Nacht, Deqiang Niu, Prasoon Chaturvedi, Dan van Kalken, Russell Karp, Thia St Martin, Michael Sheets, Zhigang Wang, Zhendong Zhu, Matthew Labenski, Aleksandr Dubrovskiy, Kwangho Lee, Jing Sun, Kadoaki Ohashi, Henry J. Haringsma, Robert Tjin Tham Sjin, Annette O. Walter
Supplementary Figure 6 - PDF file 112K, Impact of CO-1686, erlotinib and afatinib administration on mouse body-weight
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::beb439fd0e027237f4641c54439c0817
https://doi.org/10.1158/2159-8290.22530294
https://doi.org/10.1158/2159-8290.22530294
Autor:
Andrew Allen, Thomas C. Harding, Andrew D. Simmons, Juswinder Singh, William Pao, Zoe Weaver, Jeff Etter, Terry Van Dyke, Mitch Raponi, Sarah Jaw-Tsai, Kevin Lin, William Westlin, Russell C. Petter, Mariana Nacht, Deqiang Niu, Prasoon Chaturvedi, Dan van Kalken, Russell Karp, Thia St Martin, Michael Sheets, Zhigang Wang, Zhendong Zhu, Matthew Labenski, Aleksandr Dubrovskiy, Kwangho Lee, Jing Sun, Kadoaki Ohashi, Henry J. Haringsma, Robert Tjin Tham Sjin, Annette O. Walter
Supplementary Figure 9 - PDF file 168K, NCI-H1975 parental and CO-1686 resistant clones cluster into distinct groups using an RNA-based EMT signature
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2aeaa7d1b613eaaf35d748e107d61faf
https://doi.org/10.1158/2159-8290.22530285.v1
https://doi.org/10.1158/2159-8290.22530285.v1
Autor:
Andrew Allen, Thomas C. Harding, Andrew D. Simmons, Juswinder Singh, William Pao, Zoe Weaver, Jeff Etter, Terry Van Dyke, Mitch Raponi, Sarah Jaw-Tsai, Kevin Lin, William Westlin, Russell C. Petter, Mariana Nacht, Deqiang Niu, Prasoon Chaturvedi, Dan van Kalken, Russell Karp, Thia St Martin, Michael Sheets, Zhigang Wang, Zhendong Zhu, Matthew Labenski, Aleksandr Dubrovskiy, Kwangho Lee, Jing Sun, Kadoaki Ohashi, Henry J. Haringsma, Robert Tjin Tham Sjin, Annette O. Walter
Supplementary Figure 3 - PDF file 295K, Activity of CO-1686 against rare lung-cancer associated EGFR mutants
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75554071bcf856b9ed15932b3ea11f64
https://doi.org/10.1158/2159-8290.22530303
https://doi.org/10.1158/2159-8290.22530303
Autor:
Juswinder Singh, Andrew Allen, Russell C. Petter, William F. Westlin, Mariana Nacht, Deqiang Niu, Thomas C. Harding, Andrew D. Simmons, Mitch Raponi, Jeff Etter, Henry Haringsma, Yixuan Ren, Prasoon Chaturvedi, Aravind Medikonda, Russell Karp, Richland Tester, Zhendong Zhu, Matthew T. Labenski, Thia St. Martin, Michael Sheets, Aleksandr Dubrovskiy, Annette O. Walter, Kwangho Lee, Robert Tjin Tham Sjin
PDF - 252K, Supplemental Table 1. Mass spectrometry on EGFR-L858R/T790M protein. Supplemental Table 2. EGFR modulation in A431, H1975 and HCC827 cells by compound 3. Supplemental Table 3. Kinase selectivity profile of compound 3, afatinib and WZ4002
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7affe8de12460b3179d7242aec74389b
https://doi.org/10.1158/1535-7163.22500919.v1
https://doi.org/10.1158/1535-7163.22500919.v1
Autor:
Andrew Allen, Thomas C. Harding, Andrew D. Simmons, Juswinder Singh, William Pao, Zoe Weaver, Jeff Etter, Terry Van Dyke, Mitch Raponi, Sarah Jaw-Tsai, Kevin Lin, William Westlin, Russell C. Petter, Mariana Nacht, Deqiang Niu, Prasoon Chaturvedi, Dan van Kalken, Russell Karp, Thia St Martin, Michael Sheets, Zhigang Wang, Zhendong Zhu, Matthew Labenski, Aleksandr Dubrovskiy, Kwangho Lee, Jing Sun, Kadoaki Ohashi, Henry J. Haringsma, Robert Tjin Tham Sjin, Annette O. Walter
