Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Alejandro Saettone"'
Publikováno v:
BMC Bioinformatics, Vol 20, Iss 1, Pp 1-17 (2019)
Abstract Background Chromatin immunoprecipitation coupled to next generation sequencing (ChIP-Seq) is a widely-used molecular method to investigate the function of chromatin-related proteins by identifying their associated DNA sequences on a genomic
Externí odkaz:
https://doaj.org/article/eceafd6ca4fc4ac191dac36ec20fd518
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
The eukaryotic histone acetylation cycle is composed of three classes of proteins, histone acetyltransferases (HATs) that add acetyl groups to lysine amino acids, bromodomain (BRD) containing proteins that are one of the most characterized of several
Externí odkaz:
https://doaj.org/article/167a81b6d5314c9685ecdeb61507b520
Autor:
Alejandro Saettone, Jyoti Garg, Jean-Philippe Lambert, Syed Nabeel-Shah, Marcelo Ponce, Alyson Burtch, Cristina Thuppu Mudalige, Anne-Claude Gingras, Ronald E. Pearlman, Jeffrey Fillingham
Publikováno v:
Epigenetics & Chromatin, Vol 11, Iss 1, Pp 1-20 (2018)
Abstract Background The chromatin remodelers of the SWI/SNF family are critical transcriptional regulators. Recognition of lysine acetylation through a bromodomain (BRD) component is key to SWI/SNF function; in most eukaryotes, this function is attri
Externí odkaz:
https://doaj.org/article/56375229106346adae0c58fc7d881d4c
Autor:
Syed Nabeel-Shah, Jack Greenblatt, Jean-Philippe Lambert, Suzanne Wahab, Zhaolei Zhang, Hyunmin Lee, Jacob Fine, Marcelo Ponce, Ronald E. Pearlman, Edyta Marcon, Jeffrey Fillingham, Nujhat Ahmed, Kanwal Ashraf, Alejandro Saettone, Joanna Derynck, Shuye Pu, Jyoti Garg
Publikováno v:
Nucleic Acids Research
Retinoblastoma-binding proteins 4 and 7 (RBBP4 and RBBP7) are two highly homologous human histone chaperones. They function in epigenetic regulation as subunits of multiple chromatin-related complexes and have been implicated in numerous cancers. Due
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdf95a56e759d3cfb7cf481761649053
http://europepmc.org/articles/PMC8216455
http://europepmc.org/articles/PMC8216455
Autor:
Jeffrey Fillingham, Jyoti Garg, Alejandro Saettone, Syed Nabeel-Shah, Kanwal Ashraf, Joanna Derynck, Anne-Claude Gingras, Jean-Philippe Lambert, Ronald E. Pearlman
Publikováno v:
Molecular Biology and Evolution
Epigenetic information, which can be passed on independently of the DNA sequence, is stored in part in the form of histone posttranslational modifications and specific histone variants. Although complexes necessary for deposition have been identified
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52a3282816b183f305d0577ae6c8eb29
https://doi.org/10.1093/molbev/msz039
https://doi.org/10.1093/molbev/msz039
Publikováno v:
Frontiers in Cell and Developmental Biology
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
The eukaryotic histone acetylation cycle is composed of three classes of proteins, histone acetyltransferases (HATs) that add acetyl groups to lysine amino acids, bromodomain (BRD) containing proteins that are one of the most characterized of several
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e970760652950d15dd4e33315935378b
http://europepmc.org/articles/PMC7339932
http://europepmc.org/articles/PMC7339932
Autor:
Joanna Derynck, Alejandro Saettone, Jean-Philippe Lambert, Jeffrey Fillingham, Ronald E. Pearlman, Jyoti Garg, Kanwal Ashraf, Syed Nabeel-Shah
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Chromatin organization influences most aspects of gene expression regulation. The linker histone H1, along with the core histones, is a key component of eukaryotic chromatin. Despite its critical roles in chromatin structure and function and gene reg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41325544d73adaff85dfad252aa215c8
https://doi.org/10.1038/s41598-019-56867-0
https://doi.org/10.1038/s41598-019-56867-0
Publikováno v:
eLS
Developmentally programmed DNA rearrangements are structural reorganizations of the genome that occur reproducibly during the development of a variety of organisms. In the majority of cases, programmed DNA rearrangements function to alter gene expres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a13ef4f052305f7811d265fc1675c0be
https://doi.org/10.1002/9780470015902.a0000595.pub3
https://doi.org/10.1002/9780470015902.a0000595.pub3
Publikováno v:
BMC Bioinformatics
BMC Bioinformatics, Vol 20, Iss 1, Pp 1-17 (2019)
BMC Bioinformatics, Vol 20, Iss 1, Pp 1-17 (2019)
Background: Chromatin immunoprecipitation coupled to next generation sequencing (ChIP-Seq) is a widely used technique to investigate the function of chromatin-related proteins in a genome-wide manner. ChIP-Seq generates large quantities of data which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d36ee6d0b8eeaf880419c1b4b1f0cde0
http://europepmc.org/articles/PMC6819487
http://europepmc.org/articles/PMC6819487
Autor:
Alejandro, Saettone, Syed, Nabeel-Shah, Jyoti, Garg, Jean-Philippe, Lambert, Ronald E, Pearlman, Jeffrey, Fillingham
Publikováno v:
Genes
Identification and characterization of protein complexes and interactomes has been essential to the understanding of fundamental nuclear processes including transcription, replication, recombination, and maintenance of genome stability. Despite signi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1b34eed80b994d8605c7529228582f02
https://pubmed.ncbi.nlm.nih.gov/31052454
https://pubmed.ncbi.nlm.nih.gov/31052454