Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Alejandro Valdés-Jiménez"'
Autor:
Alejandro Valdés-Jiménez, Daniel Jiménez-González, Aytug K. Kiper, Susanne Rinné, Niels Decher, Wendy González, Miguel Reyes-Parada, Gabriel Núñez-Vivanco
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
The identification of similar three-dimensional (3D) amino acid patterns among different proteins might be helpful to explain the polypharmacological profile of many currently used drugs. Also, it would be a reasonable first step for the design of no
Externí odkaz:
https://doaj.org/article/197170dac86541658f2b64ec95dd9c6f
Publikováno v:
PLoS Computational Biology, Vol 18, Iss 2, p e1009703 (2022)
Is it possible to learn and create a first Hidden Markov Model (HMM) without programming skills or understanding the algorithms in detail? In this concise tutorial, we present the HMM through the 2 general questions it was initially developed to answ
Externí odkaz:
https://doaj.org/article/04990c9f4d1a4da4a95741ac5329b229
Autor:
Alejandro Valdés-Jiménez, Carlos Peña-Varas, Paola Borrego-Muñoz, Lily Arrue, Melissa Alegría-Arcos, Hussam Nour-Eldin, Ingo Dreyer, Gabriel Nuñez-Vivanco, David Ramírez
Publikováno v:
Molecules, Vol 26, Iss 4, p 1124 (2021)
Plants synthesize a large number of natural products, many of which are bioactive and have practical values as well as commercial potential. To explore this vast structural diversity, we present PSC-db, a unique plant metabolite database aimed to cat
Externí odkaz:
https://doaj.org/article/9c8c2e3aadb24e2fa6c5fe1a23fae48f
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 13, p 3174 (2019)
Discovering conserved three-dimensional (3D) patterns among protein structures may provide valuable insights into protein classification, functional annotations or the rational design of multi-target drugs. Thus, several computational tools have been
Externí odkaz:
https://doaj.org/article/e31ba9fb812e40ad8ddb7d947fab0ee5
Autor:
Julio Caballero, Gabriel Núñez-Vivanco, José Luis Velázquez-Libera, Alejandro Valdés-Jiménez, Fabio Durán-Verdugo
Publikováno v:
Bioinformatics. 36:2912-2914
Motivation Root mean square deviation (RMSD) is one of the most useful and straightforward features for structural comparison between different conformations of the same molecule. Commonly, protein-ligand docking programs have included some utilities
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3f0948afaceb2395f0ec8d916b00ac8
https://doi.org/10.1093/bioinformatics/btaa018
https://doi.org/10.1093/bioinformatics/btaa018
Publikováno v:
PLoS Computational Biology, Vol 18, Iss 2, p e1009703 (2022)
Is it possible to learn and create a first Hidden Markov Model (HMM) without programming skills or understanding the algorithms in detail? In this concise tutorial, we present the HMM through the 2 general questions it was initially developed to answ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61ee8fbeb1f96e3917fc384748ef2431
https://doi.org/10.1371/journal.pcbi.1009703
https://doi.org/10.1371/journal.pcbi.1009703
Publikováno v:
Proceedings of MOL2NET 2018, International Conference on Multidisciplinary Sciences, 4th edition.
Most of drugs interact with more than one molecular target. This fact typically would be seen like as an undesired feature of a pharmacological treatment, however, current trends in drug discovery has put hope and several efforts in the improved effi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::40e9a330daa2e793dfe4fcefde20ed27
https://doi.org/10.3390/mol2net-04-06009
https://doi.org/10.3390/mol2net-04-06009
Autor:
Gabriel Núñez-Vivanco, Alejandro Valdés-Jiménez, David Ramírez, Ingo Dreyer, Carlos Peña-Varas, Hussam Hassan Nour-Eldin, Lily Arrué, Paola Borrego-Muñoz, Melissa Alegría-Arcos
Publikováno v:
Valdes-Jimenez, A, Pena-Varas, C, Borrego-Munoz, P, Arrue, L, Alegria-Arcos, M, Nour-Eldin, H, Dreyer, I, Nunez-Vivanco, G & Ramirez, D 2021, ' PSC-db : A Structured and Searchable 3D-Database for Plant Secondary Compounds ', Molecules, vol. 26, no. 4, 1124 . https://doi.org/10.3390/molecules26041124
Molecules
Molecules, Vol 26, Iss 1124, p 1124 (2021)
Volume 26
Issue 4
Molecules
Molecules, Vol 26, Iss 1124, p 1124 (2021)
Volume 26
Issue 4
Plants synthesize a large number of natural products, many of which are bioactive and have practical values as well as commercial potential. To explore this vast structural diversity, we present PSC-db, a unique plant metabolite database aimed to cat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd816319210742a1921d80d6e0295f85
https://doi.org/10.3390/molecules26041124
https://doi.org/10.3390/molecules26041124
Autor:
Alejandro Valdés-Jiménez, Jose Antonio Reyes-Suarez, Roberto Ahumada-Garcia, Patricia Moller-Acuna
Publikováno v:
2017 CHILEAN Conference on Electrical, Electronics Engineering, Information and Communication Technologies (CHILECON).
Frosts are one of the main risks faced by farmers during the winter and spring seasons. These events can cause significant damage to cultivations and crops. In Chile, these frosts generate significant losses in the agricultural production sector, cau
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb1f8806ad5975844123efc9d497e2fb
https://doi.org/10.1109/chilecon.2017.8229595
https://doi.org/10.1109/chilecon.2017.8229595
Publikováno v:
O2, repositorio institucional de la UOC
Universitat Oberta de Catalunya (UOC)
Journal of Cheminformatics
Recercat. Dipósit de la Recerca de Catalunya
instname
Universitat Oberta de Catalunya (UOC)
Journal of Cheminformatics
Recercat. Dipósit de la Recerca de Catalunya
instname
Background Since the structure of proteins is more conserved than the sequence, the identification of conserved three-dimensional (3D) patterns among a set of proteins, can be important for protein function prediction, protein clustering, drug discov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc8336ddeed2582c58182bd6571301e0
http://hdl.handle.net/10609/78519
http://hdl.handle.net/10609/78519
