Zobrazeno 1 - 2
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pro vyhledávání: '"Aleksander Garabadzhiu"'
Autor:
Daria S. Novikova, Viacheslav G. Tribulovich, Aleksandra Sagaidak, Aleksander Garabadzhiu, Angelina Romanova, Tatyana A. Grigoreva
Publikováno v:
Chemico-biological interactions. 344
The problem of chemoresistance development is an inescapable flipside of modern oncotherapy, in particular for сolorectal cancer patients. The search for or development of drugs effective against resistant tumors involves the use of model resistant
Publikováno v:
E3S Web of Conferences, Vol 215, p 05005 (2020)
Reduced delivery of the drug into the cell due to increased activity of specific transporter P-glycoprotein is one of the main mechanisms of drug resistance development. The inhibition of the activity of such a pump increases the intracellular concen