Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Alejandro Soto-Ospina"'
Autor:
Dubán González-Álvarez, Azucena Cabrera Jaramillo, Natalia Cadavid Muñoz, Diana María Agudelo-Echavarría, Alejandro Soto-Ospina, Álvaro Arango Ruiz
Publikováno v:
Emerging Contaminants, Vol 9, Iss 3, Pp 100230- (2023)
Thanks to their unique nutritional components, eggs constitute the source of nourishment for many people. Yet they can also absorb concentrations of several environmental contaminants. This study sought to assess the total mercury (THg) and methylmer
Externí odkaz:
https://doaj.org/article/87b0c0d8f4da42dd880cffe86c08ae30
Autor:
Natalia Cadavid Muñoz, Dubán González-Álvarez, Azucena Cabrera Jaramillo, Alejandro Soto-Ospina, Álvaro Arango Ruiz
Publikováno v:
Emerging Contaminants, Vol 9, Iss 2, Pp 100226- (2023)
Mercury (Hg), and its different chemical forms, such as methylmercury (MeHg), are highly toxic compounds that affect the environment as well as human and animal health. Specifically, mining practices may cause these metals to be present in water, air
Externí odkaz:
https://doaj.org/article/56439ae58958410fba4838380395efc2
Autor:
Alejandro Soto-Ospina, Pedronel Araque Marín, Gabriel Bedoya, Diego Sepulveda-Falla, Andrés Villegas Lanau
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
Alzheimer’s disease pathology is characterized by β-amyloid plaques and neurofibrillary tangles. Amyloid precursor protein is processed by β and γ secretase, resulting in the production of β-amyloid peptides with a length ranging from 38 to 43
Externí odkaz:
https://doaj.org/article/15a923f594e849cebec63e9a3c800d0f
Autor:
Juan Javier López-Rivera, Luna Rodríguez-Salazar, Alejandro Soto-Ospina, Carlos Estrada-Serrato, David Serrano, Henry Mauricio Chaparro-Solano, Olga Londoño, Paula A. Rueda, Geraldine Ardila, Andrés Villegas-Lanau, Marcela Godoy-Corredor, Mauricio Cuartas, Jorge I. Vélez, Oscar M. Vidal, Mario A. Isaza-Ruget, Mauricio Arcos-Burgos
Publikováno v:
Brain Sciences, Vol 12, Iss 7, p 871 (2022)
A whole-exome capture and next-generation sequencing was applied to an 11 y/o patient with a clinical history of congenital hypotonia, generalized motor and cognitive neurodevelopmental delay, and severe cognitive deficit, and without any identifiabl
Externí odkaz:
https://doaj.org/article/cf2108db75d04200bab42022ab155b2f
Autor:
Leydy Cano, Alejandro Soto-Ospina, Pedronel Araque, Maria Antonieta Caro-Gomez, Maria Victoria Parra-Marin, Gabriel Bedoya, Constanza Duque
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2021)
Metformin used as a first-line drug to treat Type 2 Diabetes Mellitus is transported via organic cation channels to soft tissues. Mutations in the SLC22A1 gene, such as Gly401Ser, Ser189Leu, and Arg206Cys, may affect the drug’s therapeutic effect o
Externí odkaz:
https://doaj.org/article/52f285a093574c5ca6b5597f92589c78
Publikováno v:
Biochemistry Research International, Vol 2021 (2021)
Alzheimer’s disease manifests itself in brain tissue by neuronal death, due to aggregation of β-amyloid, produced by senile plaques, and hyperphosphorylation of the tau protein, which produces neurofibrillary tangles. One of the genetic markers of
Externí odkaz:
https://doaj.org/article/f6084c25e8144715a749ada0e219900b
Autor:
Sandra M. Cardona, Sangwon V. Kim, Kaira A. Church, Vanessa O. Torres, Ian A. Cleary, Andrew S. Mendiola, Stephen P. Saville, Stephanie S. Watowich, Jan Parker-Thornburg, Alejandro Soto-Ospina, Pedronel Araque, Richard M. Ransohoff, Astrid E. Cardona
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 12 (2018)
Multiple sclerosis (MS), an inflammatory demyelinating disease of the central nervous system (CNS) is the leading cause of non-traumatic neurological disability in young adults. Immune mediated destruction of myelin and oligodendrocytes is considered
Externí odkaz:
https://doaj.org/article/76a2d98136d74fc3b8f720a970c7379d
Autor:
Yesid Alvarez Maya, Alejandro Soto-Ospina, Andrés Villegas-Lanau, Pedronel Araque, Carlos Andrés Naranjo, Esteban Uribe, Sol Jiménez, Elsa Vásquez, Gabriel de Jesús Bedoya, Margarita Velásquez
Publikováno v:
Revista de la Academia Colombiana de Ciencias Exactas, Físicas y Naturales. 47:8-21
La psoriasis es una enfermedad inflamatoria crónica inmunomediada en la que el eje IL-23/Th17 dirige el proceso patogénico. En la regulación del sistema inmunitario la propensión al desarrollo de la psoriasis en una población colombiana se asoci
Autor:
Alejandro Soto-Ospina, Álvaro Arango-Ruiz, Azucena Cabrera-Jaramillo, Dubán González-Álvarez, Natalia Cadavid-Muñoz
Publikováno v:
Producción + Limpia. 17:113-133
Las regiones en donde se presenta la minería aluvial de manera informal implican elevados niveles de mercurio en el entorno y, a su vez, graves afectaciones en la salud pública. El mercurio divalente se encuentra en solución acuosa en ríos y lago
Autor:
Andrés Villegas-Lanau, Andrés Puerta- González, Omer Campo-Nieto, Elías Cataño-Sánchez, Alejandro Soto-Ospina
Publikováno v:
Revista Lasallista de Investigación. 19:149-166
Introducción: Las placas amiloides son uno de los marcadores neuropatológicos de la enfermedad de Alzheimer, formadas por fragmentos peptídicos que se depositan, derivados del corte proteasa de la enzima γ-secretasa, de la cual presenilina-1 es l