Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Alejandro Torrado Pacheco"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Adolescence is characterized by increased impulsive and risk-taking behaviors. To better understand the neural networks that subserves impulsivity in adolescents, we used a reward-guided behavioral model that quantifies age differences in im
Externí odkaz:
https://doaj.org/article/193df6eda96d4089b8789f30b7f6b44e
Publikováno v:
bioRxiv
Psilocybin has been shown to improve symptoms of depression and anxiety when combined with psychotherapy or other clinician-guided interventions. To understand the neural basis for this pattern of clinical efficacy, experimental and conceptual approa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2b7e4b72053616cb1832297546e5d80
https://doi.org/10.1101/2023.01.09.523291
https://doi.org/10.1101/2023.01.09.523291
Publikováno v:
Neuron
Summary Homeostatic plasticity is hypothesized to bidirectionally regulate neuronal activity around a stable set point to compensate for learning-related plasticity, but to date only upward firing rate homeostasis (FRH) has been demonstrated in vivo.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::464459d76a16b10966be351d313f5601
https://pubmed.ncbi.nlm.nih.gov/33232655
https://pubmed.ncbi.nlm.nih.gov/33232655
SUMMARYHomeostatic plasticity is hypothesized to regulate neuronal activity around a stable set point to compensate for learning-related plasticity. This regulation is predicted to be bidirectional but only upward firing rate homeostasis (FRH) has be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf0b214982d97287a4f6b52ddd188561
https://doi.org/10.1101/827832
https://doi.org/10.1101/827832
Autor:
Brian J Lane, Elizabeth I Tilden, Julijana Gjorgjieva, Yue Wu, Alejandro Torrado Pacheco, Sophie M Grutzner, Keith B. Hengen, Gina G. Turrigiano
Publikováno v:
Proc Natl Acad Sci U S A
The dynamics of neuronal firing during natural vision are poorly understood. Surprisingly, mean firing rates of neurons in primary visual cortex (V1) of freely behaving rodents are similar during prolonged periods of light and darkness, but it is unk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfa410e7d728c94d2bf514cded5aa908
Autor:
Keith B. Hengen, James N. McGregor, Gina G. Turrigiano, Stephen D. Van Hooser, Alejandro Torrado Pacheco
Publikováno v:
Cell. 165:180-191
Homeostatic mechanisms stabilize neural circuit function by keeping firing rates within a set-point range, but whether this process is gated by brain state is unknown. Here, we monitored firing rate homeostasis in individual visual cortical neurons i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7e4a6d8833fcc9e87cf9d4b93688979
https://doi.org/10.1016/j.cell.2016.01.046
https://doi.org/10.1016/j.cell.2016.01.046
Autor:
Nathaniel J. Miska, Vedakumar Tatavarty, Stephen D. Van Hooser, Keith B. Hengen, Heather Lin, Alejandro Torrado Pacheco, Gina G. Turrigiano, Priya Koundinya, Chelsea Groves Kuhnle, Florence F. Wagner
Publikováno v:
Neuron
Summary Mutations in Shank3 are strongly associated with autism spectrum disorders and neural circuit changes in several brain areas, but the cellular mechanisms that underlie these defects are not understood. Homeostatic forms of plasticity allow ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd833f5bca0b2a4b82427afc48a7be2c
https://doi.org/10.1016/j.neuron.2020.02.033
https://doi.org/10.1016/j.neuron.2020.02.033