Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Alejandro V. Cano"'
Autor:
Alejandro V Cano, Joshua L Payne
Publikováno v:
PLoS Computational Biology, Vol 16, Iss 9, p e1008296 (2020)
Mutation is a biased stochastic process, with some types of mutations occurring more frequently than others. Previous work has used synthetic genotype-phenotype landscapes to study how such mutation bias affects adaptive evolution. Here, we consider
Externí odkaz:
https://doaj.org/article/08246e0d6e2f498397142e53875a0a5b
Autor:
Susanna Manrubia, José A. Cuesta, Jacobo Aguirre, Sebastian E. Ahnert, Lee Altenberg, Alejandro V. Cano, Pablo Catalán, Ramon Diaz-Uriarte, Santiago F. Elena, Juan Antonio García-Martín, Paulien Hogeweg, Bhavin S. Khatri, Joachim Krug, Ard A. Louis, Nora S. Martin, Joshua L. Payne, Matthew J. Tarnowski, Marcel Weiß
Publikováno v:
Physics of Life Reviews. 42:19-24
Publikováno v:
The American Naturalist.
The joint distribution of selection coefficients and mutation rates is a key determinant of the genetic architecture of molecular adaptation. Three different distributions are of immediate interest: (1) thenominaldistribution of possible changes, pri
Autor:
Alejandro V. Cano, Bryan L. Gitschlag, Hana Rozhoňová, Arlin Stoltzfus, David M. McCandlish, Joshua L. Payne
Publikováno v:
Philosophical Transactions of the Royal Society B: Biological Sciences, 378 (1877)
Predicting evolutionary outcomes is an important research goal in a diversity of contexts. The focus of evolutionary forecasting is usually on adaptive processes, and efforts to improve prediction typically focus on selection. However, adaptive proce
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 119 (7)
Evolutionary adaptation often occurs by the fixation of beneficial mutations. This mode of adaptation can be characterized quantitatively by a spectrum of adaptive substitutions, i.e., a distribution for types of changes fixed in adaptation. Recent w