Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Alejandro Sanz-Bravo"'
Autor:
Jose M. Honrubia, Javier Gutierrez-Álvarez, Alejandro Sanz-Bravo, Ezequiel González-Miranda, Diego Muñoz-Santos, Carlos Castaño-Rodriguez, Li Wang, Marta Villarejo-Torres, Jorge Ripoll-Gómez, Ana Esteban, Raul Fernandez-Delgado, Pedro José Sánchez-Cordón, Juan Carlos Oliveros, Stanley Perlman, Paul B. McCray, Isabel Sola, Luis Enjuanes
Publikováno v:
mBio, Vol 14, Iss 1 (2023)
ABSTRACT Coronaviruses (CoVs) of genera α, β, γ, and δ encode proteins that have a PDZ-binding motif (PBM) consisting of the last four residues of the envelope (E) protein (PBM core). PBMs may bind over 400 cellular proteins containing PDZ domain
Externí odkaz:
https://doaj.org/article/748cab695f5f46f68ab0f4651f18e0e3
Autor:
Luis Enjuanes, Isabel Sola, Sonia Zúñiga, José M. Honrubia, Melissa Bello-Pérez, Alejandro Sanz-Bravo, Ezequiel González-Miranda, Jesús Hurtado-Tamayo, Ricardo Requena-Platek, Li Wang, Diego Muñoz-Santos, Carlos M. Sánchez, Ana Esteban, Jorge Ripoll-Gómez
Publikováno v:
Current Research in Immunology, Vol 3, Iss , Pp 151-158 (2022)
Coronaviruses (CoVs) have the largest genome among RNA viruses and store large amounts of information without genome integration as they replicate in the cell cytoplasm. The replication of the virus is a continuous process, whereas the transcription
Externí odkaz:
https://doaj.org/article/e04daf16ecae41259caffc07dcb5dc21
Autor:
I. Gonzalez-Valdes, Alessia Ferrarini, Cristina Lorenzo, Christian E. Busse, Almudena R. Ramiro, Elena Bonzón-Kulichenko, Pilar Delgado, Sonia M. Mur, Jesús Vázquez, José Luis Martín-Ventura, Raquel Roldan-Montero, Hedda Wardemann, Alejandro Sanz-Bravo, Diego Martinez-Lopez, Inmaculada Martos-Folgado
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
Cardiovascular disease (CVD) is the leading cause of mortality in the world, with most CVD-related deaths resulting from myocardial infarction or stroke. The main underlying cause of thrombosis and cardiovascular events is atherosclerosis, an inflamm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6066811d5f459db77b13f657d725594
http://hdl.handle.net/10261/262573
http://hdl.handle.net/10261/262573
Autor:
Adrián Martin-Esteban, Alejandro Sanz-Bravo, Pablo Guasp, Jonas Kuiper, Marina Garcia-Peyro, Eilon Barnea, Arie Admon, Jose Antonio Lopez de Castro
Publikováno v:
Molecular Immunology. 150:20
Autor:
Jonas J.W. Kuiper, Eilon Barnea, Arie Admon, Marina García-Peydró, Adrian Martín-Esteban, Alejandro Sanz-Bravo, José A. López de Castro
Publikováno v:
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
Virtually all patients of the rare inflammatory eye disease birdshot chorioretinopathy (BSCR) carry the HLA-A*29:02 allele. BSCR is also associated with endoplasmic reticulum aminopeptidase 2 (ERAP2), an enzyme involved in processing HLA class I liga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12c2bcdd2ee4c27bd7ebb674c1a567cb
https://saludmadrid.ibai.com/handle/20.500.12530/36710
https://saludmadrid.ibai.com/handle/20.500.12530/36710
Autor:
Eilon Barnea, Alejandro Sanz-Bravo, Adrian Martín-Esteban, José A. López de Castro, Arie Admon, Carlos Alvarez-Navarro
Publikováno v:
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
The Endoplasmic reticulum aminopeptidase I (ERAP1) trims peptides to their optimal size for binding to Major Histocompatibility Complex class I proteins. The natural polymorphism of this enzyme is associated with ankylosing spondylitis (AS) in epista
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe8994f7cc8bf7cd13970c4473bd4605
https://saludmadrid.ibai.com/handle/20.500.12530/37142
https://saludmadrid.ibai.com/handle/20.500.12530/37142
Autor:
Marina S. Mazariegos, José A. López de Castro, Alejandro Sanz-Bravo, José Ribas Milanez de Campos
Publikováno v:
Arthritis & Rheumatology. 67:692-701
Objective To characterize the alterations, as well as their mechanisms, induced in the HLA–B27–bound peptidome expressed in live cells by the natural ERAP1 polymorphisms predisposing to ankylosing spondylitis (AS): R528K and N575D/Q725R. Methods
Autor:
Patricia Gómez-Molina, Alejandro Sanz-Bravo, Carlos Alvarez-Navarro, Eilon Barnea, Miguel Marcilla, José A. López de Castro, Arie Admon, Noel García-Medel
Publikováno v:
Molecular & Cellular Proteomics. 13:3367-3380
HLA-B27 is strongly associated with ankylosing spondylitis (AS). We analyzed the relationship between structure, peptide specificity, folding, and stability of the seven major HLA-B27 subtypes to determine the role of their constitutive peptidomes in
Autor:
José A. López de Castro, Pablo Guasp, Eilon Barnea, Arie Admon, Adrian Martín-Esteban, Alejandro Sanz-Bravo
Publikováno v:
Journal of autoimmunity. 79
Ankylosing spondylitis (AS) is an inflammatory disease strongly associated with the Major Histocompatibility Complex class I (MHC-I) allotype HLA-B*27. The endoplasmic reticulum aminopeptidases (ERAP)1 and 2, which trim peptides to their optimal leng
Autor:
José A. López de Castro, Ariadna Brito, Pablo Guasp, Alejandro Sanz-Bravo, Carlos Alvarez-Navarro, Adrian Martín-Esteban
Publikováno v:
Molecular immunology. 77
The inflammatory diseases that are most strongly associated with major histocompatibility Complex class I (MHC-I) alleles are also influenced by endoplasmic reticulum aminopeptidase (ERAP) 1 and/or 2, often in epistasis with the susceptibility MHC-I