Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Alejandro Sánchez Melgar"'
Autor:
Alejandro Sánchez Melgar, Valentina Vultaggio-Poma, José Luis Albasanz, Francesco Di Virgilio, Mairena Martín
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp S256- (2023)
Externí odkaz:
https://doaj.org/article/c0736958b65f47e2ae927adb89c4e4a3
Autor:
Carmen Dimas-Benedicto, José Luis Albasanz, Laura M. Bermejo, Lucía Castro-Vázquez, Alejandro Sánchez-Melgar, Mairena Martín, Rosa M. Martínez-García
Publikováno v:
Nutrients, Vol 16, Iss 16, p 2808 (2024)
Iron is a key nutrient for cognitive function. During periods of high academic demand, brain and cognitive activity increase, potentially affecting iron intake and reserves. The present study aimed to investigate the impact of iron levels on cognitiv
Externí odkaz:
https://doaj.org/article/022dfeeaf8874f08a4b9ddeb8e8f4468
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Despite great efforts, effective treatment against cancer has not yet been found. However, natural compounds such as the polyphenol resveratrol have emerged as promising preventive agent in cancer therapy. The mode of action of resveratrol is still p
Externí odkaz:
https://doaj.org/article/61bdf7f71d1343b3b72d107d55b4f462
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
Gliomas are the most common and aggressive primary tumors in the central nervous system. The nucleoside adenosine is considered to be one major constituent within the tumor microenvironment. The adenosine level mainly depends on two enzymatic activit
Externí odkaz:
https://doaj.org/article/36daa0fa6c5f4def8c85d9280757c432
Autor:
Alejandro Sánchez-Melgar, Pedro José Izquierdo-Ramírez, Verónica Palomera-Ávalos, Mercè Pallàs, José Luis Albasanz, Mairena Martín
Publikováno v:
Nutrients, Vol 13, Iss 9, p 3040 (2021)
Neurodegenerative disorders are devastating diseases in which aging is a major risk factor. High-fat diet (HFD) seems to contribute to cognition deterioration, but the underlying mechanisms are poorly understood. Moreover, resveratrol (RSV) has been
Externí odkaz:
https://doaj.org/article/13a86de1709741db8f0076f7087b48b1
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 19, p 7300 (2020)
Adenosine is a neuromodulator that has been involved in aging and neurodegenerative diseases as Alzheimer’s disease (AD). In the present work, we analyzed the possible modulation of purine metabolites, 5’nucleotidase (5′NT) and adenosine deamin
Externí odkaz:
https://doaj.org/article/2b78612b536342559649b51a974c3bee
Autor:
Alejandro Sánchez-Melgar, José Luis Albasanz, Christian Griñán-Ferré, Mercè Pallàs, Mairena Martín
Publikováno v:
Cells, Vol 9, Iss 7, p 1628 (2020)
Adenosine (ARs) and metabotropic glutamate receptors (mGluRs) are G-protein coupled receptors (GPCRs) that are modulated in the brain of SAMP8 mice, an animal model of Alzheimer’s disease (AD). In the present work, it is shown the presence of ARs a
Externí odkaz:
https://doaj.org/article/aab331f4f15149b5a8c268905c76ef93
Publikováno v:
Frontiers in endocrinology. 13
Despite great efforts, effective treatment against cancer has not yet been found. However, natural compounds such as the polyphenol resveratrol have emerged as promising preventive agent in cancer therapy. The mode of action of resveratrol is still p
Autor:
Alejandro Sánchez-Melgar, Pedro J. Izquierdo-Ramírez, Christian Griñán-Ferré, Mercè Pallàs, Mairena Martín, José Luis Albasanz
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 14; Pages: 7580
Cholesterol metabolism seems dysregulated and linked to amyloid-β (Aβ) formation in neurodegeneration, but the underlying mechanisms are poorly known. Resveratrol (RSV) is a polyphenol with antioxidant activity and neuroprotective properties. Here,
Autor:
Gemma Navarro, Eva Martínez-Pinilla, Alejandro Sánchez-Melgar, Raquel Ortiz, Véronique Noé, Mairena Martín, Carlos Ciudad, Rafael Franco
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0176067 (2017)
The mode of action of trans-resveratrol, a promising lead compound for the development of neuroprotective drugs, is unknown. Data from a functional genomics study were retrieved with the aim to find differentially expressed genes that may be involved
Externí odkaz:
https://doaj.org/article/b4c914dadac94a3aa87a81469218f615