Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Alejandro Sánchez Melgar"'
Autor:
Alejandro Sánchez Melgar, Valentina Vultaggio-Poma, José Luis Albasanz, Francesco Di Virgilio, Mairena Martín
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp S256- (2023)
Externí odkaz:
https://doaj.org/article/c0736958b65f47e2ae927adb89c4e4a3
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Despite great efforts, effective treatment against cancer has not yet been found. However, natural compounds such as the polyphenol resveratrol have emerged as promising preventive agent in cancer therapy. The mode of action of resveratrol is still p
Externí odkaz:
https://doaj.org/article/61bdf7f71d1343b3b72d107d55b4f462
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
Gliomas are the most common and aggressive primary tumors in the central nervous system. The nucleoside adenosine is considered to be one major constituent within the tumor microenvironment. The adenosine level mainly depends on two enzymatic activit
Externí odkaz:
https://doaj.org/article/36daa0fa6c5f4def8c85d9280757c432
Autor:
Alejandro Sánchez-Melgar, José Luis Albasanz, Christian Griñán-Ferré, Mercè Pallàs, Mairena Martín
Publikováno v:
Cells, Vol 9, Iss 7, p 1628 (2020)
Adenosine (ARs) and metabotropic glutamate receptors (mGluRs) are G-protein coupled receptors (GPCRs) that are modulated in the brain of SAMP8 mice, an animal model of Alzheimer’s disease (AD). In the present work, it is shown the presence of ARs a
Externí odkaz:
https://doaj.org/article/aab331f4f15149b5a8c268905c76ef93
Autor:
Gemma Navarro, Eva Martínez-Pinilla, Alejandro Sánchez-Melgar, Raquel Ortiz, Véronique Noé, Mairena Martín, Carlos Ciudad, Rafael Franco
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0176067 (2017)
The mode of action of trans-resveratrol, a promising lead compound for the development of neuroprotective drugs, is unknown. Data from a functional genomics study were retrieved with the aim to find differentially expressed genes that may be involved
Externí odkaz:
https://doaj.org/article/b4c914dadac94a3aa87a81469218f615
Publikováno v:
Frontiers in endocrinology. 13
Despite great efforts, effective treatment against cancer has not yet been found. However, natural compounds such as the polyphenol resveratrol have emerged as promising preventive agent in cancer therapy. The mode of action of resveratrol is still p
Autor:
Alejandro Sánchez-Melgar, Pedro J. Izquierdo-Ramírez, Christian Griñán-Ferré, Mercè Pallàs, Mairena Martín, José Luis Albasanz
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 14; Pages: 7580
Cholesterol metabolism seems dysregulated and linked to amyloid-β (Aβ) formation in neurodegeneration, but the underlying mechanisms are poorly known. Resveratrol (RSV) is a polyphenol with antioxidant activity and neuroprotective properties. Here,
Autor:
Valentina Vultaggio-Poma, Simonetta Falzoni, Paola Chiozzi, Alba Clara Sarti, Elena Adinolfi, Anna Lisa Giuliani, Alejandro Sánchez-Melgar, Paola Boldrini, Michele Zanoni, Anna Tesei, Paolo Pinton, Francesco Di Virgilio
Publikováno v:
RUIdeRA. Repositorio Institucional de la UCLM
instname
Theranostics
instname
Theranostics
Rationale: Caloric restriction improves the efficacy of anti-cancer therapy. This effect is largely dependent on the increase of the extracellular ATP concentration in the tumor microenvironment (TME). Pathways for ATP release triggered by nutrient d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::973a5c8587677662ce1c305d3d9ce75a
http://hdl.handle.net/10578/30129
http://hdl.handle.net/10578/30129
Publikováno v:
Journal of Caffeine and Adenosine Research. 9:167-179
The increase of neurodegenerative disease incidence with aging and the lack of effectiveness in present treatments lead to the exploration of new potential neuroprotective agents found in food. Man...
Autor:
Jana Selent, Mairena Martín, Ramon Guixà-González, José Luis Albasanz, Alejandro Sánchez-Melgar, Noureldin Saleh
Publikováno v:
RUIdeRA. Repositorio Institucional de la UCLM
instname
instname
Resveratrol (RSV) is a natural polyphenolic antioxidant with a proven protective role in several human diseases involving oxidative stress, although the molecular mechanism underlying this effect remains unclear. The present work tried to elucidate t