Supplementary Table 1 - PDF file 114K, Kinase selectivity profiling of CO-1686
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a996a50c7f90ac2361cf9617ff1c04b
https://doi.org/10.1158/2159-8290.22530279
https://doi.org/10.1158/2159-8290.22530279
Autor:
Andrew Allen, Thomas C. Harding, Andrew D. Simmons, Juswinder Singh, William Pao, Zoe Weaver, Jeff Etter, Terry Van Dyke, Mitch Raponi, Sarah Jaw-Tsai, Kevin Lin, William Westlin, Russell C. Petter, Mariana Nacht, Deqiang Niu, Prasoon Chaturvedi, Dan van Kalken, Russell Karp, Thia St Martin, Michael Sheets, Zhigang Wang, Zhendong Zhu, Matthew Labenski, Aleksandr Dubrovskiy, Kwangho Lee, Jing Sun, Kadoaki Ohashi, Henry J. Haringsma, Robert Tjin Tham Sjin, Annette O. Walter
Supplementary Figure 1 - PDF file 596K, Covalent binding of the EGFR L858R/T790M protein by CO-1686
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06a5919bc2df40bc58a9680b0410a455
https://doi.org/10.1158/2159-8290.22530315
https://doi.org/10.1158/2159-8290.22530315
Autor:
Juswinder Singh, Andrew Allen, Russell C. Petter, William F. Westlin, Mariana Nacht, Deqiang Niu, Thomas C. Harding, Andrew D. Simmons, Mitch Raponi, Jeff Etter, Henry Haringsma, Yixuan Ren, Prasoon Chaturvedi, Aravind Medikonda, Russell Karp, Richland Tester, Zhendong Zhu, Matthew T. Labenski, Thia St. Martin, Michael Sheets, Aleksandr Dubrovskiy, Annette O. Walter, Kwangho Lee, Robert Tjin Tham Sjin
Patients with non–small cell lung carcinoma (NSCLC) with activating mutations in epidermal growth factor receptor (EGFR) initially respond well to the EGFR inhibitors erlotinib and gefitinib. However, all patients relapse because of the emergence o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d89207d966fd9c58b6d3754ffc7f3533
https://doi.org/10.1158/1535-7163.c.6536629.v1
https://doi.org/10.1158/1535-7163.c.6536629.v1
Autor:
Andrew Allen, Thomas C. Harding, Andrew D. Simmons, Juswinder Singh, William Pao, Zoe Weaver, Jeff Etter, Terry Van Dyke, Mitch Raponi, Sarah Jaw-Tsai, Kevin Lin, William Westlin, Russell C. Petter, Mariana Nacht, Deqiang Niu, Prasoon Chaturvedi, Dan van Kalken, Russell Karp, Thia St Martin, Michael Sheets, Zhigang Wang, Zhendong Zhu, Matthew Labenski, Aleksandr Dubrovskiy, Kwangho Lee, Jing Sun, Kadoaki Ohashi, Henry J. Haringsma, Robert Tjin Tham Sjin, Annette O. Walter
Supplementary Figure 7 - PDF file 352K, H&E and immunohistochemical (Ki67) staining of tumors derived from EGFR mutant GEM models
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08736f46766b6b458998216dab88bde2
https://doi.org/10.1158/2159-8290.22530291
https://doi.org/10.1158/2159-8290.22530291
Autor:
Andrew Allen, Thomas C. Harding, Andrew D. Simmons, Juswinder Singh, William Pao, Zoe Weaver, Jeff Etter, Terry Van Dyke, Mitch Raponi, Sarah Jaw-Tsai, Kevin Lin, William Westlin, Russell C. Petter, Mariana Nacht, Deqiang Niu, Prasoon Chaturvedi, Dan van Kalken, Russell Karp, Thia St Martin, Michael Sheets, Zhigang Wang, Zhendong Zhu, Matthew Labenski, Aleksandr Dubrovskiy, Kwangho Lee, Jing Sun, Kadoaki Ohashi, Henry J. Haringsma, Robert Tjin Tham Sjin, Annette O. Walter
Supplementary Figure 8 - PDF file 215K, Photomicrographs of CO-1686 resistant NCI-H1975 cell (COR) clones and quantification of EGFR siRNA knockdown in COR clones
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4558e00df39d04afcabb13b864c93047
https://doi.org/10.1158/2159-8290.22530288
https://doi.org/10.1158/2159-8290.22530288