Výsledky vyhledávání - "Aleksander Kirov"

Organ-specific lymphangiectasia, arrested lymphatic sprouting, and maturation defects resulting from gene-targeting of the PI3K regulatory isoforms p85α, p55α, and p50α

Autor: Maria Cecilia Mancini, Lewis C. Cantley, Philip E. Thorpe, Carla Mouta-Bellum, Lucy Liaw, Igor Prudovsky, Tatiana Petrova, David A. Fruman, Naoyuki Miura, Calvin P.H. Vary, Laura Miceli-Libby, Aleksander Kirov, Kari Alitalo

Publikováno v: Developmental Dynamics, vol. 238, no. 10, pp. 2670-2679

The phosphoinositide 3-kinase (PI3K) family has multiple vascular functions, but the specific regulatory isoform supporting lymphangiogenesis remains unidentified. Here, we report that deletion of the Pik3r1 gene, encoding the regulatory subunits p85

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad66e8f19fd069ad79a9fe1b41e41827
https://europepmc.org/articles/PMC2826787/

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