Zobrazeno 1 - 10 of 83 pro vyhledávání: '"Alekha K. Dash"'
1
Akademický článek
Transformation of dolutegravir into an ultra-long-acting parenteral prodrug formulation
Autor: Suyash Deodhar, Brady Sillman, Aditya N. Bade, Sean N. Avedissian, Anthony T. Podany, JoEllyn M. McMillan, Nagsen Gautam, Brandon Hanson, Bhagya L. Dyavar Shetty, Adam Szlachetka, Morgan Johnston, Michellie Thurman, Daniel J. Munt, Alekha K. Dash, Milica Markovic, Arik Dahan, Yazen Alnouti, Alborz Yazdi, Bhavesh D. Kevadiya, Siddappa N. Byrareddy, Samuel M. Cohen, Benson Edagwa, Howard E. Gendelman
Publikováno v: Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Here, using animal models, Deodhar et al. single parenteral dose of dolutegravir (DTG) prodrug nanocrystals sustains drug protein-adjusted 90% inhibitory concentration for up to a year, without injection site reactions or systemic toxicities.
Externí odkaz: https://doaj.org/article/0e6c6ddce7834d67b915c46f752da67f
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3
Akademický článek
Injectable Nano Drug Delivery Systems for the Treatment of Breast Cancer
Autor: Urmila Kafle, Satish Agrawal, Alekha K. Dash
Publikováno v: Pharmaceutics, Vol 14, Iss 12, p 2783 (2022)
Breast cancer is the most diagnosed type of cancer, with 2.26 million cases and 685,000 deaths recorded in 2020. If left untreated, this deadly disease can metastasize to distant organs, which is the reason behind its incurability and related deaths.
Externí odkaz: https://doaj.org/article/a00751439a6042bfa4da1da37cc9fde2
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4
Akademický článek
The effects of phosphocreatine disodium salts plus blueberry extract supplementation on muscular strength, power, and endurance
Autor: John Paul V. Anders, Tyler J. Neltner, Robert W. Smith, Joshua L. Keller, Terry J. Housh, F. Joseph Daugherty, Michael S. Tempesta, Alekha K. Dash, Daniel J. Munt, Richard J. Schmidt, Glen O. Johnson
Publikováno v: Journal of the International Society of Sports Nutrition, Vol 18, Iss 1 (2021)
Background Numerous studies have demonstrated the efficacy of creatine supplementation for improvements in exercise performance. Few studies, however, have examined the effects of phosphocreatine supplementation on exercise performance. Furthermore,
Externí odkaz: https://doaj.org/article/bff4dd5cc4d6457695910c4160334a97
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5
Akademický článek
The dark side of paclitaxel
Autor: Alekha K. Dash
Publikováno v: Oncology Reviews, Vol 4, Iss 2 (2011)
The bark extract of Pacific Yew (Taxus brevifolia) was first reported to have anti-tumor activity in 1963. The active constituent responsible for this activity was later identified in 1971 as paclitaxel [1]. Paclitaxel is a cytotoxic drug used in the
Externí odkaz: https://doaj.org/article/82716440e23140d1b45e2d74ae5ee537
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6
Injectable in situ gelling delivery system for the treatment of jawbone infections
Autor: Alekha K. Dash, Shreshtha Dash, Somnath Singh
Publikováno v: Therapeutic Delivery. 12:775-788
Aim: A polymeric in situ gelling delivery system for localized and sustained delivery to jawbone infections was developed. Materials & methods: In situ gelling delivery systems were prepared using either Poly(dl-lactic acid) or chitosan and Pluronic
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::aee5df763616bc8f0c7077bf43cee102
https://doi.org/10.4155/tde-2021-0054
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8
Liposomes and transferosomes: a breakthrough in topical and transdermal delivery
Autor: Alekha K. Dash, Rachana Sapkota
Publikováno v: Therapeutic Delivery. 12:145-158
The topical and transdermal routes of drug administration are long known to the field of pharmaceutics. These routes have been explored for the delivery of a wide range of therapeutic agents over centuries. However, the anatomy of the skin and the ph
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba29f08904c93b3e484ce1501f90b14b
https://doi.org/10.4155/tde-2020-0122
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9
Low-intensity light-induced drug release from a dual delivery system comprising of a drug loaded liposome and a photosensitive conjugate
Autor: I. G. Meerovich, Michael G. Nichols, Alekha K. Dash
Publikováno v: Journal of Drug Targeting. 28:655-667
This study reports the development of a binary drug delivery system consisting of charged liposomes and an oppositely charged peptide-photosensitiser conjugate. Liposomes were prepared with phosphatidyl-l-serine as a negatively charged lipid. Calcein
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aebf343f9fced8b1e74cba9ea84b2046
https://doi.org/10.1080/1061186x.2019.1710838
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