Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Aleksander Tworak"'
Autor:
Arum Wu, David Salom, John D. Hong, Aleksander Tworak, Kohei Watanabe, Els Pardon, Jan Steyaert, Hideki Kandori, Kota Katayama, Philip D. Kiser, Krzysztof Palczewski
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Rhodopsin is a prototypical G protein-coupled receptor (GPCR) critical for vertebrate vision. Research on GPCR signaling states has been facilitated using llama-derived nanobodies (Nbs), some of which bind to the intracellular surface to all
Externí odkaz:
https://doaj.org/article/9900f7db38c8485ebcda5ceda5533a76
Autor:
Aleksander Tworak, Alexander V. Kolesnikov, John D. Hong, Elliot H. Choi, Jennings C. Luu, Grazyna Palczewska, Zhiqian Dong, Dominik Lewandowski, Matthew J. Brooks, Laura Campello, Anand Swaroop, Philip D. Kiser, Vladimir J. Kefalov, Krzysztof Palczewski
Publikováno v:
Cell Reports, Vol 42, Iss 8, Pp 112982- (2023)
Summary: In daylight, demand for visual chromophore (11-cis-retinal) exceeds supply by the classical visual cycle. This shortfall is compensated, in part, by the retinal G-protein-coupled receptor (RGR) photoisomerase, which is expressed in both the
Externí odkaz:
https://doaj.org/article/d81d281593bd407d80bcbeef11c89b36
Autor:
Dominik Lewandowski, Andrzej T. Foik, Roman Smidak, Elliot H. Choi, Jianye Zhang, Thanh Hoang, Aleksander Tworak, Susie Suh, Henri Leinonen, Zhiqian Dong, Antonio F.M. Pinto, Emily Tom, Jennings Luu, Joan Lee, Xiuli Ma, Erhard Bieberich, Seth Blackshaw, Alan Saghatelian, David C. Lyon, Dorota Skowronska-Krawczyk, Marcin Tabaka, Krzysztof Palczewski
Publikováno v:
JCI Insight, Vol 7, Iss 4 (2022)
Adiponectin receptor 1 (ADIPOR1) is a lipid and glucose metabolism regulator that possesses intrinsic ceramidase activity. Mutations of the ADIPOR1 gene have been associated with nonsyndromic and syndromic retinitis pigmentosa. Here, we show that the
Externí odkaz:
https://doaj.org/article/d6761896c71d4db8902de4c695125400
Autor:
Philip D. Kiser, Thanh Hoang, David Salom, X. Krzysztof Palczewski, Aleksander Tworak, Christopher L. Sander, Jianye Zhang, Henri Leinonen, X. Seth Blackshaw, Grazyna Palczewska, James T. Handa, Elliot H. Choi
Publikováno v:
Journal of Biological Chemistry. 294:19137-19154
Photoisomerization of the 11-cis-retinal chromophore of rod and cone visual pigments to an all-trans-configuration is the initiating event for vision in vertebrates. The regeneration of 11-cis-retinal, necessary for sustained visual function, is an e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::710cf5cd45ea93c7eec02b33f2f64dbb
https://doi.org/10.1074/jbc.ra119.011169
https://doi.org/10.1074/jbc.ra119.011169
Autor:
Dominik Lewandowski, Andrzej T. Foik, Roman Smidak, Elliot H. Choi, Jianye Zhang, Thanh Hoang, Aleksander Tworak, Susie Suh, Henri Leinonen, Zhiqian Dong, Antonio F.M. Pinto, Emily Tom, Jennings Luu, Joan Lee, Xiuli Ma, Erhard Bieberich, Seth Blackshaw, Alan Saghatelian, David C. Lyon, Dorota Skowronska-Krawczyk, Marcin Tabaka, Krzysztof Palczewski
Publikováno v:
JCI insight, vol 7, iss 4
Adiponectin receptor 1 (ADIPOR1) is a lipid and glucose metabolism regulator that possesses intrinsic ceramidase activity. Mutations of the ADIPOR1 gene have been associated with nonsyndromic and syndromic retinitis pigmentosa. Here, we show that the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0316abd60945766526c84fec1399d774
https://pubmed.ncbi.nlm.nih.gov/35015730
https://pubmed.ncbi.nlm.nih.gov/35015730
Autor:
Dominik Lewandowski, Christopher L. Sander, Aleksander Tworak, Fangyuan Gao, Qianlan Xu, Dorota Skowronska-Krawczyk
Publikováno v:
Progress in retinal and eye research. 89
The retinal pigment epithelium-photoreceptor interphase is renewed each day in a stunning display of cellular interdependence. While photoreceptors use photosensitive pigments to convert light into electrical signals, the RPE supports photoreceptors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38ce91e807f68e230ed222be83348747
https://pubmed.ncbi.nlm.nih.gov/34971765
https://pubmed.ncbi.nlm.nih.gov/34971765
Autor:
Jianye, Zhang, Elliot H, Choi, Aleksander, Tworak, David, Salom, Henri, Leinonen, Christopher L, Sander, Thanh V, Hoang, James T, Handa, Seth, Blackshaw, Grazyna, Palczewska, Philip D, Kiser, Krzysztof, Palczewski
Publikováno v:
J Biol Chem
Photoisomerization of the 11-cis-retinal chromophore of rod and cone visual pigments to an all-trans-configuration is the initiating event for vision in vertebrates. The regeneration of 11-cis-retinal, necessary for sustained visual function, is an e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::da4fac48bc0e7b0b806d3c02a27a591c
https://pubmed.ncbi.nlm.nih.gov/31694912
https://pubmed.ncbi.nlm.nih.gov/31694912
Autor:
Agnieszka Mickiewicz, Anna Kurzynska-Kokorniak, Marek Figlerowicz, Maria Pokornowska, Anna Urbanowicz, Aleksander Tworak, Natalia Koralewska
Publikováno v:
Nucleic Acids Research
There is increasing evidence indicating that the production of small regulatory RNAs is not the only process in which ribonuclease Dicer can participate. For example, it has been demonstrated that this enzyme is also involved in chromatin structure r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ee3f39635116bf5d7d7e242014afb20
http://europepmc.org/articles/PMC4482082
http://europepmc.org/articles/PMC4482082
Publikováno v:
Acta Biochimica Polonica. 63
G-quadruplexes are non-canonical secondary structures which may be formed by guanine rich sequences, both in vitro and in living cells. The number of biological functions assigned to these structural motifs has grown rapidly since the discovery of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d37e5b07363f6c10422e97165b0b0fa
https://doi.org/10.18388/abp.2016_1335
https://doi.org/10.18388/abp.2016_1335
Publikováno v:
Scopus-Elsevier
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e62eebd7ceeb21b705a3a2cd74b73f4
https://doi.org/10.5114/bta.2013.46429
https://doi.org/10.5114/bta.2013.46429