Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Alejandro Salguero-Jiménez"'
Autor:
Alejandro Salguero-Jiménez, Joaquim Grego-Bessa, Gaetano D'Amato, Luis J Jiménez-Borreguero, José Luis de la Pompa
Publikováno v:
PLoS ONE, Vol 13, Iss 12, p e0203100 (2018)
During vertebrate cardiac development NOTCH signaling activity in the endocardium is essential for the crosstalk between endocardium and myocardium that initiates ventricular trabeculation and valve primordium formation. This crosstalk leads later to
Externí odkaz:
https://doaj.org/article/ec82dc3876b8451197920a6a45b2c0ed
Autor:
Marcos Siguero-Álvarez, Alejandro Salguero-Jiménez, Joaquim Grego-Bessa, Jorge de la Barrera, Donal MacGrogan, Belén Prados, Fernando Sánchez-Sáez, Rebeca Piñeiro-Sabarís, Natalia Felipe-Medina, Carlos Torroja, Manuel José Gómez, María Sabater-Molina, Rubén Escribá, Ivonne Richaud-Patin, Olalla Iglesias-García, Mauro Sbroggio, Sergio Callejas, Declan P. O’Regan, Kathryn A. McGurk, Ana Dopazo, Giovanna Giovinazzo, Borja Ibañez, Lorenzo Monserrat, José María Pérez-Pomares, Fátima Sánchez-Cabo, Alberto M. Pendas, Angel Raya, Juan R. Gimeno-Blanes, José Luis de la Pompa
The complex genetics underlying human cardiac disease is evidenced by its heterogenous manifestation, multigenic basis, and sporadic occurrence. These features have hampered disease modeling and mechanistic understanding. Here, we show that 2 structu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76c9d5c2f3da4e9446d77a979ec3f9f2
http://hdl.handle.net/2445/193600
http://hdl.handle.net/2445/193600
Autor:
Lorriane Eley, Ahlam MS Alqahtani, Donal MacGrogan, Rachel V Richardson, Lindsay Murphy, Alejandro Salguero-Jimenez, Marcos Sintes Rodriguez San Pedro, Shindi Tiurma, Lauren McCutcheon, Adam Gilmore, José Luis de La Pompa, Bill Chaudhry, Deborah J Henderson
Publikováno v:
eLife, Vol 7 (2018)
Abnormalities of the arterial valve leaflets, predominantly bicuspid aortic valve, are the commonest congenital malformations. Although many studies have investigated the development of the arterial valves, it has been assumed that, as with the atrio
Externí odkaz:
https://doaj.org/article/e17c18854ec64554b19872782cc6fda1