Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Aleksander Dolashki"'
Autor:
Albena Alexandrova, Lubomir Petrov, Lyudmila Velkova, Aleksander Dolashki, Elina Tsvetanova, Almira Georgieva, Pavlina Dolashka
Publikováno v:
Journal of Pharmacy & Pharmacognosy Research, Vol 9, Iss 2, Pp 143-152 (2021)
Context: The snail hemolymph is a multi-component mixture comprising various substances with pharmacological activity. Aims: To evaluate the antioxidant activity of hemocyanin and fractions isolated of hemolymph from garden snail Helix lucorum.
Externí odkaz:
https://doaj.org/article/8f1fb3f7c01f44eebe5a164403f7e787
Autor:
Mihaela Belouhova, Elmira Daskalova, Ivaylo Yotinov, Yana Topalova, Lyudmila Velkova, Aleksander Dolashki, Pavlina Dolashka
Publikováno v:
MicrobiologyOpen, Vol 11, Iss 1, Pp n/a-n/a (2022)
Abstract The search for new natural compounds for application in medicine and cosmetics is a trend in biotechnology. One of the sources of such active compounds is the snail mucus. Snail physiology and the biological activity of their fluids (especia
Externí odkaz:
https://doaj.org/article/44ddb15edf64447cabcb710179143a30
Autor:
Lubomir Petrov, Mihail Kachaunov, Albena Alexandrova, Elina Tsvetanova, Almira Georgieva, Aleksander Dolashki, Lyudmila Velkova, Pavlina Dolashka
Publikováno v:
Life, Vol 12, Iss 8, p 1106 (2022)
Nowadays, an increased interest in natural compounds with preventive or therapeutic potential for various diseases has been observed. Given the involvement of oxidative stress in the pathogenesis of gastric ulcer (GU) and the wide range of bioactive
Externí odkaz:
https://doaj.org/article/0b38a3a0ef244e7584c07abd86706444
Autor:
Jozef Van Beeumen, Aleksander Dolashki, Matthias Floetenmeyer, Lyudmila Velkova, Pavlina Dolashka, Stefan Stevanovic, Wolfgang Voelter
Publikováno v:
Scopus-Elsevier
For the first time the antimicrobial activities of hemocyanins from the molluscs Rapana venosa (RvH) and Helix aspersa (HaH) have been tested. From the hemolymph of the garden snail H. aspersa one structural subunit (βc-HaH ) and eight functional un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b11d7624a63228789c66402390f00b9
https://doi.org/10.2174/1389201016666150907113435
https://doi.org/10.2174/1389201016666150907113435
Autor:
Aleksander Dolashki, Boris P. Atanasov, Pavlina Dolashka, Wolfgang Voelter, Lyudmila Velkova, Christian Betzel, Gita Subba Rao, Maria Angelova, Vesela Moshtanska
Publikováno v:
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy. 83:67-73
The native form of Cu/Zn-superoxide dismutase, isolated from fungal strain Humicola lutea 103 is a homodimer that coordinates one Cu(2+) and one Zn(2+) per monomer. Cu(2+) and Zn(2+) ions play crucial roles in enzyme activity and structural stability
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfa34cb33bdb79ad22f39c0f68009d14
https://doi.org/10.1016/j.saa.2011.07.048
https://doi.org/10.1016/j.saa.2011.07.048
Structural analysis and molecular modeling of the RvH2-e functional unit of Rapana venosa hemocyanin
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics. 1804:2177-2182
Rapana venosa hemocyanin (RvH), a circulating glycoprotein of the marine snail, has a complex structure. To provide details on the stability of the protein, one functional unit, RvH2-e, was compared with the native molecule and the structural subunit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99e27be69132563bec541da6c7c9284a
https://doi.org/10.1016/j.bbapap.2010.08.009
https://doi.org/10.1016/j.bbapap.2010.08.009
Autor:
Bernhard Lieb, Jozef Van Beeumen, Aleksander Dolashki, Bart Devreese, Angel S. Galabov, Lubomira Nikolaeva-Glomb, Pavlina Dolashka-Angelova, Nina Heilen, Koen Sandra, Stefan Stevanovic, Wolfgang Voelter, Ludmila Velkova
Publikováno v:
Bioconjugate Chemistry
Bioconjugate Chemistry, American Chemical Society, 2009, 20 (7), pp.1315-22. ⟨10.1021/bc900034k⟩
Bioconjugate Chemistry, American Chemical Society, 2009, 20 (7), pp.1315-22. ⟨10.1021/bc900034k⟩
International audience; Molluscan hemocyanins (Hcs) have recently received particular interest due to their significant immunostimulatory properties. This is mainly related to their high carbohydrate content and specific monosaccharide composition. W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62a340b031666b2d5ecb33f5afc5f16f
https://doi.org/10.1021/bc900034k
https://doi.org/10.1021/bc900034k
Autor:
Tzvetan Dimanov, Aleksander Dolashki, Valika Borisova, Pavlina Dolashka, Wolfgang Voelter, Vesela Moshtanska, Stefan Stevanovic
Publikováno v:
Peptides. 32(7)
Hemolymph of Rapana venosa snails is a complex mixture of biochemically and pharmacologically active components such as peptides and proteins. Antimicrobial peptides are gaining attention as antimicrobial alternatives to chemical food preservatives a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::371b059d021f732276afb73271f5dbc5
https://pubmed.ncbi.nlm.nih.gov/21703315
https://pubmed.ncbi.nlm.nih.gov/21703315
Autor:
Jozef Van Beeumen, Bart Devreese, Bernhard Lieb, Lyudmila Velkova, Aleksander Dolashki, Wolfgang Voelter, Pavlina Dolashka
Publikováno v:
Glycoconjugate journal. 28(6)
The oligosaccharide structures of the structural subunit HtH1 of Haliotis tuberculata hemocyanin (HtH) were studied by mass spectral sequence analysis of the glycans. The proposed structures are based on MALDI-TOF-MS data before and after treatment w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6aad6770c1bfb620e44a2aa1ef407d41
https://pubmed.ncbi.nlm.nih.gov/21660411
https://pubmed.ncbi.nlm.nih.gov/21660411
Autor:
Stoyan Shishkov, I.G. Dimitrov, Jozef Van Beeumen, Ludmyla Velkova, Bart Devreese, Kalina Kostova, Wolfgang Voelter, Aleksander Dolashki, Pavlina Dolashka, Boris P. Atanasov
Publikováno v:
Carbohydrate research. 345(16)
Molluscan hemocyanins are very large biological macromolecules and they act as oxygen-transporting glycoproteins. Most of them are glycoproteins with molecular mass around 9000 kDa. The oligosaccharide structures of the structural subunit RvH2 of Rap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92986b21ed02bfe753bb11c5dbc9fe1f
https://pubmed.ncbi.nlm.nih.gov/20863484
https://pubmed.ncbi.nlm.nih.gov/20863484